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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Treatments for Vestibular Migraine
edited by
submission deadline 28 May 2026 | Viewed by 321 | Submission Open
Keywords: neuromodulation therapy; sympathetic nerve stimulation; CGRP-targeted therapy; dietary interventions; elimination diets; ketogenic diet; low-glycemic index diet; nutritional supplements; pathophysiology of vestibular migraine; clinical adoption of VM therapies
(This special issue belongs to the Section Otolaryngology)
Challenges in the Diagnosis and Treatment of Glaucoma
edited by
submission deadline 28 May 2026 | Viewed by 276 | Submission Open
Keywords: glaucoma diagnosis; glaucoma progression; glaucoma biomarkers; intraocular pressure (IOP) management; corneal hysteresis; machine learning in glaucoma detection; neuroprotection in glaucoma; surgery and laser therapy
(This special issue belongs to the Section Ophthalmology)
Spine Surgery Innovations: Treatments and Technologies
edited by and Tomoyuki Asada
submission deadline 29 May 2026 | Viewed by 445 | Submission Open
Keywords: AI; robotics; navigation; muscle preservation; minimally invasive surgery; motion preservation; alignment targets; implant materials; bone growth factors; custom-made implants
(This special issue belongs to the Section Orthopedics)
Pediatric Hearing Loss: Advances in Early Detection, Intervention and Family-Centered Care submission deadline 30 May 2026 | Viewed by 97 | Submission Open
Keywords: pediatric hearing loss; early intervention; early identification of language and communication disorders; develop-mental language disorders; predictors of outcomes; newborn hearing screening; pediatric audiology
(This special issue belongs to the Section Otolaryngology)
Clinical Perspectives on Women’s Reproductive Health: Challenges and Management Strategies
edited by
submission deadline 31 May 2026 | 8 articles | Viewed by 18546 | Submission Open
Keywords: endometriosis; ovarian endometrioma; polycystic ovary syndrome; reproductive health; cervical; postmenopausal women; hormone replacement therapy; sarcopenia
(This special issue belongs to the Section Obstetrics & Gynecology)
Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management
edited by and Sérgio Laranjo
submission deadline 31 May 2026 | 5 articles | Viewed by 5951 | Submission Open
Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Updates on Prosthodontics
edited by and Carla Fons-Badal
submission deadline 31 May 2026 | 3 articles | Viewed by 3450 | Submission Open
Keywords: dental prosthesis; dental implants; gingival aesthetics; gingival treatment; dental aesthetics; dental ceramics; BOPT; surgical periodontal treatment
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Cardiovascular Magnetic Resonance Imaging: Precise Diagnosis and Therapeutic Guidance
edited by Radu Andy Sascau and
submission deadline 31 May 2026 | 2 articles | Viewed by 1786 | Submission Open
Keywords: cardiac magnetic resonance; cardiomyopathy; tissue characterization; stress perfusion; 4D flow; heart failure; ischemic heart disease; multi-modality imaging; valvular heart disease; T1 mapping; T2 mapping; myocarditis
(This special issue belongs to the Section Cardiovascular Medicine)
Advances in Male Infertility: Diagnosis, Management and ART Integration
edited by Despoina Mavrogianni and Sofoklis Stavros
submission deadline 31 May 2026 | Viewed by 1243 | Submission Open
Keywords: male infertility; assisted reproductive technologies (ART); intracytoplasmic sperm injection (ICSI); genetic testing; hormonal profiling; seminal biomarkers; sperm retrieval techniques; sperm selection; stem cell therapy; gene editing; reproductive endo-crinology; early pregnancy; implantation failure; recurrent miscarriage
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Early Prevention and Diagnosis of Atherosclerosis: From Clinical Progression to Patient Management submission deadline 31 May 2026 | 1 articles | Viewed by 996 | Submission Open
Keywords: atherosclerosis; atherothrombotic molecular pathways; cardiovascular risk; monitoring of goals; pharmacological and non-pharmacological prevention; carotid and peripheral interventions
