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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Aortic Surgery: State of the Art and Future Directions

edited by

Dimos E. Karangelis

submission deadline 15 Jun 2026 | Viewed by 40 | Submission Open

Keywords: aortic surgery; aortic aneurysm; aortic dissection; aortic arch; biomaterials; endovascular approach; FET; TEVAR

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Diagnosis and Management of Erectile Dysfunction

edited by Maurizio De Rocco Ponce and

Giuseppe Grande

submission deadline 15 Jun 2026 | Viewed by 36 | Submission Open

Keywords: erectile dysfunction; clinical management; cardiovascular disease; penile prosthesis; personalized medicine; hipogonadism

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Novel Diagnostic and Therapeutic Perspectives in Systemic Sclerosis

edited by Mislav Radić

submission deadline 15 Jun 2026 | Viewed by 33 | Submission Open

Keywords: systemic sclerosis; biomarkers; diagnosis; treatment; diagnostic imaging technique; early detection

(This special issue belongs to the Section Immunology & Rheumatology)

Gynecologic Oncology: Current Therapies and New Frontiers

edited by Laura Paleari and Mariangela Rutigliani

submission deadline 19 Jun 2026 | Viewed by 62 | Submission Open

Keywords: ovarian cancers; gynecological cancer; drug delivery; AI; screening; new therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Gynecologic and Obstetric Pathologies: From Birth to Menopause (Third Edition)

edited by

Panagiotis Christopoulos

submission deadline 20 Jun 2026 | 6 articles | Viewed by 19285 | Submission Open

Keywords: obstetrics; gynecology; pathology; pediatric and adolescent gynecology; menopause; urinary disorders; infertility; gynecologic oncology; maternal– fetal medicine; incontinence; menstruation; reproduction; polycystic ovarian syndrome; endometriosis; dysmenorrhea; assisted reproduction; IVF; laparoscopy; hysteroscopy; gynecologic robotic surgery; high-risk pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Advances in Trauma Care and Emergency Medicine

edited by

Lothar Andreas Schwarte

Patrick Schober

and

Georgios F. Giannakopoulos

submission deadline 20 Jun 2026 | 2 articles | Viewed by 12939 | Submission Open

Keywords: trauma; trauma care; emergency medicine; pre-hospital; emergency room; intensive care unit

(This special issue belongs to the Section Emergency Medicine)

Clinical Advances in Metabolic Dysfunction-Associated Steatotic Liver Disease

edited by Hirsh D. Trivedi

submission deadline 20 Jun 2026 | 5 articles | Viewed by 9244 | Submission Open

Keywords: metabolic dysfunction-associated steatotic liver disease; MASLD; non-alcoholic fatty liver disease; NAFLD; liver disease; liver fibrosis; metabolic syndrome

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Latest Advances in Orthodontics

edited by

Giuseppina Laganà

submission deadline 20 Jun 2026 | 3 articles | Viewed by 6597 | Submission Open

Keywords: digital treatment planning; clear aligners; skeletal anchorage; OSAS; artificial intelligence

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advancements in Gait Rehabilitation: Innovative Approaches and Clinical Insights

edited by

Shinichi Watanabe

Nobuto Nakanishi

and

Yuki Iida

submission deadline 20 Jun 2026 | 4 articles | Viewed by 5582 | Submission Open

Keywords: sarcopenia; swallowing therapy; physical therapy; early mobilization; early rehabilitation; robot-assisted gait training; neurorehabilitation; wearable sensors

(This special issue belongs to the Section Clinical Rehabilitation)

Evidence-Based Diagnosis and Clinical Management of Low Back Pain

edited by

William J. Hanney

and

Michael Masaracchio

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4982 | Submission Open

Keywords: low back pain; classification systems; risk stratification; health services research; management strategies; timing and sequencing; prognosis; predictor; clinical decision making; primary care

(This special issue belongs to the Section Clinical Rehabilitation)

AI in Maternal Fetal Medicine and Perinatal Management

edited by Ariel Many

submission deadline 20 Jun 2026 | 2 articles | Viewed by 4839 | Submission Open

Keywords: maternal fetal medicine; high-risk pregnancy; perinatal management; artificial intelligence (AI) in obstetrics; fetal growth abnormalities; preterm labor prediction

(This special issue belongs to the Section Obstetrics & Gynecology)

