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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advance in Bariatric Surgery

edited by

Lidia Castagneto Gissey

submission deadline 25 Jul 2026 | Viewed by 66 | Submission Open

Keywords: bariatric surgery; metabolic surgery; minimally invasive surgery; robotic surgery; endoscopic bariatric procedures; obesity management; type 2 diabetes remission; perioperative care; long-term outcomes; enhanced recovery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Complications Related to Coronary Artery Disease and Secondary Prevention Strategies

edited by Nazanin Rajai

submission deadline 25 Jul 2026 | Viewed by 63 | Submission Open

Keywords: coronary artery disease; complications; secondary prevention; myocardial infarction; cardiovascular risk; heart failure; arrhythmias; imaging; biomarkers; cardiovascular pharmacotherapy

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Application of Endoscopic Submucosal Dissection in Malignant Gastrointestinal Tumors and Precursors—2nd Edition

edited by

Rainer Schöfl

and

Reinhold Függer

submission deadline 25 Jul 2026 | Viewed by 60 | Submission Open

Keywords: endoscopy; endoscopic submucosal dissection; endoscopic surgery; laparoscopic surgery; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care

edited by Alen Protić and

Vlatka Sotosek

submission deadline 25 Jul 2026 | Viewed by 57 | Submission Open

Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis

(This special issue belongs to the Section Intensive Care)

Hearing Loss Management in Children: Guidelines and Interventions

edited by Lone Percy-Smith

submission deadline 25 Jul 2026 | Viewed by 53 | Submission Open

Keywords: early intervention for populations with HL; emerging new generations of persons with HL; quality assurance of interventions for populations with HL; self-assessments of quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Obstructive Sleep Apnea: Advances in Clinical Diagnosis and Management

edited by

Gonzalo Labarca

submission deadline 25 Jul 2026 | Viewed by 47 | Submission Open

Keywords: obstructive sleep apnea; sleep disorder breathing; central apnea; apnea– hypopnea index; precision medicine

(This special issue belongs to the Section Respiratory Medicine)

Current Advances and Future Perspectives in Cardiac Arrest and Cardiogenic Shock

edited by Giulia Maj

submission deadline 25 Jul 2026 | Viewed by 45 | Submission Open

Keywords: cardiogenic shock; left ventricular unloading; biomarkers; recovery; cardiac arrest

(This special issue belongs to the Section Emergency Medicine)

Interaction Between Systemic Diseases and Oral Diseases: 2nd Edition

edited by

Henk S. Brand

submission deadline 25 Jul 2026 | Viewed by 42 | Submission Open

Keywords: medical dental interaction; saliva; xerostomia; diagnostics; inflammatory bowel disease; cancer survivors; dental erosion; Sjö gren’ s disease; liver transplantation

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Cardiac Electrophysiology: New Insights and Future Directions: 2nd Edition

edited by

Michael Spartalis

submission deadline 25 Jul 2026 | Viewed by 35 | Submission Open

Keywords: catheter ablation; pulsed-field ablation; conduction-system pacing; arrhythmias; implantable cardiac devices; leadless pacing; mapping technologies; digital health; artificial intelligence; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Updates in the Diagnosis, Imaging, and Treatment of Retinal and Macular Diseases

edited by

Makoto Inoue

submission deadline 26 Jul 2026 | Viewed by 73 | Submission Open

Keywords: retinal diseases; macular degeneration; diagnostic imaging; OCT/OCTA; artificial intelligence; deep learning; clinical ophthalmology; gene therapy; treatment innovations

(This special issue belongs to the Section Ophthalmology)

Clinical Diagnosis and Treatment Strategies in Sjogren's Disease (SjD)

edited by

Nancy L. Carteron

Ava Wu

and Nancy McNamara

submission deadline 29 Jul 2026 | Viewed by 61 | Submission Open

Keywords: Sjogren; Sjogren’ s disease; lymphocytic tissue infiltration; interdisciplinary care; pathogenesis; caries; corneal erosions; autoimmunity; lymphoproliferative (or lymphoma)

(This special issue belongs to the Section Immunology & Rheumatology)

