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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Breakthroughs in Spine Biomechanics: Diagnostics and Treatment Approaches for Body Posture, Scoliosis and Chronic Back Pain

edited by

Maciej Rachwał

and

Joanna Baran

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1382 | Submission Open

Keywords: spinal biomechanics; spinal pathologies; idiopathic scoliosis; postural abnormalities; spinal pain syndromes; spinal deformities; chronic spinal pain

(This special issue belongs to the Section Orthopedics)

Deep Vein Thrombosis and Pulmonary Embolism: Clinical Treatment and Management—Second Edition

edited by

Pablo Demelo-Rodríguez

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1178 | Submission Open

Keywords: pulmonary embolism; thrombophilia; deep vein thrombosis; venous thromboembolism; anticoagulation therapy; thrombectomy; bleeding; cancer-associated thrombosis

(This special issue belongs to the Section Hematology)

Orthopedic Trauma: Diagnosis, Treatment and Rehabilitation

edited by

Emmanouil Liodakis

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1129 | Submission Open

Keywords: orthopedic trauma; fragility fractures; biomechanics; bone defect; pelvic ring; acetabular fractures; amputation; re-habilitation

(This special issue belongs to the Section Orthopedics)

Current Opinion of Reconstructive and Aesthetic Breast Surgery

edited by

Lukas Prantl

, Konstantin Frank and Vanessa Brébant

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1126 | Submission Open

Keywords: reconstructive breast surgery; lipofilling; microsurgery; aesthetic breast surgery; PROM; digital anthropometry; autologous fat transfer; ADM; synthetic mesh; BIA-ALCL; BII

(This special issue belongs to the Section General Surgery)

Clinical Translation of Technological Innovations in Diabetes Therapeutics

edited by

Nowreen Haq

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1120 | Submission Open

Keywords: diabetes management; remote patient monitoring (RPM); artificial intelligence (AI); machine learning (ML); wearable sensors; point-of-care diagnostics; centrifugal microfluidics; glucose monitoring

(This special issue belongs to the Section Endocrinology & Metabolism)

New Insights in Cognitive Aging and Mild Cognitive Impairment

edited by

Irene Fernández

and

Laura Galiana

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1095 | Submission Open

Keywords: cognitive aging; mild cognitive impairment; normative aging; neuropsychological assessment; diagnosis; gerontology; prevention; intervention; multidisciplinary approach; measurement

(This special issue belongs to the Section Geriatric Medicine)

Rising Star: Advanced Physical Therapy and Expansion

edited by

Hyolyun Roh

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1085 | Submission Open

Keywords: physical therapy; digital therapeutic technology; geriatric diseases; pediatric; psychology of physical therapies; clinical approach

(This special issue belongs to the Section Clinical Rehabilitation)

Cancer Immunotherapy: Recent Advances and Clinical Challenges

edited by

Antonello Veccia

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1065 | Submission Open

Keywords: immune checkpoint inhibitors; solid tumors; early-stage disease; metastatic disease; prognostic factors; biomarkers; resistance mechanisms

(This special issue belongs to the Section Oncology)

Updates on Neurosurgical Techniques, Management, and Outcomes for Intracranial Hemorrhages

edited by Bruno Splavski

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1059 | Submission Open

Keywords: minimally invasive neurosurgery; neuro-intervention endovascular techniques; intracranial hemorrhage; stroke; hemorrhagic; ischemic; neurosurgical decision-making; long-term outcomes in neurosurgery

(This special issue belongs to the Section Clinical Neurology)

Advances in the Field of Cutaneous Malignancies: Background and Clinical Management

edited by

and

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1048 | Submission Open

Keywords: dermatology; skin cancer; diagnosis; melanoma; basal cell carcinoma; squamous cell carcinoma; imaging; artificial intelligence; dermoscopy; treatment

(This special issue belongs to the Section Dermatology)

