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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Integrated Assessment and Management of Heart Failure Syndromes
edited by Damiano Magrì and Emiliano Fiori
submission deadline 25 Mar 2027 | Viewed by 351 | Submission Open
Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies
(This special issue belongs to the Section Cardiology)
Advances in Cardiac Electrophysiology: Mechanisms of Arrhythmias and Ablation Technologies
edited by , Valeria Rella and Emanuele Curti
submission deadline 25 Mar 2027 | Viewed by 253 | Submission Open
Keywords: cardiac arrhythmias; cardiac electrophysiology; arrhythmias pathophysiology; arrhythmia mechanisms; catheter ablation; electro-anatomical mapping; mapping techniques; pacing maneuvers; pulsed field ablation; radiofrequency; autonomic modulation; cardioneuroablation; imaging; hybrid ablation; clinical outcomes
(This special issue belongs to the Section Cardiology)
Advanced and Personalized Drug Delivery Systems: From Formulation Science to Clinical Application
edited by
submission deadline 25 Mar 2027 | Viewed by 180 | Submission Open
Keywords: drug delivery systems; nanoparticles; lipid-based carriers; transdermal delivery; controlled release; bioavailability; pharmaceutical nanotechnology; personalized medicine; polymeric carriers; targeted therapy; in vitro–in vivo cor-relation; pharmaceutical compounding; stimuli-responsive drug delivery; clinical pharmacokinetics; innovative dosage forms
(This special issue belongs to the Section Pharmacology)
Insights into Infectious Disease Epidemiology, Management and Impact on Public Health
edited by Krystyna Dobrowolska, and
submission deadline 25 Mar 2027 | Viewed by 178 | Submission Open
Keywords: infectious disease; viral infections; bacterial infections; epidemiology; public health
(This special issue belongs to the Section Epidemiology & Public Health)
Current Updates and Advances in Hemodialysis—2nd Edition
edited by Edita Žiginskienė
submission deadline 25 Mar 2027 | Viewed by 144 | Submission Open
Keywords: kidney replacement therapy; hemodialysis; hemodiafiltration; vascular access; dialysis membranes; dialysis complications; dialysis adequacy; outcomes
(This special issue belongs to the Section Nephrology & Urology)
Robotic Pancreatic Surgery: Innovation, Outcomes, and Future Directions
edited by , Dimitrios Dimitroulis and
submission deadline 25 Mar 2027 | Viewed by 132 | Submission Open
Keywords: robotic surgery; pancreatic surgery; Whipple; distal pancreatectomy; spleen preserving; pylorus preserving; pan-creaticoduodenectomy; enucleation; POPF; delayed gastric emptying
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Hypertrophic Cardiomyopathy: Diagnosis and Management
edited by Muhammad Fuad Jan and Abdul Jamil Tajik
submission deadline 25 Mar 2027 | Viewed by 63 | Submission Open
Keywords: hypertrophic cardiomyopathy; genetics; heart failure; sudden death; echocardiography
(This special issue belongs to the Section Cardiology)
Retinal Diseases: Innovations in Diagnosis, Imaging, and Treatment
edited by and Hakan Kaymak
submission deadline 25 Mar 2027 | Viewed by 54 | Submission Open
Keywords: retinal diseases; biomarkers; spectral-domain optical coherence tomography; vitreoretinal surgery; retinal laser therapy
(This special issue belongs to the Section Ophthalmology)
The Future Direction of Medical Imaging in Hepato-Bilio-Pancreatic Oncology: Challenges and Opportunities
edited by
submission deadline 26 Mar 2027 | 2 articles | Viewed by 2701 | Submission Open
Keywords: MRI; CT; molecular imaging; radiomics; imaging; radiogenomics; precision medicine; outcome prediction; cholangiocarcinoma; pancreatic cancer; imaging biomarkers; treatment response
(This special issue belongs to the Section Nuclear Medicine & Radiology)
Pulmonary Hypertension: Clinical Perspectives
edited by and Maria Wieteska-Miłek
submission deadline 27 Mar 2027 | 1 articles | Viewed by 365 | Submission Open