Improving Outcomes in Systemic Lupus Erythematosus: Latest Advances and Prospects in Relation to Comorbidity, Damage, and Quality of Life

edited by

Oshrat E. Tayer-Shifman

and Shaye Kivity

submission deadline 30 Jul 2026 | Viewed by 90 | Submission Open

Keywords: systemic lupus erythematosus; comorbidities; outcome measures; damage accrual; quality of life; cognitive im-pairment; infections and vaccination; treat-to-target; digital biomarkers

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Insights and Applications in Cardiac Electrophysiology

edited by

Alberto Preda

and Fabrizio Guarracini

submission deadline 30 Jul 2026 | Viewed by 71 | Submission Open

Keywords: atrial fibrillation; catheter ablation; transvenous lead extraction; left atrial appendage occlusion; heart failure; subcutaneous ICD; extravascular ICD; conduction system pacing; cardiac electrophysiology; cardiac rhythm disorders; arrhythmia mapping; supraventricular arrhythmias; ventricular arrhythmias; cardiomyopathies; implantable cardiac devices; minimally invasive devices; left atrial appendage closure; personalized arrhythmia care; clinical management; innovative electrophysiological techniques

(This special issue belongs to the Section Cardiology)

Clinical and Laboratory Applications of Artificial Intelligence in Haematology

edited by

Emmanuel Favaloro

and Bingwen Eugene Fan

submission deadline 30 Jul 2026 | Viewed by 70 | Submission Open

Keywords: hematology; artificial intelligence/AI; machine learning/ML; innovation; hemostasis; thrombosis; diagnostics; prog-nosis; laboratory automation; clinical decision support; precision medicine; big data; digital pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)

Endoscopic Management of Pancreaticobiliary Diseases

edited by

Kamran Ayub

submission deadline 30 Jul 2026 | Viewed by 59 | Submission Open

Keywords: pancreaticobiliary endoscopy; endoscopic ultrasound (EUS); endoscopic retrograde cholangiopancreatography (ERCP); biliary drainage; gallbladder drainage; lumen-opposing metal stents; cholangioscopy; pancreatoscopy; confocal laser endomicroscopy; pancreatic cysts; molecular diagnostics; lithotripsy (electrohydraulic and laser); radiofrequency ablation (RFA); photodynamic therapy (PDT); pancreatic and biliary tumors; interventional endoscopy; altered anatomy access; diagnostic and therapeutic endoscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Integrated Assessment and Management of Heart Failure Syndromes

edited by Damiano Magrì and Emiliano Fiori

submission deadline 30 Jul 2026 | Viewed by 55 | Submission Open

Keywords: heart failure; functional capacity; multimodality assessment; advanced imaging; coronary and structural interventions; device therapies

(This special issue belongs to the Section Cardiology)

Innovations in Elbow and Shoulder Surgery: Techniques, Outcomes, and Rehabilitation

edited by Andrea Celli

submission deadline 30 Jul 2026 | Viewed by 47 | Submission Open

Keywords: orthopedic; elbow surgery; shoulder surgery; infection; nonunion; malunion; ligaments injuries; tendon injuries; el-bow and shoulder replacement; arthroscopy

(This special issue belongs to the Section Orthopedics)

Effects of Exercise Training on Physiological and Functional Outcomes in Age and Frailty

edited by

Dihogo Gama de Matos

and

Rodrigo Villar

submission deadline 30 Jul 2026 | Viewed by 36 | Submission Open

Keywords: exercise training ; older adults ; frailty ; cardiovascular system ; autonomic system ; quality of life ; healthy aging ; functional capacity

(This special issue belongs to the Section Geriatric Medicine)

Clinical Application of Physical Therapy in Neurorehabilitation: 3rd Edition

edited by

Sofia Straudi

and

Roberto Cano de la Cuerda

submission deadline 31 Jul 2026 | 2 articles | Viewed by 673 | Submission Open

Keywords: physical therapy; technology-aided rehabilitation; exercise; neurorehabilitation; neuroplasticity; engagement; self-management

(This special issue belongs to the Section Clinical Rehabilitation)

Psychogerontology: Psychological Insights into Aging

edited by Sónia Martins and

Sara Lima

submission deadline 31 Jul 2026 | Viewed by 491 | Submission Open

Keywords: psychogerontology; aging process; adjustment; mental health; psychopatology; personality; emotions; well-being; spir-ituality; quality of life; caregiving; psychogerontology assessment and interventions

(This special issue belongs to the Section Mental Health)