Novel Developments in Digestive Endoscopy

edited by

Arnaldo Amato

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1042 | Submission Open

Keywords: endoscopy for IBD; AI in endoscopy; therapeutic endoscopy; EUS; interventional EUS; AI in digestive endoscopy; quality in endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Applications of Cardiac Imaging: 2nd Edition

edited by Maria Concetta Pastore

submission deadline 20 Feb 2026 | 2 articles | Viewed by 1033 | Submission Open

Keywords: cardiac imaging; echocardiography; magnetic resonance imaging; computed tomography; nuclear imaging; heart failure; valvular heart disease; congenital heart disease

(This special issue belongs to the Section Cardiology)

Hepatobiliary Surgery: State of the Art and Future Perspectives

edited by

Teresa Perra

and

Alberto Porcu

submission deadline 20 Feb 2026 | 1 articles | Viewed by 1013 | Submission Open

Keywords: hepatobiliary surgery; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; benign liver lesions

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Opinion in Dental Implant Surgery and Peri-Implant Disease

edited by

Giorgio Lombardo

and Giovanni Corrocher

submission deadline 20 Feb 2026 | 1 articles | Viewed by 967 | Submission Open

Keywords: dental implant surgery; dental implantology; peri-implant disease; oral surgery; dental implantology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances and Updates in Migraine

edited by

Hartmut Göbel

and Carl H. Göbel

submission deadline 20 Feb 2026 | 2 articles | Viewed by 942 | Submission Open

Keywords: migraine; chronic migraine; headache disorders; CGRP antibodies; gepants; ditans; triptans; precision medicine; neuromodulation; comorbidities; disability burden; pediatric migraine; ICHD-3 classification; neurotransmitters; preventive therapy; translational headache research

(This special issue belongs to the Section Clinical Neurology)

Advances in Maternal–Fetal Medicine

edited by

C. Andrew Combs

submission deadline 20 Feb 2026 | 1 articles | Viewed by 898 | Submission Open

Keywords: maternal– fetal medicine; obstetric ultrasound; preterm birth; preeclampsia; pregnancy complications; artificial intelligence

(This special issue belongs to the Section Obstetrics & Gynecology)

Treatment and Long-Term Outcome of Fracture

edited by

Corrado Ciatti

Edoardo Bori

and Fabrizio Quattrini

submission deadline 20 Feb 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: traumatology; osteosynthesis; plating; nailing; osteosynthesis devices; surgical technique; approach

(This special issue belongs to the Section Orthopedics)

Age-Related Macular Degeneration: Challenges and Opportunities

edited by Deepayan Kar

submission deadline 20 Feb 2026 | 1 articles | Viewed by 872 | Submission Open

Keywords: age-related macular degeneration; imaging biomarkers; visual function testing; optical coherence tomography; anti-VEGF; complement; artificial intelligence

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Treatment of Gastrointestinal Malignancies

edited by

Carmelo Laface

and Gianmauro Numico

submission deadline 20 Feb 2026 | 1 articles | Viewed by 811 | Submission Open

Keywords: gastrointestinal cancers; immunotherapy; targeted therapy; chemotherapy; microsatellite instability; driver mutations

(This special issue belongs to the Section Oncology)

New Insights into Orthodontic Treatment

edited by Federico Brugnami and Simonetta Meuli

submission deadline 20 Feb 2026 | 1 articles | Viewed by 771 | Submission Open

Keywords: digital orthodontics; clear aligners; artificial intelligence; digital superimpositions; cone beam computed tomography; growing patients; periodontal patients; maxillofacial surgery; long-term stability; prediction of orthodontic movements

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Challenges and Innovations in Emergency Medicine: From Prehospital Care to Critical Decision-Making in the Emergency Department

edited by

Efstratios Karagiannidis

, Barbara P. Fyntanidou and

Aikaterini Apostolopoulou

submission deadline 20 Feb 2026 | 1 articles | Viewed by 706 | Submission Open

Keywords: emergency medicine; prehospital care; triage strategies; acute care; point-of-care diagnostics; artificial intelligence; telemedicine; emergency department; patient flow; healthcare systems; burnout in emergency care