Keywords: pulmonary hypertension (PH); pulmonary arterial hypertension (PAH); chronic thromboembolic pulmonary hypertension (CTEPH); chronic thromboembolic pulmonary disease; pulmonary embolism; diagnosis; treatment; quality of life; physical activity; prognostic factors; nonpharmacological treatment
(This special issue belongs to the Section Respiratory Medicine)
Neuromuscular Diseases and Musculoskeletal Disorders
edited by
submission deadline 28 Mar 2027 | 5 articles | Viewed by 8898 | Submission Open
Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation
(This special issue belongs to the Section Clinical Neurology)
Mitral Valve Stenosis or Aortic Valve Stenosis: Progress from Diagnosis to Treatment
edited by Francesco Melillo
submission deadline 28 Mar 2027 | 3 articles | Viewed by 8253 | Submission Open
Keywords: aortic stenosis; mitral stenosis; TAVI
(This special issue belongs to the Section Cardiology)
Management of Female Pelvic Floor Disorders and Incontinence
edited by Luis López Fando
submission deadline 28 Mar 2027 | 4 articles | Viewed by 2985 | Submission Open
Keywords: pelvic floor disorders; urinary incontinence; pelvic organ prolapse; reconstructive urology; voiding dysfunction; multidisciplinary care; surgical techniques; urodynamics; patient-centered outcomes; digital learning in urology
(This special issue belongs to the Section Nephrology & Urology)
Current Challenges in Oral Surgery and Pathology
edited by
submission deadline 28 Mar 2027 | 2 articles | Viewed by 2311 | Submission Open
Keywords: oral medicine; oral pathology; oral surgery; ONJ; MRONJ; BRONJ; laser
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Cardiovascular Risk in COVID-19 Survivors: From Emergency Department Management to Cardiovascular Rehabilitation
edited by and Stela Iurciuc
submission deadline 28 Mar 2027 | 1 articles | Viewed by 536 | Submission Open
Keywords: cardiovascular risk management; COVID-19 survivors; long COVID syndrome; post-acute sequelae of SARS-CoV-2 infection (PASC); emergency department; cardiovascular rehabilitation; risk stratification; integrated care
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)
edited by , and Nancy McNamara
submission deadline 29 Mar 2027 | Viewed by 574 | Submission Open
Keywords: Sjogren; Sjogren’s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)
(This special issue belongs to the Section Immunology & Rheumatology)
Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection
edited by and Phoebus Madianos
submission deadline 30 Mar 2027 | 3 articles | Viewed by 5752 | Submission Open
Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Approaches to Prevention and Management of Postoperative Complications in Minimally Invasive Surgery
edited by Shingo Tsujinaka
submission deadline 30 Mar 2027 | 4 articles | Viewed by 3513 | Submission Open
Keywords: minimally invasive surgery; postoperative complications; preventive measures; risk assessment; surgical techniques; patient optimization; complication management; surgical outcomes; patient satisfaction; patient-reported outcomes
(This special issue belongs to the Section General Surgery)
Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life
edited by and Shaye Kivity
submission deadline 30 Mar 2027 | 2 articles | Viewed by 2135 | Submission Open
Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical and Laboratory Applications of Artificial Intelligence in Haematology
edited by and Bingwen Eugene Fan
submission deadline 30 Mar 2027 | 1 articles | Viewed by 1400 | Submission Open
Keywords: hematology; artificial intelligence/AI; machine learning/ML; innovation; hemostasis; thrombosis; diagnostics; prog-nosis; laboratory automation; clinical decision support; precision medicine; big data; digital pathology
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Surgical Management of Hip Disorders: From Childhood Diseases to Total Hip Arthroplasty
edited by Sébastien Lustig and Moussa Hamadouche
submission deadline 30 Mar 2027 | Viewed by 28 | Submission Open
