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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Updates on Pediatric Neurological Disorders and Neurorehabilitation submission deadline 20 Mar 2027 | 2 articles | Viewed by 2157 | Submission Open
Keywords: child neurological disorders; neurorehabilitation; neurogenetics; treatment; quality of life; rehabilitation teams; congenital brain disorders; trauma; movement disorders; cerebral palsy
(This special issue belongs to the Section Clinical Pediatrics)
Rehabilitation in Musculoskeletal Disease
edited by
submission deadline 20 Mar 2027 | 3 articles | Viewed by 2134 | Submission Open
Keywords: musculoskeletal disease; stroke rehabilitation; physical therapy; rehabilitation; chronic pain; manual therapy; exercise intervention
(This special issue belongs to the Section Clinical Rehabilitation)
Clinical Advances in Lower Limb Trauma and Orthopedic Surgery: From Bench to Bedside
edited by and
submission deadline 20 Mar 2027 | 3 articles | Viewed by 2097 | Submission Open
Keywords: lower limb trauma; fracture fixation; arthroplasty; biomechanics; orthopaedic surgery; clin-ical outcomes; minimally invasive techniques; rehabilitation
(This special issue belongs to the Section Orthopedics)
Novel Perspectives in Transcatheter Aortic Valve Implantation
edited by Nay Min Htun
submission deadline 20 Mar 2027 | 2 articles | Viewed by 2071 | Submission Open
Keywords: TAVI; life-time management; TAVI-in-TAVI; bicuspid valve; pure aortic regurgitation; small annuli
(This special issue belongs to the Section Cardiology)
New Insights into Cardiovascular Radiology
edited by Amalia Lupi and
submission deadline 20 Mar 2027 | 3 articles | Viewed by 2048 | Submission Open
Keywords: CMR; tissue characterization; 4Dflow; CCTA; photon counting CT; plaque characterization
(This special issue belongs to the Section Nuclear Medicine & Radiology)
New Perspective of Oral and Maxillo-Facial Surgery: 2nd Edition
edited by , and Alessandra Lucchese
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1939 | Submission Open
Keywords: maxillofacial surgery; esthetic surgery; orthognatic surgery; TMJ disorders; TMJ surgery; dental implant surgery; 3D imaging; printing applications; tissue engineering; personalized treatment planning; artificial intelligence; squamous cell carcinoma; skin tumors; plastic and reconstructive surgery; head and neck surgery; ENT surgery
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Optimizing the Surgical Journey: From Abdominal Operation to Recovery
edited by and Carlo Bergamini
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1927 | Submission Open
Keywords: surgical complications; comanagement; comorbidities; elective surgical procedure; emergency surgery procedure; multidisciplinary approach; hospitalist
(This special issue belongs to the Section General Surgery)
Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Advancing Diagnosis and Management
edited by Olga Reitblat
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1906 | Submission Open
Keywords: cataract surgery; premium intraocular lenses (IOLs); IOL power calculation; visual outcomes; refractive cataract surgery; multifocal IOL; extended depth of focus (EDOF) IOL; toric IOL; full range; vision IOL; biometry
(This special issue belongs to the Section Ophthalmology)
Minimally Invasive Spine Surgery: Evidence, Advances and Controversies
edited by , Constantine Constantoyannis, and Oliver Lasry
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1902 | Submission Open
Keywords: spine surgery; minimally invasive; MIS; MISS; endoscopic; tubular; fusion; laminectomy; discectomy; decompression; percutaneous; robotic; robotic-assisted; navigation; augmented-reality
(This special issue belongs to the Section Clinical Neurology)
Recent Advances in Vitreoretinal Surgery: 2nd Edition
edited by
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1851 | Submission Open
