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Orthodontics: State of the Art and Prospects

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 318

Special Issue Editors


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Guest Editor
Department of Orthodontics, Faculty of Medicine and Dentistry, Universidad de Valencia, Valencia, Spain
Interests: 3D facial analyis; 3D cephalometry; accelerated orthodontics; mini screws; digital planning

E-Mail Website
Guest Editor
Department of Orthodontics, Faculty of Medicine and Dentistry, Universidad de Valencia, Valencia, Spain
Interests: 3D facial analyis; 3D cephalometry; accelerated orthodontics; mini screws; digital planning

Special Issue Information

Dear Colleagues,

In recent years, orthodontics has made remarkable advances thanks to digital technology and new materials. Today, clear aligners, lingual orthodontics and self-ligating brackets have improved the aesthetics and efficiency of treatment. Tools such as artificial intelligence, intraoral scanners, 3D cameras, CBCT or 3D printing allow for more accurate diagnoses and personalised treatment plans. In addition, accelerated orthodontics and bioengineering aim to reduce treatment times and improve the patient experience.

As the future of orthodontics points toward less invasive approaches, nanotechnology, and treatments based on big data, it is imperative that we continue to research and disseminate knowledge in this field. Therefore, in this Special Issue, we invite you to share your research in our journal and contribute to the growth of the scientific community and the development of new solutions for dental health. Your participation is key to continued innovation.

Prof. Dr. Beatriz Tarazona-Álvarez
Prof. Dr. Natalia Zamora-Martínez
Guest Editors

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Keywords

  • digital orthodontics
  • clear aligners
  • 3D printing
  • accelerated orthodontics
  • digital treatment plan
  • nanotechnology

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Published Papers (1 paper)

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16 pages, 1128 KiB  
Systematic Review
The Influence of Diabetes on Orthodontic Treatment: A Systematic Review of the Clinical Considerations and Challenges in Response
by Paula García-Rios, Francisco Javier Rodríguez-Lozano, Julia Guerrero-Gironés, Miguel R. Pecci-Lloret, Ricardo E. Oñate-Sánchez and Nuria Pérez-Guzmán
J. Clin. Med. 2025, 14(14), 4879; https://doi.org/10.3390/jcm14144879 - 9 Jul 2025
Viewed by 160
Abstract
Background/Objectives: Diabetes mellitus is defined as a group of metabolic diseases characterized by chronically elevated blood glucose levels. This condition influences the course of orthodontic treatment, as it affects various clinical aspects of the patient that must be taken into consideration prior to [...] Read more.
Background/Objectives: Diabetes mellitus is defined as a group of metabolic diseases characterized by chronically elevated blood glucose levels. This condition influences the course of orthodontic treatment, as it affects various clinical aspects of the patient that must be taken into consideration prior to initiation. Therefore, achieving adequate control and management of diabetic patients undergoing orthodontic therapy is essential. This article presents a qualitative synthesis of studies addressing how diabetes affects orthodontic treatments, emphasizing the importance of understanding the necessary considerations prior to initiating treatment and how to manage potential complications. Methods: This systematic review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. A database search was performed on 5 May 2025, in PubMed, Scopus, Scielo, and The Cochrane Library, using terms related to “diabetes mellitus” and “orthodontic treatments”. Studies meeting the search criteria were included, particularly those that were published in the past ten years and reported on the influence of diabetes on orthodontic treatment. The quality of the case–control studies was assessed using the Newcastle–Ottawa Scale (NOS); for cross-sectional studies, the Joanna Briggs Institute (JBI) critical appraisal checklist was used; and for experimental studies, the SYRCLE’s Risk of Bias Tool was applied. Results: Fourteen studies ultimately met the inclusion criteria. The evidence showed that diabetes increases gingival bleeding due to elevated levels of advanced glycation end-products (AGEs) and pro-inflammatory cytokines; reduces the efficiency of tooth movement; increases root resorption and affects bone remodeling; and compromises both periodontal and pulpal responses, thereby hindering tissue regeneration. It was also observed that the use of insulin or antidiabetic agents such as metformin may partially mitigate these adverse effects. Conclusions: This systematic review reveals a clear relationship between diabetes and various clinical aspects that influence the progression of orthodontic treatments. Nonetheless, further studies are needed to better understand the impact of this systemic condition on dental treatment outcomes. Full article
(This article belongs to the Special Issue Orthodontics: State of the Art and Prospects)
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