Keywords: hip; pathology; arthroplasty; primary; revision
(This special issue belongs to the Section Orthopedics)
The Wide World of Antinuclear Antibodies (ANA)-Associated Disorders: Patterns, Clinical Phenotypes, Comorbidities, and Impact submission deadline 31 Mar 2027 | 2 articles | Viewed by 2410 | Submission Open
Keywords: antinuclear antibodies (ANA); ANA-associated disorders; clinical phenotypes; ANA patterns; lupus, Sjögren’s disease, systemic sclerosis, idiopathic inflammatory myopathies, comorbidities; connective tissue diseases; overlap syndromes; undifferentiated connective tissue disease; risk stratification; patient-centered management
(This special issue belongs to the Section Immunology & Rheumatology)
Aortic Surgery—Back to the Roots and Looking to the Future
edited by Ezin Deniz and
submission deadline 31 Mar 2027 | 1 articles | Viewed by 1453 | Submission Open
Keywords: aortic surgery; hybrid and endovascular innovations; perioperative management; cerebral and organ protection; biomaterials; translational cardiovascular research; imaging in aortic disease; long-term outcomes; cardiovascular surgery
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Cutaneous and Systemic Lupus Erythematosus: Diagnosis, Treatment, and Comorbidities
edited by Magdalena Spałkowska and Joanna Kosałka-Węgiel
submission deadline 31 Mar 2027 | 1 articles | Viewed by 728 | Submission Open
Keywords: systemic lupus erythematosus; cardiovascular; Raynaud’s; cutaneous lupus erythematosus; autoimmune diseases
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Applications and Advances in Arthroscopic, Endoscopic, and Minimally Invasive Techniques in Orthopaedics
edited by Stylianos Kapetanakis
submission deadline 31 Mar 2027 | 1 articles | Viewed by 538 | Submission Open
Keywords: arthroscopy; endoscopic surgery; minimally invasive surgery; orthopaedic surgery; sports medicine; spine surgery; surgery; robotics
(This special issue belongs to the Section Orthopedics)
Clinical Advances in Coronary Artery Bypass Grafting
edited by and Mirko Doss
submission deadline 31 Mar 2027 | 1 articles | Viewed by 453 | Submission Open
Keywords: coronary artery bypass grafting; CABG; myocardial revascularization; multiarterial grafting; conduit selection; off-pump CABG; on-pump CABG; anaortic CABG; no-touch technique; minimally invasive coronary surgery; endo-scopic coronary surgery; robot-assisted coronary surgery; hybrid coronary revascularization; graft patency; perioper-ative outcomes; cardiac surgery; cardiovascular innovation
(This special issue belongs to the Section Cardiovascular Medicine)
Interventional Cardiology: Evolving Evidence and Emerging Horizons
edited by
submission deadline 31 Mar 2027 | Viewed by 394 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; drug-coated balloon; intravascular imaging; fractional flow reserve; transcatheter aortic valve implantation; transcatheter mitral valve repair; clinical outcomes
(This special issue belongs to the Section Cardiology)
JSOPB 2025–2026 Congress Special Issue—Update on Organ Preservation and Transplantation submission deadline 31 Mar 2027 | Viewed by 240 | Submission Open
Keywords: organ preservation; transplantation; pharmacology; clinical engineering; stem cell therapy
(This special issue belongs to the Section General Surgery)
Interplay of Motility, Microbiota, and Function: New Insights into GI Disorders, IBS, and SIBO
edited by Tsachi Tsadok Perets
submission deadline 1 Apr 2027 | 1 articles | Viewed by 1038 | Submission Open
Keywords: gastrointestinal motility; irritable bowel syndrome (IBS); small intestinal bacterial overgrowth (SIBO); gut microbiota; functional gastrointestinal disorders
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Pediatric Gastrointestinal and Nutritional Disorders submission deadline 3 Apr 2027 | Viewed by 208 | Submission Open
Keywords: gastrointestinal; malnutrition; obesity; nutrition; pancreas; cystic fibrosis; epidemiology; eosinophilic esophagitis; liver disorders; endoscopy
