Clinical Perspectives on Women’s Reproductive Health: Challenges and Management Strategies

Dear Colleagues,

In recent years, the prevalence of gynecological conditions such as endometriosis and polycystic ovary syndrome (PCOS) has shown a marked increase among women of reproductive age. These chronic disorders significantly impact reproductive function and long-term metabolic health. Recent advancements in clinical and translational research have led to the development of fertility-preserving strategies in endometriosis, including refined surgical techniques and tailored hormonal therapies. Similarly, evolving insights into the heterogeneity of PCOS have contributed to improved diagnostic algorithms and individualized treatment approaches.

In parallel, increasing attention is being given to reproductive aging and the health of postmenopausal women, particularly regarding the impact of estrogen deficiency on sarcopenia and overall metabolic resilience. Evidence supporting the role of hormone replacement therapy (HRT) in maintaining musculoskeletal health continues to grow, warranting further exploration through well-designed clinical studies.

This Special Issue aims to highlight current challenges and evolving perspectives in women’s reproductive health, with a focus on the increasing prevalence of endometriosis and PCOS, recent advances in therapeutic approaches, and the implications of hormonal changes in postmenopausal health, in light of the most up-to-date clinical evidence.

Prof. Dr. Seok Kyo Seo
Guest Editor

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