(This special issue belongs to the Section Emergency Medicine)

Minimally Invasive Surgery for Gastrointestinal Disorder

edited by

Amosy Ephreim M'Koma

submission deadline 20 Feb 2026 | 1 articles | Viewed by 646 | Submission Open

Keywords: minimally invasive surgery; gastrointestinal disorder; laparoscopy; robotic surgery; colorectal surgery; gastric surgery; endoscopic technique; oncological outcomes; surgical innovation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Update on Cardiac Rehabilitation

edited by

Bruno Bordoni

submission deadline 20 Feb 2026 | Viewed by 635 | Submission Open

Keywords: cardiac rehabilitation; cardiovascular disease; physiotherapy; interprofessional intervention; exercise training; nutritional counseling; psychosocial support; secondary prevention; rehabilitation modalities; rehabilitation tools

(This special issue belongs to the Section Clinical Rehabilitation)

Diagnosis and Treatment of Cardiovascular Diseases in the Elderly

edited by

Carmelo Massimiliano Rao

submission deadline 20 Feb 2026 | 1 articles | Viewed by 596 | Submission Open

Keywords: cardiovascular diseases; elderly population; diagnosis and management; age-related pathophysiology; frailty and cognitive impairment

(This special issue belongs to the Section Geriatric Medicine)

Novel Research in Pediatric Dentistry: 2nd Edition

edited by Christian Hirsch and

Katrin Bekes

submission deadline 20 Feb 2026 | 1 articles | Viewed by 504 | Submission Open

Keywords: early childhood caries; primary teeth; caries prevention; caries treatment; behavioral management; molar incisor hypomineralization; dental trauma; sedation; oral health-related quality of life

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

State of the Art in Interventional Cardiology

edited by Antonios Karanasos

submission deadline 20 Feb 2026 | Viewed by 470 | Submission Open

Keywords: interventional cardiology; intravascular imaging; structural interventions; TAVI; vascular access; percutaneous coronary intervention; coronary stenting; cardiovascular diseases

(This special issue belongs to the Section Cardiology)

Cardiac Anesthesia: Current Research and Future Prospects

edited by

Fabio Sangalli

and Lorenzo Stephan Cesare Grazioli

submission deadline 20 Feb 2026 | Viewed by 406 | Submission Open

Keywords: cardiac anesthesia; cardiac surgery; echocardiography; interventional cardiology; anesthesia; cardiology

(This special issue belongs to the Section Anesthesiology)

Advances in the Personalized Management of Chronic Obstructive Pulmonary Disease (COPD)

edited by

Athena Gogali

and Georgios Hillas

submission deadline 20 Feb 2026 | 1 articles | Viewed by 355 | Submission Open

Keywords: artificial intelligence; biologics; biomarkers; diagnostics; oscillometry; COPD pharmacotherapy; imaging

(This special issue belongs to the Section Respiratory Medicine)

Current and Emerging Treatment Options in Atrial Fibrillation: 2nd Edition

edited by

Marco Valerio Mariani

submission deadline 20 Feb 2026 | Viewed by 345 | Submission Open

Keywords: atrial fibrillation; left atrial appendage closure; ablation techniques; personalized medicine in AF treatment; cardioversion methods

(This special issue belongs to the Section Cardiology)

Disease Modifying Activity in Psoriasis and Atopic Dermatitis

edited by

Elena Pezzolo

and

Paolo Gisondi

submission deadline 20 Feb 2026 | Viewed by 310 | Submission Open

Keywords: atopic dermatitis; biologics; psoriasis; disease-modifying treatment; small molecules; type 2 inflammation

(This special issue belongs to the Section Dermatology)

