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Treatment and Clinical Management of Necrotizing Pancreatitis

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 20 September 2026

Special Issue Editor


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Guest Editor
Department of Surgery, Eastern Virginia Medical School, Norfolk, VA 23507, USA
Interests: necrotizing pancreatitis; infected necrosis; step-up approach; necrosectomy; minimally invasive surgery; artificial intelligence; lumen-apposing metal stent; pancreatic necrosis

Special Issue Information

Dear Colleagues,

Necrotizing pancreatitis remains one of the most complex and lethal entities of intra-abdominal disease, with major gaps in evidence and wide variability in global practice. It has evolved from a condition managed primarily with early open surgery to one treated with delayed, minimally invasive, multidisciplinary strategies. Despite these advances, it remains associated with high morbidity, prolonged hospitalizations, significant mortality, and persistent gaps in standardized care. This Special Issue aims to synthesize current knowledge, identify unresolved challenges, and promote innovations that improve outcomes in necrotizing pancreatitis. Scope includes diagnostics, intervention timing, minimally invasive techniques, management of complications, ICU management, and long-term sequelae. Emerging areas include optimized endoscopic step-up algorithms, refinement of lumen-apposing metal stent protocols, advanced techniques for management of bleeding complications, and targeted therapies for inflammatory modulation. We welcome original research and review articles addressing key areas of interest in necrotizing pancreatitis.

Dr. Apostolos Gaitanidis
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • necrotizing pancreatitis
  • infected necrosis
  • step-up approach
  • necrosectomy
  • minimally invasive surgery
  • artificial intelligence
  • lumen-apposing metal stent
  • pancreatic necrosis

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Published Papers

This special issue is now open for submission.
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