(This special issue belongs to the Section Clinical Pediatrics)
Optimizing Colorectal Cancer Therapy
edited by Fernando Mendoza-Moreno
submission deadline 4 Apr 2027 | Viewed by 91 | Submission Open
Keywords: rectal cancer; colorectal surgery; neoadjuvant chemoradiotherapy; TNM staging; tumor deposits; minimally invasive surgery; multidisciplinary oncologic care
(This special issue belongs to the Section Oncology)
Clinical Research and Perspectives in Hepatobiliary Surgery and Liver Transplant submission deadline 4 Apr 2027 | Viewed by 74 | Submission Open
Keywords: hepatobiliary surgery; liver transplantation; hepatopancreatobiliary surgery; transplant oncology; machine perfusion; organ preservation; donation after circulatory death; extended-criteria donors; living donor liver transplantation; minimally invasive surgery; robotic surgery; hepatocellular carcinoma; cholangiocarcinoma; colorectal liver metastases; perioperative outcomes; patient-reported outcomes; precision medicine
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Exercise, Injury and Rehabilitation: Integrated Perspectives in Sports Medicine submission deadline 5 Apr 2027 | 8 articles | Viewed by 18731 | Submission Open
Keywords: sports medicine; biomechanics; injury prevention; exercise physiology; sports performance; load management; exercise prescription; return to play; recovery
(This special issue belongs to the Section Sports Medicine)
Emerging Therapeutic Strategies for Coronary and Structural Heart Disease
edited by
submission deadline 5 Apr 2027 | 1 articles | Viewed by 396 | Submission Open
Keywords: coronary artery disease; structural heart disease; transcatheter interventions; percutaneous coronary intervention; valvular heart disease; cardiovascular therapeutics; interventional cardiology
(This special issue belongs to the Section Cardiovascular Medicine)
Blood Pressure Disorders: Risk Assessment, Surveillance and Clinical Interventions
edited by
submission deadline 7 Apr 2027 | Viewed by 323 | Submission Open
Keywords: hypertension; secondary hypertension; hypotension; target organ damage; hypertension phenotypes; hypertension emergency; hypertension urgency; microangiopathy; macroangiopathy; endothelial dysfunction; hypovolaemia; cardiogenic shock; dysautonomia
(This special issue belongs to the Section Cardiovascular Medicine)
Management of Congenital Heart Disease (CHD)
edited by Sarah Nordmeyer and Marie Schafstedde
submission deadline 10 Apr 2027 | 6 articles | Viewed by 6386 | Submission Open
Keywords: congenital heart disease; imaging; diagnostics; surgical innovations; minimally invasive interventions
(This special issue belongs to the Section Cardiovascular Medicine)
Sports Cardiology: Current Clinical Status and Outlook into the Future
edited by Aakash Bavishi and Matthew W Martinez
submission deadline 10 Apr 2027 | 4 articles | Viewed by 3154 | Submission Open
Keywords: sports cardiology; athletes; cardiac imaging; hypertrophic cardiomyopathy; screening; electrocardiogram; electrophysiology; echocardiography; sudden cardiac death
(This special issue belongs to the Section Cardiology)
Clinical Advances in Cardiothoracic Anesthesiology
edited by
submission deadline 10 Apr 2027 | 3 articles | Viewed by 2999 | Submission Open
Keywords: cardiac anesthesiology; thoracic anesthesiology; precision medicine; prevention of organ dysfunction; mechanical circulatory support; minimally invasive surgery
(This special issue belongs to the Section Anesthesiology)
New Insights into Glaucoma: 2nd Edition
edited by and
submission deadline 10 Apr 2027 | 2 articles | Viewed by 2371 | Submission Open
Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)
(This special issue belongs to the Section Ophthalmology)
Clinical Updates on Acromegaly
edited by , Jowita Halupczok-Żyła, Aleksandra Gilis-Januszewska and Przemysław Witek
submission deadline 10 Apr 2027 | 2 articles | Viewed by 2089 | Submission Open
Keywords: acromegaly; GH; IGH-1; growth hormone-secreting pituitary adenoma; pituitary adenoma