Novel Insights for Imaging and Therapy in Maternal and Fetal Medicine

edited by Xin Kang

submission deadline 20 Feb 2026 | Viewed by 269 | Submission Open

Keywords: prenatal imaging; prenatal diagnosis; fetal virtual autopsy; preeclampsia; macrosomia; preterm birth; pelvic floor

(This special issue belongs to the Section Obstetrics & Gynecology)

Endocrine Disorders in Children: 2nd Edition

edited by

Juan Pedro López-Siguero

submission deadline 20 Feb 2026 | Viewed by 194 | Submission Open

Keywords: endocrinology; pediatrics; hormones; genetics; growth; nutrition; development ; adolescence ; prevention

(This special issue belongs to the Section Clinical Pediatrics)

Recent Advances and Future Perspectives on Spinal Surgeries

edited by

Sung-kyu Kim

submission deadline 20 Feb 2026 | Viewed by 179 | Submission Open

Keywords: minimally invasive spine procedures; robotic-assisted spine surgery; image-guided navigation; spinal implants and biomaterials; artificial intelligence in spinal care; regenerative spine therapies; clinical outcomes in spine surgery; future trends in spinal interventions

(This special issue belongs to the Section Orthopedics)

Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation

edited by

Jeremie Oliver Piña

submission deadline 20 Feb 2026 | Viewed by 174 | Submission Open

Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Hypercholesterolemia: Update on Treatment Approaches and Outcomes

edited by

Massimiliano Ruscica

and Lucia Barbieri

submission deadline 20 Feb 2026 | Viewed by 173 | Submission Open

Keywords: hypercholesterolemia; dyslipidemia; atherosclerosis; cardiovascular risk; LDL; HDL; lipoprotein(a)

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in the Diagnosis and Management of Atherosclerosis

edited by

Adrian Covic

and

Cristian Stătescu

submission deadline 20 Feb 2026 | Viewed by 171 | Submission Open

Keywords: atherosclerosis; cardiovascular disease; coronary artery disease; endothelial function; acute coronary syndromes

(This special issue belongs to the Section Cardiology)

Progress and Innovation in the Clinical Management of Psychosis

edited by

Valerio Ricci

submission deadline 20 Feb 2026 | Viewed by 170 | Submission Open

Keywords: psychosis; schizophrenia; clinical interventions; neurobiological mechanisms; early intervention

(This special issue belongs to the Section Mental Health)

Innovations and Challenges in the Burden and Rehabilitation of Musculoskeletal Disorders

edited by

Carla Sílvia Fernandes

and

Marta Campos Ferreira

submission deadline 20 Feb 2026 | Viewed by 162 | Submission Open

Keywords: musculoskeletal diseases; rehabilitation; physical therapy modalities; telemedicine; mobile applications; health information technology; patient-centered care; quality of life; health care innovation

(This special issue belongs to the Section Clinical Rehabilitation)

Advances and Innovations in Radiology: From Contrast-Enhanced Mammography to Artificial Intelligence and Beyond

edited by

Luca Nicosia

submission deadline 20 Feb 2026 | Viewed by 157 | Submission Open

Keywords: contrast-enhanced mammography (CEM); artificial intelligence; radiomics; diagnostic imaging innovations; inter-ventional radiology

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Myocarditis and Pericarditis: Clinical Advances and Current Challenges

edited by

Ankit Agrawal

and

Tom Kai Ming Wang

submission deadline 20 Feb 2026 | Viewed by 150 | Submission Open

Keywords: pericarditis; myocarditis; pericardial effusion; cardiac tamponade; interleukin-1 inhibitors; pericardium

(This special issue belongs to the Section Cardiovascular Medicine)

Rheumatoid Arthritis: Insights into Appropriate Diagnosis, Treatment and Management

edited by

Satoshi Takanashi

submission deadline 20 Feb 2026 | Viewed by 141 | Submission Open

Keywords: rheumatoid arthritis; precision medicine; difficult-to-treat rheumatoid arthritis; late-onset rheumatoid arthritis; ageing society; comorbidities