(This special issue belongs to the Section Cardiovascular Medicine)
New Insights into Hepato-Biliary Diseases: Translating Science into Practice submission deadline 31 May 2026 | Viewed by 363 | Submission Open
Keywords: hepato-biliary diseases; biomarkers; drug discovery; liver organoids and microfluidics; pathogenesis
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Personalized Management of Abdominal Surgery and Complications
edited by Ioannis Mantzoros and
submission deadline 31 May 2026 | Viewed by 138 | Submission Open
Keywords: personalized medicine; abdominal surgery; complications; emergency; innovative surgery
(This special issue belongs to the Section General Surgery)
Clinical Advances and Contemporary Applications of Echocardiography
edited by
submission deadline 31 May 2026 | Viewed by 110 | Submission Open
Keywords: echocardiography; speckle-tracking; three-dimensional; Doppler; cardiac; valve; vasculature
(This special issue belongs to the Section Cardiovascular Medicine)
Applications of Artificial Intelligence (AI) in Surgery submission deadline 31 May 2026 | Viewed by 88 | Submission Open
Keywords: artificial intelligence; machine learning; surgical robotics; computer vision; predictive analytics; surgical decision support; perioperative care; surgical outcomes; digital surgery
(This special issue belongs to the Section General Surgery)
Current Advances and Future Challenges in Heart Transplantation
edited by
submission deadline 31 May 2026 | Viewed by 86 | Submission Open
Keywords: heart transplantation; indication; surgical techniques; preoperative care; immunosuppressive regimens; mechanical circulatory support; donor assessment and management; cardiac donation after circulatory death; ex vivo machine perfusion; normothermic regional perfusion; cardiac xenotransplantation
(This special issue belongs to the Section Cardiology)
Advances in the Management of Cancer Pain
edited by Wojciech Leppert
submission deadline 31 May 2026 | Viewed by 59 | Submission Open
Keywords: analgesia; analgesics; cancer patients; chronic pain; pain in cancer patients; pain assessment; non-opioids; opioid analgesics; adjuvant analgesics; non-pharmacology methods of pain management
(This special issue belongs to the Section Epidemiology & Public Health)
Aortic Surgery—Back to the Roots and Looking to the Future
edited by Ezin Deniz and
submission deadline 31 May 2026 | Viewed by 57 | Submission Open
Keywords: aortic surgery; hybrid and endovascular innovations; perioperative management; cerebral and organ protection; biomaterials; translational cardiovascular research; imaging in aortic disease; long-term outcomes; cardiovascular surgery
(This special issue belongs to the Section Cardiovascular Medicine)
Diagnosis and Treatment of Pediatric Endocrine Disorders—Focus on Rare Conditions
edited by Sophia Sakka
submission deadline 1 Jun 2026 | Viewed by 1171 | Submission Open
Keywords: pediatric endocrinology; diabetes mellitus in children; bone metabolism disorders; clinical diagnosis; therapeutic strategies; skeletal dysplasias; rare endocrine conditions; pediatric type 1 diabetes; rickets management; genetic conditions; pediatric hormone therapy; achondroplasia
(This special issue belongs to the Section Endocrinology & Metabolism)
Orthodontics: State of the Art and Prospects
edited by Beatriz Tarazona-Álvarez and
submission deadline 5 Jun 2026 | 1 articles | Viewed by 1843 | Submission Open
Keywords: digital orthodontics; clear aligners; 3D printing; accelerated orthodontics; digital treatment plan; nanotechnology
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Latest Research on Male Infertility submission deadline 5 Jun 2026 | 2 articles | Viewed by 1268 | Submission Open
Keywords: testis; sperm; seminal plasma; spermatogenesis; fertilization; omics; proteomics; oxidative stress; sperm DNA fragmentation; varicocele; male infertility; testicular cancer; infertility management; ART
(This special issue belongs to the Section Reproductive Medicine & Andrology)