Neuro-Psychiatric Disorders: Updates on Diagnosis and Treatment—2nd Edition

edited by

Georgios Floros

submission deadline 31 Jul 2026 | Viewed by 49 | Submission Open

Keywords: neuropsychiatric disorder; diagnosis; treatment; neurobiology; organic psychiatry

(This special issue belongs to the Section Mental Health)

Breakthroughs in the Treatment of Colorectal Cancer

edited by Laura Fortuna and

Andrea Bottari

submission deadline 31 Jul 2026 | Viewed by 49 | Submission Open

Keywords: colorectal cancer; targeted therapy; minimally invasive surgery; immune– oncology integration; enhanced recovery protocols; multidisciplinary care

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Future Direction of Medical Imaging in Hepato-Bilio-Pancreatic Oncology: Challenges and Opportunities

edited by

Nicolò Brandi

submission deadline 31 Jul 2026 | Viewed by 44 | Submission Open

Keywords: MRI; CT; molecular imaging; radiomics; imaging; radiogenomics; precision medicine; outcome prediction; cholangiocarcinoma; pancreatic cancer; imaging biomarkers; treatment response

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Pulmonary Hypertension: From Pathophysiology to Clinical Management

edited by

Dirk Bandorski

and

Lukas Ley

submission deadline 31 Jul 2026 | Viewed by 41 | Submission Open

Keywords: pulmonary hypertension; pulmonary arterial hypertension; chronic thromboembolic pulmonary hypertension; pulmonary endarterectomy; balloon pulmonary angioplasty; pharmacological treatment; pathophysiology

(This special issue belongs to the Section Respiratory Medicine)

Interventional Cardiology: Evolving Evidence and Emerging Horizons

edited by

Jacek Bil

submission deadline 31 Jul 2026 | Viewed by 39 | Submission Open

Keywords: coronary artery disease; percutaneous coronary intervention; drug-coated balloon; intravascular imaging; fractional flow reserve; transcatheter aortic valve implantation; transcatheter mitral valve repair; clinical outcomes

(This special issue belongs to the Section Cardiology)

Advances in Artificial Intelligence Applications for Invasive and Non-Invasive Cardiovascular Procedures

edited by

Oladipupo Olafiranye

and Rahul Chaudhary

submission deadline 31 Jul 2026 | Viewed by 39 | Submission Open

Keywords: artificial intelligence and machine learning; interventional cardiology; electrophysiology; cardiovascular imaging; remote patient monitoring; digital biomarkers; clinical decision support

(This special issue belongs to the Section Cardiovascular Medicine)

Blood Pressure Disorders: Risk Assessment, Surveillance and Clinical Interventions

edited by

Barbara Nikolaidou

submission deadline 7 Aug 2026 | Viewed by 26 | Submission Open

Keywords: hypertension; secondary hypertension; hypotension; target organ damage; hypertension phenotypes; hypertension emergency; hypertension urgency; microangiopathy; macroangiopathy; endothelial dysfunction; hypovolaemia; cardiogenic shock; dysautonomia

(This special issue belongs to the Section Cardiovascular Medicine)

Sports Cardiology: Current Clinical Status and Outlook into the Future

edited by Aakash Bavishi and Matthew W Martinez

submission deadline 10 Aug 2026 | Viewed by 89 | Submission Open

Keywords: sports cardiology; athletes; cardiac imaging; hypertrophic cardiomyopathy; screening; electrocardiogram; electrophysiology; echocardiography; sudden cardiac death

(This special issue belongs to the Section Cardiology)

New Insights into Glaucoma: 2nd Edition

edited by

Su-Ho Lim

and

Daniel Laroche

submission deadline 10 Aug 2026 | Viewed by 67 | Submission Open

Keywords: glaucoma; intraocular pressure (IOP); risk calculators; glaucoma screening glaucoma surgery; cataract surgery; trabeculectomy; glaucoma drainage devices; minimally invasive glaucoma surgery (MIGS); artificial intelligence (AI)

(This special issue belongs to the Section Ophthalmology)