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Updates on Acromegaly

edited by

Marek Bolanowski

, Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek

submission deadline 20 Feb 2026 | Viewed by 138 | Submission Open

Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma

(This special issue belongs to the Section Endocrinology & Metabolism)

Metastatic Colorectal Cancer Beyond Second-Line Treatment

edited by Jacopo Giuliani

submission deadline 20 Feb 2026 | Viewed by 131 | Submission Open

Keywords: metastatic colorectal cancer; subsequent lines; chemotherapy; targeted agents; radiotherapy; local therapy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Advances in Posttraumatic Stress Disorder (PTSD): Clinical Update

edited by An-Fu Hsiao and

Michael Hollifield

submission deadline 20 Feb 2026 | Viewed by 129 | Submission Open

Keywords: PTSD; stellate ganglion block; transcranial magnetic stimulations; neurobiology; trauma disorders; mind– body medicine; psychophysiology

(This special issue belongs to the Section Mental Health)

Clinical Advances in Meningioma Surgery

edited by

Makoto Nakamura

submission deadline 20 Feb 2026 | Viewed by 126 | Submission Open

Keywords: meningioma; cranial neurosurgery; brain tumors; skull base surgery; endoscopic neurosurgery; intraoperative techniques; surgical outcomes; minimally invasive neurosurgery; perioperative management; clinical meningioma research

(This special issue belongs to the Section Clinical Neurology)

Bleeding and Thrombotic Complications in Patients with Premalignant Hematologic Conditions: Diagnostic and Therapeutic Challenges

edited by Vasiliki Gkalea and Despina Fotiou

submission deadline 20 Feb 2026 | Viewed by 119 | Submission Open

Keywords: bleeding; thrombosis; hematologic malignancies; premalignant hematologic conditions; clonal hematopoiesis of indeterminate potential (CHIP); clonal cytopenias of undetermined significance (CCUS); monoclonal gammopathy of undetermined significance (MGUS); monoclonal B-cell lymphocytosis (MBL); monoclonal gammopathy of thrombotic significance (MGTS); VITT-like MGTS

(This special issue belongs to the Section Hematology)

Optimizing Rehabilitation in Kidney Disease

edited by Henry H. L. Wu and Rajkumar Chinnadurai

submission deadline 20 Feb 2026 | Viewed by 113 | Submission Open

Keywords: chronic kidney disease; renal rehabilitation; exercise intervention; nutrition; multidisciplinary; frailty; physical conditioning

(This special issue belongs to the Section Clinical Rehabilitation)

Endoscopic Imaging for the Diagnosis and Treatment of Gastrointestinal Diseases

edited by Mariana Jinga and

Daniel Vasile Balaban

submission deadline 20 Feb 2026 | Viewed by 109 | Submission Open

Keywords: endoscopy; endoscopic ultrasound; endoscopic retrograde cholangiopancreatography; artificial intelligence; diagnosis; therapy; decision making; endobiopsy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Advances in Sepsis and Septic Shock

edited by

Lucia Filippi

and Lorenzo Ghiadoni

submission deadline 20 Feb 2026 | Viewed by 105 | Submission Open

Keywords: sepsis-induced coagulopathy; endothelial dysfunction in sepsis; fluid balance in sepsis

(This special issue belongs to the Section Emergency Medicine)

New Insights into Management of Chronic Rhinosinusitis

edited by

Giandomenico Maggiore

submission deadline 20 Feb 2026 | Viewed by 91 | Submission Open

Keywords: chronic rhinosinusitis; management; surgery; minimally invasive surgery; surgical oncology; cancer surgery; skull base surgery; hoarseness; laryngeal neoplasms; laryngoscopy; general surgery; X-ray computed tomography

(This special issue belongs to the Section Otolaryngology)

Displaying special issue 501-550 on page 11 of 32.

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