New Insights on Pharmacologic and Non-Pharmacologic Therapy of Advanced Heart Failure
edited by
submission deadline 5 Jun 2026 | Viewed by 72 | Submission Open
Keywords: advanced heart failure (AHF); mechanical circulatory support systems; heart transplantation (HTx); immunosuppression; cardiac allograft rejections
(This special issue belongs to the Section Cardiology)
Sjogren’s Syndrome: Clinical Advances and Insights
edited by David A. Isenberg
submission deadline 7 Jun 2026 | 1 articles | Viewed by 252 | Submission Open
Keywords: xerostomia; xerophthalmia; non-Hodgkins lymphoma; autoimmune rheumatic diseases; Sjogren’ s syndrome
(This special issue belongs to the Section Immunology & Rheumatology)
Clinical Research and Personalized Medicine in Inflammatory Bowel Disease
edited by and Loris Riccardo Lopetuso
submission deadline 10 Jun 2026 | 4 articles | Viewed by 5500 | Submission Open
Keywords: inflammatory bowel disease (IBD); personalized medicine; precision medicine; Crohn’ s disease; ulcerative colitis; targeted therapy; artificial intelligence
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Perspectives of Vascular and Endovascular Surgeries submission deadline 10 Jun 2026 | 2 articles | Viewed by 2568 | Submission Open
Keywords: vascular surgery; varicose veins; abdominal aortic aneurysms; carotid disease; peripheral arterial disease
(This special issue belongs to the Section Vascular Medicine)
Regional Anesthesia and Pain Management: Mastering Clinical Art for Optimal Patient Satisfaction
edited by
submission deadline 10 Jun 2026 | 2 articles | Viewed by 2296 | Submission Open
Keywords: regional anesthesia; pain management; ultrasound-guided nerve blocks; fascial plane blocks; multimodal analgesia; postoperative analgesia; chronic pain management; opioid-sparing strategies; non-opioid analgesics; patient satisfaction; anesthesia techniques; perioperative care; pain interventions; nerve block techniques; clinical outcomes
(This special issue belongs to the Section Anesthesiology)
Cardiovascular Health: Advances in Prevention, Treatment and Innovative Therapies
edited by
submission deadline 10 Jun 2026 | Viewed by 1368 | Submission Open
Keywords: atherosclerosis; dyslipidemia; cardiac risk factors; premature ASCVD; left atrium function; atrial fibrillation; coronary imaging
(This special issue belongs to the Section Cardiovascular Medicine)
Diabetes Mellitus and Emerging Health Challenges: A Multidisciplinary Perspective
edited by Katarzyna A. Majewska and
submission deadline 10 Jun 2026 | 3 articles | Viewed by 1018 | Submission Open
Keywords: diabetes mellitus; type 1 diabetes; type 2 diabetes; diabetic complications; prediabetes; diabetes treatment; autoimmune diabetes
(This special issue belongs to the Section Endocrinology & Metabolism)
Surgical Management of Maxillofacial Fractures and Reconstruction of Facial Deformities
edited by , and Francesco Arcuri
submission deadline 10 Jun 2026 | 2 articles | Viewed by 975 | Submission Open
Keywords: head and neck reconstruction; facial fractures; minimally invasive treatments; facial reconstruction; bioengineering in head and neck disorders; CAD/CAM in maxillo facial trauma and deformities
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Clinical Outcomes Improvement and Perioperative Management of Surgical Patients: 3rd Edition submission deadline 10 Jun 2026 | 2 articles | Viewed by 555 | Submission Open
Keywords: clinical outcomes; surgery; quality; quality of life; quality improvement; postoperative; morbidity; postoperative care
(This special issue belongs to the Section General Surgery)
Exploring Cardiomyopathy: Comprehensive Guide to Causes, Symptoms and Care
edited by
submission deadline 10 Jun 2026 | Viewed by 316 | Submission Open
Keywords: cardiomyopathy; heart failure; genetics; hypertrophic cardiomyopathy; dilated cardiomyopathy; left ventricular noncompaction; pediatric cardiomyopathies; cardiac imaging
(This special issue belongs to the Section Cardiology)
Cardiac Arrest and Postcardiac Arrest Care: State of the Art and Future Directions
edited by and Soheil Saadat
submission deadline 10 Jun 2026 | Viewed by 91 | Submission Open