Maternal–Fetal Medicine: Current Status, Challenges, and Future Directions

edited by Jessian Munoz

submission deadline 20 Jun 2026 | 3 articles | Viewed by 4175 | Submission Open

Keywords: maternal– fetal medicine; preterm delivery; preterm birth management; newborn; obstetrics; high-risk pregnancy; perinatal outcome; placenta accreta; fetal surgery

(This special issue belongs to the Section Obstetrics & Gynecology)

Advancements in Femtosecond Laser Applications

edited by Luca Schwarzenbacher, Eva Stifter and Philipp Roberts

submission deadline 20 Jun 2026 | 4 articles | Viewed by 4117 | Submission Open

Keywords: femtosecond laser; cataract surgery; DSAEK; DALK; femto-CAIRS; congenital cataract

(This special issue belongs to the Section Ophthalmology)

Ultrasound-Guided Biopsy of Gynecologic Tumors: Technique and Clinical Application

edited by

Athina A. Samara

and Alexandros Daponte

submission deadline 20 Jun 2026 | 1 articles | Viewed by 3229 | Submission Open

Keywords: ultrasound-guided biopsy; gynecologic tumors; ovarian cancer; biopsy technique; precision diagnosis; endometrial lesions

(This special issue belongs to the Section Obstetrics & Gynecology)

Antithrombotic Therapies for Acute Coronary Syndrome and Atrial Fibrillation

edited by

Mojca Božič Mijovski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2999 | Submission Open

Keywords: atrial fibrillation; acute coronary syndrome; antiplatelet agents; anticoagulants; thrombolysis; direct coagulation factor inhibitors; medical laboratory technology

(This special issue belongs to the Section Cardiology)

Genitourinary Cancers: Clinical Advances and Practice Updates

edited by David Benjamin and Arash Rezazadeh Kalebasty

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2695 | Submission Open

Keywords: rare tumors; genitourinary cancers; urachal cancer; penile cancer; testicular cancer; variant histology

(This special issue belongs to the Section Nephrology & Urology)

State-of-the-Art in Cardiac Surgery: Progress, Challenges and Opportunities

edited by Tomasz Plonek and Sleiman Sebastian Aboul-Hassan

submission deadline 20 Jun 2026 | 3 articles | Viewed by 2249 | Submission Open

Keywords: aorta ascendens; minimally invasive surgery; aortic arch surgery; off pump coronary surgery; arterial grafts

(This special issue belongs to the Section Cardiology)

Novel Aspects of Endocrine Care: From Patient-Centred Management of Endocrine Diseases to Guidelines Standards

edited by

Mara Carsote

and

Claudiu Nistor

submission deadline 20 Jun 2026 | 2 articles | Viewed by 2234 | Submission Open

Keywords: endocrine tumour; hormone; biomarker; neuroendocrine tumour; thyroidectomy; parathyroidectomy; bone; ad-renal gland; osteoporosis; pituitary gland; autoimmune; antibody; clinical study; computed tomography

(This special issue belongs to the Section Endocrinology & Metabolism)

New Insights in Maxillofacial Surgery

edited by

Izumi Asahina

submission deadline 20 Jun 2026 | 1 articles | Viewed by 2024 | Submission Open

Keywords: maxillofacial surgery; surgical techniques; imaging technologies; biomaterials; regenerative medicine

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Recent Advances in Transcatheter Aortic Valve Replacement: Second Edition

edited by

Anna Olasińska-Wiśniewska

and Maciej Dąbrowski

submission deadline 20 Jun 2026 | 2 articles | Viewed by 1790 | Submission Open

Keywords: aortic stenosis; transcatheter; bioprosthesis; TAVI; transcatheter aortic valve replacement

(This special issue belongs to the Section Cardiovascular Medicine)

Current Challenges and Perspectives in Liver Transplantation

edited by Bogdan Dorobanţu,

Umberto Cillo

and Waldo Concepcion

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1392 | Submission Open

Keywords: liver transplantation; liver surgery; liver cirrhosis; liver disease; alcoholic and non-alcoholic steatohepatitis; cholangiocarcinoma; hepatocellular carcinoma; auxiliary liver transplantation

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Current Perspectives and Innovations in Urogynecology

edited by Stavros Athanasiou

submission deadline 20 Jun 2026 | 1 articles | Viewed by 1017 | Submission Open

Keywords: urogynecology; pelvic organ prolapse; urinary incontinence; overactive bladder; pelvic floor surgery; reconstructive surgery; minimally invasive surgery; pelvic floor disorders; innovative surgical techniques; quality of life