Keywords: vitrectomy; retinal detachment; macular holes; pediatric vitreoretinal surgery; vitrectomy instrumentation; macular surgery; complex retinal detachments; vitreoretinal surgery
(This special issue belongs to the Section Ophthalmology)
The Diagnosis and Treatment of Endometriosis
edited by
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1847 | Submission Open
Keywords: endometriosis; infertility; pregnancy; hysterosalpingography; deep lesions; medical imaging; diagnostic techniques; ultrasonography; magnetic resonance imaging (MRI); laparoscopy; pelvic imaging; fertility assessment; imaging modalities; gynecological imaging; radiological approaches; reproductive medicine; immunotherapy; inflammation; antioxidants
(This special issue belongs to the Section Obstetrics & Gynecology)
Clinical Challenges and Future Directions of Interstitial Lung Disease
edited by
submission deadline 20 Mar 2027 | 4 articles | Viewed by 1817 | Submission Open
Keywords: interstitial lung disease; progressive pulmonary fibrosis; early detection; clinical diagnosis; multidisciplinary discussion; treatment; non-pharmacological therapy; end-of-life care; patient-centered management
(This special issue belongs to the Section Respiratory Medicine)
Gynecologic Cancers: Current Clinical Management and Multidisciplinary Treatment Strategies submission deadline 20 Mar 2027 | 1 articles | Viewed by 1810 | Submission Open
Keywords: gynecologic; cancer; uterus; ovarian; endometrial; cervical
(This special issue belongs to the Section Obstetrics & Gynecology)
Advances in Interventional Cardiology: From Access to Outcomes
edited by James Cotton and Benjamin Wrigley
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1730 | Submission Open
Keywords: interventional cardiology; acute coronary syndrome; chronic coronary syndrome; TAVI; TAVR; TEER; TMVR; T-TEER; TTVR; service redesign
(This special issue belongs to the Section Cardiology)
Orthodontics: Current Management and Future Options
edited by Arūnas Vasiliauskas and Aistė Kavaliauskienė
submission deadline 20 Mar 2027 | 3 articles | Viewed by 1718 | Submission Open
Keywords: digital orthodontics; clear aligner therapy; accelerated tooth movement; micro-implants; artificial intelligence; patient-centred outcomes; treatment efficiency
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Novel Research in Cardiovascular Imaging
edited by Stanciu Silviu and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1699 | Submission Open
Keywords: echocardiography; cardiac CT; CMR; nuclear medicine; artificial intelligence
(This special issue belongs to the Section Cardiovascular Medicine)
Management of Diabetes-Related Cardiovascular Disease: Current Treatment and Future Options
edited by Antonio J. Amor and Tonet Serés-Noriega
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1683 | Submission Open
Keywords: type 1 diabetes; type 2 diabetes; cardiovascular disease; biomarkers; atherosclerosis; cardioprotective drugs; vascular ultrasound
(This special issue belongs to the Section Cardiovascular Medicine)
Clinical Outcomes in Lumbar Spinal Stenosis Treatment
edited by Rafał Staszkiewicz and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1647 | Submission Open
Keywords: lumbar spinal stenosis; clinical outcomes; decompression surgery; conservative management; molecular biomarkers; inflammation and fibrosis; neurotrophic factors; personalized medicine; siganling pathways; quality of life
(This special issue belongs to the Section Orthopedics)
Maxillofacial Surgery in the Modern Era: Surgical Advances and Clinical Innovation submission deadline 20 Mar 2027 | 1 articles | Viewed by 1639 | Submission Open
Keywords: maxillofacial surgery; oral surgery; craniofacial surgery; plastic surgery; bone
(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)
Diabetic Foot: From Prevention to Diagnosis and Treatment
edited by , and Michael Edmonds
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1526 | Submission Open