Keywords: out-of-hospital cardiac arrest; cardiopulmonary resuscitation; postcardiac arrest syndrome; postcardiac arrest care; survival; neurologic outcomes
(This special issue belongs to the Section Emergency Medicine)
Clinical and Diagnostic Strategies for Glioma Treatment
edited by Aleksandrs Krigers and Egils Valeinis
submission deadline 10 Jun 2026 | Viewed by 91 | Submission Open
Keywords: glioma; glioblastoma; astrocytoma; oligodendroglioma; IDH; neuro-oncology; neurosurgery; radiotherapy; neuropathology; diagnostics; treatment
(This special issue belongs to the Section Clinical Neurology)
New Technologies for Personalized Medicine in Head and Neck Surgery submission deadline 10 Jun 2026 | Viewed by 76 | Submission Open
Keywords: personalized medicine; head and neck surgery; 3D printing; surgical navigation; artificial intelligence; computer-assisted surgery; regenerative medicine; precision oncology; craniofacial reconstruction; biomaterials; virtual surgical planning; genomics and proteomics; tissue engineering; functional rehabilitation
(This special issue belongs to the Section Otolaryngology)
Cardiomyopathy: Diagnosis and Therapeutic Advances
edited by Ilaria Dentamaro and Annagrazia Cecere
submission deadline 10 Jun 2026 | Viewed by 61 | Submission Open
Keywords: cardiomiopathy; cardiac magnetic resonance (CMR); advanced echocardiography; heart failure; hypertrophic cardiomyopathy
(This special issue belongs to the Section Cardiology)
Clinical Advancements in Intraocular Lens Power Calculation Methods
edited by and Thomas Kohnen
submission deadline 12 Jun 2026 | 2 articles | Viewed by 2425 | Submission Open
Keywords: emmetropia; IOL power calculation; effective lens position; refractive lens exchange; IOL; refractive surgery; biometry
(This special issue belongs to the Section Ophthalmology)
Systemic Sclerosis: State of the Art and Future Directions
edited by Antonino Mazzone and
submission deadline 12 Jun 2026 | Viewed by 66 | Submission Open
Keywords: systemic sclerosis; current knowledge; advanced knowledge; vasculopathy; interstitial lung disease; pulmonary arterial hypertension; perspectives; novelties
(This special issue belongs to the Section Dermatology)
Evidence-Based Clinical Management of Orthopaedic Trauma: 25 Years in Retrospect, and a Forecast of 25 Years to Come
edited by Dirk Stengel and
submission deadline 15 Jun 2026 | 5 articles | Viewed by 11170 | Submission Open
Keywords: evidence-based medicine; orthopaedic surgery; clinical trials; systematic reviews; patient outcomes; multiple trauma; artificial intelligence; injuries
(This special issue belongs to the Section Orthopedics)
Coronary Heart Disease: Causes, Diagnosis and Management
edited by
submission deadline 15 Jun 2026 | 3 articles | Viewed by 10197 | Submission Open
Keywords: coronary heart disease; coronary revascularization; coronary artery disease; ischemic heart disease; atherosclerosis
(This special issue belongs to the Section Cardiology)
Aortic Pathologies: Aneurysm, Atherosclerosis and More
edited by Alexander Gombert and Panagiotis Doukas
submission deadline 15 Jun 2026 | 4 articles | Viewed by 8470 | Submission Open
Keywords: aorta; aortic aneurysm; thoracoabdominal aortic aneurysm; fenestrated endovascular aortic repair (FEVAR); branched endovascular aortic repair (BEVAR); spinal cord ischemia; coral reef aorta; surgery; endovascular aortic surgery
(This special issue belongs to the Section Cardiovascular Medicine)
Male Sexual and Reproductive Health: Clinical Aspects, Metabolic Profile, Environmental Factors and Lifestyle: 2nd Edition
edited by
submission deadline 15 Jun 2026 | 3 articles | Viewed by 8209 | Submission Open
Keywords: male sexual dysfunction; reproductive health; erectile dysfunction; premature ejaculation; infertility; epidemiology; causes; diagnosis; treatments; environmental factors; lifestyle
(This special issue belongs to the Section Reproductive Medicine & Andrology)
Advances in the Diagnosis and Treatment of Glaucoma
edited by
submission deadline 15 Jun 2026 | 4 articles | Viewed by 5778 | Submission Open