(This special issue belongs to the Section Obstetrics & Gynecology)

Cardiovascular Imaging: Diagnosis and Therapeutic Guidance in Clinical Practice

edited by

Stefano Figliozzi

submission deadline 20 Jun 2026 | 1 articles | Viewed by 894 | Submission Open

Keywords: cardiovascular magnetic resonance; cardiac imaging; T1 and T2 mapping; myocardial tissue characterization; late gadolinium enhancement; ischemic heart disease; cardiomyopathies; valvular heart disease; therapeutic guidance; precision medicine; mitral valve prolapse

(This special issue belongs to the Section Cardiology)

Therapies for Heart Failure: Clinical Updates and Perspectives

edited by Cristina Tudoran, Stela Iurciuc and Dragos Cozma

submission deadline 20 Jun 2026 | 1 articles | Viewed by 672 | Submission Open

Keywords: mechanisms of heart failure; new therapies for heart failure; chronic and acute heart failure; new approaches to managing heart failure patients; special populations; clinical outcome

(This special issue belongs to the Section Cardiology)

Clinical Advances in the Pharmacotherapy of Diabetes

edited by Jonathan Watanabe,

Joshua J. Neumiller

and

Cheyenne Frazier

submission deadline 20 Jun 2026 | 1 articles | Viewed by 596 | Submission Open

Keywords: diabetes; microvascular complications; macrovascular complications; diabetes technology; pharmacoepidemiology; care delivery; novel therapies

(This special issue belongs to the Section Pharmacology)

The New Era of Urological Surgery: Technology-Enhanced Clinical Outcomes

edited by

Razvan-George Rahota

and

Guillaume Ploussard

submission deadline 20 Jun 2026 | Viewed by 555 | Submission Open

Keywords: urology; surgery; robotic surgery; artificial intelligence; urological cancer

(This special issue belongs to the Section Nephrology & Urology)

Stroke in Patients with Atrial Fibrillation: Risk, Manifestation and Prevention

edited by

Iwona Gorczyca-Głowacka

submission deadline 20 Jun 2026 | 1 articles | Viewed by 476 | Submission Open

Keywords: anticoagulant treatment; atrial fibrillation; arrhythmia; personalized medicine; stroke

(This special issue belongs to the Section Cardiology)

Novel Insights into the Use of Artificial Intelligence in Clinical Medicine

edited by Sharon C. Kiang and Roger T. Tomihama

submission deadline 20 Jun 2026 | 1 articles | Viewed by 434 | Submission Open

Keywords: artificial intelligence; disease predictive models; wearable technology; surgical innovation; molecular targeting; big data science; machine learning; deep learning

Orthopedic Oncology Updates and Controversial Issues

edited by Yehuda Kollender and Ron Batash

submission deadline 20 Jun 2026 | Viewed by 395 | Submission Open

Keywords: soft tissue sarcoma; bone sarcoma; oligometastatic; atypical behavior tumor; cryosurgery; rare diseases; surgery; radiation therapy; immunotherapy; chemotherapy

(This special issue belongs to the Section Orthopedics)

Neuroimmunological Disorders: Mechanisms and Therapies

edited by

Christos Bakirtzis

and

Marina Kleopatra Boziki

submission deadline 20 Jun 2026 | 1 articles | Viewed by 373 | Submission Open

Keywords: neuroinflammatory; multiple sclerosis; neuromyelitis optica spectrum disorders; mog associated disease; autoimmune/paraneoplastic encephalitis

(This special issue belongs to the Section Clinical Neurology)

Parkinson's Disease: Recent Advances in Diagnosis and Treatment

edited by

Mariachiara Sensi

and

Fabiana Colucci

submission deadline 20 Jun 2026 | Viewed by 362 | Submission Open

Keywords: Parkinson’ s disease; disease-modifying therapies; artificial intelligence; microbiome; alpha-synuclein; neuroimaging

(This special issue belongs to the Section Clinical Neurology)

Advanced Endoscopy and Imaging in Gastrointestinal Diseases

edited by

Iancu Dana Monica

and

Paul-Andrei Ștefan

submission deadline 20 Jun 2026 | 1 articles | Viewed by 334 | Submission Open

Keywords: advanced endoscopy; gastrointestinal imaging; minimally invasive therapy; early diagnosis; image-guided intervention; surgical planning; patient outcomes; gastrointestinal diseases