Advances in Musculoskeletal Rehabilitation and Functional Movement

edited by Sanghee Park

submission deadline 13 Aug 2026 | Viewed by 39 | Submission Open

Keywords: corrective exercise; functional training; biomechanics; resistance training; movement impairment; electromyography; muscle activation; musculoskeletal rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Spine Surgery: Novel Challenges and Opportunities

edited by

Tae-Hwan Kim

submission deadline 15 Aug 2026 | Viewed by 80 | Submission Open

Keywords: spine surgery; surgical outcomes; postoperative care; complications; epidemiology; diagnostic imaging; biomaterials; biomechanics; machine learning; artificial intelligence; predictive modeling; minimally invasive techniques; population-based studies; clinical decision-making

(This special issue belongs to the Section Orthopedics)

Neurovascular Canvas: From Basic Science to Clinical Breakthroughs

edited by

Ciro De Luca

, Nicola Giannini and

Alessandro Viganò

submission deadline 15 Aug 2026 | Viewed by 68 | Submission Open

Keywords: neurovascular unit (NVU); neurodegeneration; vascular biology; stroke; disease modeling

(This special issue belongs to the Section Clinical Neurology)

Clinical Neuroscience Insights: Exploring the Advances in Brain Health

edited by

Simona Massimino

and Francesco Tomaiuolo

submission deadline 15 Aug 2026 | Viewed by 42 | Submission Open

Keywords: neurodegenerative diseases; cognitive impairment; neuromodulation therapy; brain health; cognitive and affective processes; neurorehabilitation

(This special issue belongs to the Section Clinical Neurology)

Gene Correction and Regenerative Therapies for Inherited Retinal Diseases: Clinical Perspectives

edited by Sushma Kalmodia

submission deadline 15 Aug 2026 | Viewed by 35 | Submission Open

Keywords: gene therapy; AAV; IRD; retinal organoids; RPE

(This special issue belongs to the Section Ophthalmology)

From Gastritis to Gastric Cancer: Challenges in Diagnosis and Long-term Management

edited by

Zuzanna Pelc

and

Karol Rawicz-Pruszyński

submission deadline 15 Aug 2026 | Viewed by 32 | Submission Open

Keywords: gastric cancer; gastritis and H. pylori; early detection and endoscopy; multimodal treatment; molecular profiling (MSI/MMR; PD-L1; CLDN18.2; HER2)

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

From Imaging to Intervention: Modern Approaches in Spine Disorders Management

edited by

Maria Chiara Maccarone

submission deadline 15 Aug 2026 | Viewed by 31 | Submission Open

Keywords: adolescent idiopathic scoliosis (AIS); spinal fusion; Cobb angle; bracing; skeletal maturity; radiographic imaging; multidisciplinary management

(This special issue belongs to the Section Orthopedics)

Advances in the Diagnosis, Treatment and Prognosis of Aortic Stenosis: 2nd Edition

edited by Rita Milewski

submission deadline 15 Aug 2026 | Viewed by 30 | Submission Open

Keywords: aortic valve stenosis; aortic valve replacement; surgical aortic valve replacement; transfemoral aortic valve replacement; risk stratification for aortic stenosis

(This special issue belongs to the Section Cardiology)

Redefining Hemodialysis: Beyond Diffusion to Precision Therapy

edited by

Stefano Stuard

and Sagar Nigwekar

submission deadline 15 Aug 2026 | Viewed by 29 | Submission Open

Keywords: digitalized medical governance; precision dialysis; convective clearance; advanced membranes; hemodynamic stability; artificial intelligence; digital biomarkers; personalized prescription; cardiovascular protection; patient-reported outcome measures; clinical trial emulation

(This special issue belongs to the Section Nephrology & Urology)

Hypertension and Cardiovascular Disease: Clinical Updates and Perspectives: 2nd Edition

edited by

Valeria Visco

submission deadline 15 Aug 2026 | Viewed by 29 | Submission Open

Keywords: hypertension management; cardiovascular risk assessment; novel antihypertensive therapies; hypertension in pregnancy; hypertensive emergencies; cardiovascular disease prevention; pharmacological interventions for cardiovascular disease

(This special issue belongs to the Section Cardiovascular Medicine)

Patient Safety and Clinical Outcomes in Robotic-Assisted Microsurgery and Endoscopic Surgery

edited by Tetsuji Uemura

submission deadline 15 Aug 2026 | Viewed by 14 | Submission Open

Keywords: endoscopic surgery; reconstructive surgery; robotic-assisted microsurgery; advanced surgical technologies; patient safety

(This special issue belongs to the Section General Surgery)