Keywords: diabetic foot ulcer; peripheral arterial disease; diabetic foot infection; Charcot foot; diabetic foot mortality
(This special issue belongs to the Section Endocrinology & Metabolism)
Current Therapeutic Approaches to Addictive Disorders
edited by Linda Haddad
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1431 | Submission Open
Keywords: addiction treatment; dependence; withdrawal management; relapse prevention; recovery; rehabilitation and support
(This special issue belongs to the Section Mental Health)
Diagnosis and Treatment of Pleura and Lung: Clinical Advances in Intensive Care submission deadline 20 Mar 2027 | 1 articles | Viewed by 1255 | Submission Open
Keywords: thoracic drainage; lung recruitment; lung ultrasound; pleural effusion; pneumothrax; B-line; lung atelectasis
(This special issue belongs to the Section Intensive Care)
New Insights in Trauma and Emergency Surgery
edited by Kai Oliver Jensen and Valentin Neuhaus
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1243 | Submission Open
Keywords: trauma and emergency surgery; multiple trauma; orthopedic trauma; surgery; concepts in trauma
(This special issue belongs to the Section Emergency Medicine)
Rebuilding the Knee: From Repair to Replacement and Recovery
edited by Young-Jin Seo
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1223 | Submission Open
Keywords: cartilage; meniscus; total knee arthroplasty; knee surgery; anterior cruciate ligament injuries; posterior cruciate ligament injuries; ligament reconstruction; patellofemoral disorders; osteotomy; sports medicine; rehabilitation; functional recovery
(This special issue belongs to the Section Orthopedics)
Digital Innovations in Obstetrics and Gynecology: Artificial Intelligence, Diagnostic Advances, Minimally Invasive Surgery, and Clinical Decision-Making
edited by
submission deadline 20 Mar 2027 | 2 articles | Viewed by 1193 | Submission Open
Keywords: obstetrics; gynecology; artificial intelligence; machine learning; minimally invasive surgery; digital health
(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Clinical Medicine)
Pulmonary Hypertension and Chronic Lung Disease: Diagnosis and Management submission deadline 20 Mar 2027 | 1 articles | Viewed by 1180 | Submission Open
Keywords: pulmonary hypertension; chronic obstructive pulmonary disease (COPD); chronic lung disease; epidemiology; exacerbations; comorbidities; risk factors; diabetes; systemic inflammation; real-world data
(This special issue belongs to the Section Respiratory Medicine)
Exploring Diagnostic and Therapeutic Advances in Neurodegenerative Disorders submission deadline 20 Mar 2027 | 1 articles | Viewed by 1129 | Submission Open
Keywords: neurodegenerative disease; Parkinson’s disease; Alzheimer’s disease; Friedreich’s ataxia; Huntington’s disease; Lewy body dementia; dementia; immunosenescence; inflammaging
(This special issue belongs to the Section Clinical Neurology)
Colorectal Surgery: Advances in Modern Clinical Management submission deadline 20 Mar 2027 | 2 articles | Viewed by 1082 | Submission Open
Keywords: colorectal cancer management; surgery; complications; organ preservation; screening; colonic diverticular disease; colonic diverticulitis; hemorrhoids
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Updates on Reconstructive Urology
edited by
submission deadline 20 Mar 2027 | 1 articles | Viewed by 1065 | Submission Open
Keywords: reconstructive urology; urethral stenosis; urethroplasty; urethral diverticulum; ureteral stenosis; male incontinence; urinary diversion; hypospadias; microsurgery; experimental microsurgery; bladder diverticulum; neobladder
(This special issue belongs to the Section Nephrology & Urology)
Thyroid Cancer: Diagnosis, Surgical Treatment and Postoperative Radioactive Iodine Therapy: 2nd Edition
edited by Alfred A. Simental
submission deadline 20 Mar 2027 | 2 articles | Viewed by 996 | Submission Open