Keywords: OCT; glaucoma; MIGS; neuroprotection; drug delivery systems; artificial intelligence; pharmacologic agents; per-sonalized medicine
(This special issue belongs to the Section Ophthalmology)
Scoliosis: Advances in Diagnosis and Management
edited by Michal Latalski
submission deadline 15 Jun 2026 | 3 articles | Viewed by 5681 | Submission Open
Keywords: scoliosis; adolescent idiopathic scoliosis; adult scoliosis; congenital scoliosis; neuromuscular scoliosis; diagnosis; imaging; treatment; surgery; bracing; rehabilitation; patient-reported outcomes; quality of life
(This special issue belongs to the Section Orthopedics)
Arthroplasty: Advances in Surgical Techniques and Patient Outcomes—2nd Edition
edited by Senthil Sambandam
submission deadline 15 Jun 2026 | 2 articles | Viewed by 3307 | Submission Open
Keywords: hip arthroplasty; knee arthroplasty; hip fractures; arthroplasty; osteoarthritis; knee arthroscopy; joint replacement
(This special issue belongs to the Section Orthopedics)
Key Advances in the Treatment of the Critically Ill: 3rd Edition submission deadline 15 Jun 2026 | 2 articles | Viewed by 2359 | Submission Open
Keywords: respiration; artificial ventilation; prone positioning; respiratory distress syndrome; respiratory insufficiency; cardiac arrest; induced hypothermia; amiodarone; vasopressin; steroids; epinephrine; trauma; injuries; tranexamic acid; sepsis; antibiotics; extracorporeal membrane oxygenation; extracorporeal CPR; blood purification
(This special issue belongs to the Section Intensive Care)
Blood Cancers: Current Status and Future Challenges
edited by and Massimo Breccia
submission deadline 15 Jun 2026 | 1 articles | Viewed by 2215 | Submission Open
Keywords: acute myeloid leukemia; hematology; leukemia; venetoclax; blood disorders
(This special issue belongs to the Section Hematology)
Emergency Surgery: Clinical Updates and New Perspectives
edited by
submission deadline 15 Jun 2026 | 1 articles | Viewed by 2163 | Submission Open
Keywords: emergency surgery; trauma surgery; acute abdomen; hernia emergencies; surgical decision making; perioperative care; damage control surgery; emergency management; critical care surgery; multidisciplinary approach
(This special issue belongs to the Section Emergency Medicine)
Thoracic Surgery: Current Practice and Future Directions: 2nd Edition
edited by
submission deadline 15 Jun 2026 | 3 articles | Viewed by 1715 | Submission Open
Keywords: NSCLC; mediastinum; thymoma; esophageal disease; immunotherapy; new technologies; minimally invasive surgery; VATS; RATS
(This special issue belongs to the Section Respiratory Medicine)
Gender Differences and Diversity in the Treatment of Gastric Cancer and Other Malignancies
edited by Claus Schildberg and Frank Meyer
submission deadline 15 Jun 2026 | 2 articles | Viewed by 1688 | Submission Open
Keywords: gastric cancer; other cancers; other treatment; gender differences; diversity; new challances
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Updates on Valvular Heart Diseases: A New Era in Personalized Treatment
edited by Massimiliano Mariani
submission deadline 15 Jun 2026 | 2 articles | Viewed by 1504 | Submission Open
Keywords: valvular heart disease; structural heart intervention; imaging in valve disease; interventional echocardiography; minimally invasive cardiac surgery; aortic valve intervention; tricuspid valve intervention; valve intervention in GUCH; patient-specific therapy; advanced diagnostic techniques; gutting-edge cardiac imaging; catheter-based interventions; innovative cardiac therapies
(This special issue belongs to the Section Cardiology)
Perioperative Management in Thoracic Surgery: Current Advances and Future Perspectives submission deadline 15 Jun 2026 | 1 articles | Viewed by 1011 | Submission Open
Keywords: thoracic surgery; perioperative care; ERAS; minimally invasive surgery; interventional pulmonology; preoperative assessment; postoperative management; surgical outcomes; multidisciplinary approach; technology in surgery
(This special issue belongs to the Section Respiratory Medicine)
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