(This special issue belongs to the Section Endocrinology & Metabolism)
Current Challenges and Perspectives in Aortic Valve Replacement
edited by , Quentin Fischer and David Del Val
submission deadline 10 Apr 2027 | 1 articles | Viewed by 1878 | Submission Open
Keywords: aortic valve replacement; transcatheter aortic valve implantation (TAVI); surgical aortic valve replacement; prosthesis–patient mismatch; structural heart disease; heart team; valve durability; coronary access; valve-in-valve
(This special issue belongs to the Section Cardiovascular Medicine)
Crohn’s Disease: Ongoing Challenges and Future Directions in Diagnosis and Monitoring
edited by Laura Maria Minordi and
submission deadline 10 Apr 2027 | Viewed by 145 | Submission Open
Keywords: Crohn’s disease; imaging; endoscopy; complications; advanced therapies; radiomic; surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Advances in Functional Diagnostics and Physiotherapy of Musculoskeletal Disorders submission deadline 10 Apr 2027 | Viewed by 110 | Submission Open
Keywords: functional diagnostics; physiotherapy; rehabilitation; musculoskeletal system; functional assessment; gait analysis; movement biomechanics; postural control; postural stability; muscle strength; muscle tone; digital technologies in rehabilitation; objective measurement methods
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Swallowing Disorders: Advancing Measurement Science in Dysphagia
edited by Phoebe Macrae
submission deadline 10 Apr 2027 | Viewed by 85 | Submission Open
Keywords: dysphagia; measurement science; outcome measurement; psychometrics; swallowing physiology; instrumental assessment; quantitative measurement; measurement methodology; biomarkers; patient-reported outcome measures (PROMs); artificial intelligence
(This special issue belongs to the Section Otolaryngology)
Advances in Musculoskeletal Rehabilitation and Functional Movement
edited by
submission deadline 13 Apr 2027 | 6 articles | Viewed by 6839 | Submission Open
Keywords: corrective exercise; functional training; biomechanics; resistance training; movement impairment; electromyography; muscle activation; musculoskeletal rehabilitation
(This special issue belongs to the Section Clinical Rehabilitation)
Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives: 2nd Edition
edited by and Nicola Virtuoso
submission deadline 15 Apr 2027 | 7 articles | Viewed by 6266 | Submission Open
Keywords: hypertension management; cardiovascular risk assessment; novel antihypertensive therapies; hypertension in pregnancy; hypertensive emergencies; cardiovascular disease prevention; pharmacological interventions for cardiovascular disease
(This special issue belongs to the Section Cardiovascular Medicine)
Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities
edited by Rami S Kantar
submission deadline 15 Apr 2027 | 5 articles | Viewed by 5042 | Submission Open
Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
New Perspectives and Innovations in Critical Illness submission deadline 15 Apr 2027 | 3 articles | Viewed by 2453 | Submission Open
Keywords: critical illness; intensive care; ECMO; hemodynamic management; shock physiology; cardiovascular support
(This special issue belongs to the Section Intensive Care)
Future-Proof Care for Patients with Kidney Stones
edited by and Oliver Wiseman
submission deadline 15 Apr 2027 | 3 articles | Viewed by 1508 | Submission Open
Keywords: effectiveness; resilience; prevention; care pathways; urolithiasis; kidney stones; PCNL; URS; ESWL; quality of life
(This special issue belongs to the Section Nephrology & Urology)
Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition
edited by Dario Giorgio and Dario Pasquale Mucciolo
submission deadline 15 Apr 2027 | 1 articles | Viewed by 839 | Submission Open
Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging
(This special issue belongs to the Section Ophthalmology)
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