Advances in the Diagnosis and Management of Age-Related Macular Degeneration: 3rd Edition

edited by Tsutomu Yasukawa

submission deadline 20 Aug 2026 | Viewed by 237 | Submission Open

Keywords: age-related macular degeneration; angiography; anti-vascular endothelial growth factor therapy; geographic atrophy; macular neovascularization; multimodal imaging; ophthalmology; optical coherence tomography; photodynamic therapy; retinal pigment epithelium

(This special issue belongs to the Section Ophthalmology)

New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches

edited by Gabriella Teresa Capolupo

submission deadline 20 Aug 2026 | Viewed by 124 | Submission Open

Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

From Clinical Diagnosis to Effective Treatment of Cardiomyopathy

edited by

Sanjay Sivalokanathan

and

Łukasz A. Małek

submission deadline 20 Aug 2026 | Viewed by 104 | Submission Open

Keywords: hypertrophic cardiomyopathy; dilated cardiomyopathy; non-ischemic cardiomyopathy; cardiac MRI; PET/CT; PET/MRI; cardiac imaging; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Current Trends and Innovations in Coronary Artery Disease and Myocardial Ischemia: Second Edition

edited by

Edoardo Conte

submission deadline 20 Aug 2026 | Viewed by 78 | Submission Open

Keywords: coronary artery disease; fractional flow reserve; invasive coronary angiography; cardiac CT; cardiac MRI

(This special issue belongs to the Section Cardiovascular Medicine)

Sepsis and Septic Shock: Diagnosis, Treatment, and Prognosis

edited by Luigi Carbone and Daniela Pugliese

submission deadline 20 Aug 2026 | Viewed by 76 | Submission Open

Keywords: sepsis; septic shock; diagnosis and screening tools; risk stratification; machine learning; advanced therapies

(This special issue belongs to the Section Intensive Care)

Physical Therapy in Musculoskeletal Disorders: Prevention, Diagnosis, Clinical Management and Treatment—2nd Edition

edited by

Rubén Cuesta-Barriuso

submission deadline 20 Aug 2026 | Viewed by 72 | Submission Open

Keywords: physical therapy; musculoskeletal disorders; prevention; diagnosis; clinical management; treatment

(This special issue belongs to the Section Clinical Rehabilitation)

Anterior Segment Disorders

edited by Itay Lavy and

Nir Erdinest

submission deadline 20 Aug 2026 | Viewed by 62 | Submission Open

Keywords: anterior segment disorders; corneal disease; cataract surgery; ocular surface disease; surgical outcomes; surgical techniques; artificial intelligence in diagnosis; diagnostic imaging; pharmacological and surgical interventions; refractive errors; anterior uveitis; keratitis; corneal ectasia; quality of life

(This special issue belongs to the Section Ophthalmology)

Retinal Diseases: Recent Advances in Diagnosis and Treatment—2nd Edition

edited by Dario Giorgio and Dario Pasquale Mucciolo

submission deadline 20 Aug 2026 | Viewed by 59 | Submission Open

Keywords: retinal diseases; retinal degeneration; macular degeneration; OCT; retinal imaging

(This special issue belongs to the Section Ophthalmology)

Advances in the Management of Cervical Spine Trauma

edited by

Jong-Beom Park

and

Sung-kyu Kim

submission deadline 20 Aug 2026 | Viewed by 58 | Submission Open

Keywords: cervical spine trauma; cervical fracture; high cervical injury; subaxial injury; surgical management; occipitocervical fusion; C1 fracture; C2 fracture; spinal stability; trauma imaging; spinal cord injury; neurological outcome

(This special issue belongs to the Section Orthopedics)

Clinical Updates on Reproductive Endocrinology in Children and Adolescents

edited by

Charikleia Stefanaki

submission deadline 20 Aug 2026 | Viewed by 53 | Submission Open

Keywords: reproductive endocrinology; adolescents; male hypogonadism; female hypogonadism; reproductive metabolism; PCOS; POF; receptor abnormalities; menstrual cycle; transgender health; CAH; ovaries; gonads; hormones; sex development; amenorrhea; estrogen resistance; androgen resistance; teen pregnancy; oncology; preservation of fertility

(This special issue belongs to the Section Clinical Pediatrics)

Displaying special issue 1401-1450 on page 29 of 31.

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