Keywords: thyroid nodule; thyroid ultrasound; radiofrequency ablation; molecular analysis; thyroid surgery
(This special issue belongs to the Section Oncology)
What We See Through Cardiac Imaging: Second Edition submission deadline 20 Mar 2027 | 1 articles | Viewed by 960 | Submission Open
Keywords: cardiomyopathies; multimodality imaging; echocardiography; cardiac-computed tomography; cardiac magnetic resonance; prognosis; arrhythmias; heart failure
(This special issue belongs to the Section Cardiology)
Hemophilia: Current Trends and Future Directions: 2nd Edition submission deadline 20 Mar 2027 | 1 articles | Viewed by 956 | Submission Open
Keywords: hemophilia; prophylaxis; gene therapy; burden of illness; quality of life; patient reported outcomes; hemarthrosis; women and hemophilia
(This special issue belongs to the Section Hematology)
Obsessive–Compulsive Disorder (OCD): Understanding, Treatment, and New Directions in Psychotherapy
edited by Franziska Sophia Miegel
submission deadline 20 Mar 2027 | 1 articles | Viewed by 897 | Submission Open
Keywords: obsessive–compulsive disorder; clinical psychopathology; mechanisms of change; psychotherapeutic interventions; treatment delivery; accessibility of care; innovative treatment approaches; technology-supported interventions
(This special issue belongs to the Section Mental Health)
Pediatric Orthopedics: Diagnosis, Treatment, and Comprehensive Management
edited by Michał Latalski and
submission deadline 20 Mar 2027 | 2 articles | Viewed by 851 | Submission Open
Keywords: pediatric orthopedics; cerebral palsy; SMA; spinal deformities; developmental dysplasia of the hip; clubfoot; neuro-orthopedics; gait analysis; pediatric traumatology; skeletal dysplasia; biomechanics; congenital musculoskeletal anomalies
(This special issue belongs to the Section Orthopedics)
Atrial Fibrillation: Contemporary Evidence from Prevention to Catheter Ablation
edited by , Radu Gabriel Vătăşescu and
submission deadline 20 Mar 2027 | 1 articles | Viewed by 807 | Submission Open
Keywords: atrial fibrillation; prevention; risk-factor modification; screening; rhythm control; catheter ablation; stroke prevention; outcomes
(This special issue belongs to the Section Cardiology)
Clinical Advances in Extracorporeal Membrane Oxygenation (ECMO)—Second Edition
edited by and
submission deadline 20 Mar 2027 | 1 articles | Viewed by 801 | Submission Open
Keywords: extracorporeal membrane oxygenation; ECMO; multi-organ failure; outcomes; V-A ECMO; ECPR; V-V ECMO; translational research; clinical research
(This special issue belongs to the Section Intensive Care)
New Perspectives in the Diagnosis and Management of Skin Cancer
edited by Emily Avitan-Hersh
submission deadline 20 Mar 2027 | 1 articles | Viewed by 744 | Submission Open
Keywords: skin cancer; melanoma; cutaneous lymphoma; Kaposi; Merkel cell carcinoma; basal cell carcinoma; immunotherapy
(This special issue belongs to the Section Dermatology)
Contactless Magnetocardiography and Related Novel Methods for Non-Invasive Experimental and Clinical Functional Imaging of Normal and Abnormal Cardiac Electrophysiology submission deadline 20 Mar 2027 | 1 articles | Viewed by 650 | Submission Open
Keywords: magnetocardiography; non-invasive functional imaging of cardiac electrophysiology; arrhythmogenic mechanisms; atrial fibrillation; magnetoionography; antiarrhythmic drugs; artificial intelligence
(This special issue belongs to the Section Cardiology)
New Clinical Insight: From Open Surgery to Minimally Invasive Foot and Ankle Surgery
edited by Enrique A. Testa and Daniel Poggio
submission deadline 20 Mar 2027 | 1 articles | Viewed by 587 | Submission Open
Keywords: minimally invasive surgery; foot surgery; ankle surgery; trauma surgery; orthopedic surgery; ankle arthroscopy
(This special issue belongs to the Section Orthopedics)
New Insights into Gastrointestinal Surgery: Advances in Techniques and Treatment Approaches
edited by Gabriella Teresa Capolupo
submission deadline 20 Mar 2027 | Viewed by 538 | Submission Open
Keywords: gastroenterology; gastrointestinal surgery; colorectal surgery; robotic surgery; technologies; minimally invasive surgery
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Current Challenges and Innovation in Trauma and Acute Care Surgery
edited by Michel Teuben
submission deadline 20 Mar 2027 | Viewed by 510 | Submission Open
Keywords: traumatology; trauma surgery; acute care surgery; femur; injury
(This special issue belongs to the Section Emergency Medicine)
Advances in Neuro-Oncology: Diagnostics and Treatment
edited by and Derek A. Wainwright
submission deadline 20 Mar 2027 | 1 articles | Viewed by 468 | Submission Open
Keywords: glioblastoma; glioma; meningioma; brain metastases; blood–brain barrier
(This special issue belongs to the Section Clinical Neurology)
Gastrointestinal Surgery: New Insights into Tumor Metabolism and Translational Oncology
edited by Konstantinos Romanidis
submission deadline 20 Mar 2027 | 1 articles | Viewed by 449 | Submission Open
Keywords: gastrointestinal cancer; tumor metabolism; translational oncology; surgical oncology; metabolic profiling; artificial intelligence
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Recent Advances in the Surgical Treatment of Heart Valve Disease
edited by and Aleksander Dokollari
submission deadline 20 Mar 2027 | Viewed by 408 | Submission Open
Keywords: heart valve surgery; prosthetic valves; intervention surgery; minimally invasive and robotic surgery; valve repair and replacement
(This special issue belongs to the Section Cardiology)
Clinical Updates on Anesthesia and Perioperative Medicine
edited by Béla Fülesdi and
submission deadline 20 Mar 2027 | Viewed by 408 | Submission Open
Keywords: anesthesia; perioperative complications; residual neuromuscular block; postoperative pulmonary complications; intensive care unit acquired weakness; intensive care medicine; airway management; patient safety
(This special issue belongs to the Section Anesthesiology)
Acute Cardiovascular Care in Cardio-Oncology: Present Challenges and Future Pathways
edited by and Maria Bergami
submission deadline 20 Mar 2027 | Viewed by 390 | Submission Open
Keywords: cardiotoxicity; cardio-oncology; acute cardiovascular care; acute cardiovascular complications; disparities in care
(This special issue belongs to the Section Cardiovascular Medicine)
Neuroimmunology in Neurological Disorders: Clinical Diagnosis and Treatment
edited by Charalampos Skarlis, and
submission deadline 20 Mar 2027 | Viewed by 383 | Submission Open
Keywords: neuroimmunology; neuroinflammation; neurodegenerative diseases; Parkinson’s disease; multiple sclerosis; CNS autoimmune disease; biomarkers; immunomodulatory therapy
(This special issue belongs to the Section Clinical Neurology)
Gastroparesis: Emerging Insights and Endoscopic Therapeutic Strategies
edited by Sabrina Testoni
submission deadline 20 Mar 2027 | Viewed by 381 | Submission Open
Keywords: gastroparesis; gastric dismotility; gastric emptying; gastric per-oral miotomy; pyloromyotomy; gastric electric stim-ulation; botulinum toxin
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Clinical Advances in Pediatric Hepatobiliary Surgery
edited by Ioannis A. Ziogas
submission deadline 20 Mar 2027 | Viewed by 380 | Submission Open
Keywords: pediatric hepatobiliary surgery; pediatric transplantation; pediatric surgery; liver transplantation; biliary atresia; choledochal cyst; liver cancer
(This special issue belongs to the Section Clinical Pediatrics)
Clinical Updates on Application of Echocardiography
edited by Aydan Ewers
submission deadline 20 Mar 2027 | Viewed by 369 | Submission Open
Keywords: echocardiography; heart failure; cardiomyopathies; cardiac echocardiography; interventional cardiology; cardiac imaging; pulmonary hypertension
(This special issue belongs to the Section Cardiology)
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