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Advances in Oral and Facial Surgery: 2nd Edition

edited by

Olindo Massarelli

submission deadline 20 Jun 2026 | 1 articles | Viewed by 328 | Submission Open

Keywords: squamous cell carcinoma; oro-pharyngeal tumors; skin tumors; plastic and reconstructive surgery; facial plastic surgery; facial reanimation; facial nerve palsy; head and neck surgery; maxillofacial surgery; aesthetic surgery; orthognatic surgery; dental implant surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances and Challenges in Liver Transplantation: 3rd Edition

edited by

Paola Aceto

submission deadline 20 Jun 2026 | 1 articles | Viewed by 234 | Submission Open

Keywords: liver transplantation (LT); elderly donors; steatotic livers; donors after circulatory death (DCD); hepatocellular carcinoma (HCC); perioperative management

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Pulmonary Critical Care: Integrating Bedside Physiology and Advanced Monitoring in the Management of Severe Respiratory Diseases

edited by

Gaetano Scaramuzzo

submission deadline 20 Jun 2026 | Viewed by 215 | Submission Open

Keywords: lung monitoring; ARDS; ARF; biomarkers; lung physiology; pneumonia; lung ultrasound; artificial intelligence; COPD; EIT

(This special issue belongs to the Section Respiratory Medicine)

Advances in Cardiovascular Rehabilitation: The Central Role of Exercise in Prevention and Care

edited by Massimo Pistono

submission deadline 20 Jun 2026 | 1 articles | Viewed by 191 | Submission Open

Keywords: cardiac rehabilitation; secondary prevention; physical exercise; cardiovascular health; aerobic exercise; cardio-oncology rehabilitation

(This special issue belongs to the Section Cardiovascular Medicine)

The Treatment of BPO with Minimal Invasive Approach

edited by

Lukas Lusuardi

submission deadline 20 Jun 2026 | Viewed by 159 | Submission Open

Keywords: benign prostatic obstruction (BPO); prostatectomy; non-muscle invasive bladder cancer; muscle invasive bladder cancer; robotic surgery

(This special issue belongs to the Section Nephrology & Urology)

Physiotherapy and Therapeutic Exercise in Modern Clinical Practice

edited by Andoni Carrasco Uribarren,

Luis Ceballos-Laita

and

Carolina Climent-Sanz

submission deadline 20 Jun 2026 | Viewed by 126 | Submission Open

Keywords: exercise therapy; physiotherapy; therapeutic exercise; musculoskeletal disorders; musculoskeletal rehabilitation; pain management; patient-centered care; physiotherapy; rehabilitation technology

(This special issue belongs to the Section Orthopedics)

Oral and Maxillofacial Surgery: Clinical Progress, Challenges and Opportunities

edited by Janet Hayes Southerland and Leslie Robin Halpern

submission deadline 20 Jun 2026 | Viewed by 126 | Submission Open

Keywords: OMFS; surgery; research; innovation; interdisciplinary; cosmetic; pharmacology; cancer; repair; nerve; TMJ; rehabilitation; orthognathic; disorder; bleeding

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Advances in Scoliosis and Spinal Disorders: Diagnosis and Management

edited by Tejas Subramanian

submission deadline 20 Jun 2026 | 1 articles | Viewed by 120 | Submission Open

Keywords: spine surgery; adult spinal deformity; frailty; sarcopenia; muscle health; postoperative recovery; patient-reported outcomes

(This special issue belongs to the Section Orthopedics)

Sepsis: Clinical Advances and Practical Updates

edited by

Paolo Formenti

submission deadline 20 Jun 2026 | Viewed by 114 | Submission Open

Keywords: sepsis pathophysiology; host immune response; biomarkers for sepsis; early sepsis diagnosis; immunotherapy in sepsis; antimicrobial stewardship

(This special issue belongs to the Section Intensive Care)

Pediatric Ophthalmology: Current Progress and Future Options

edited by

Claudia Yahalom

and

Nir Erdinest

submission deadline 20 Jun 2026 | Viewed by 91 | Submission Open

Keywords: pediatric ophthalmology; genetic eye diseases; gene therapy; genetic counseling; telemedicine; diagnostic tools; blindness in childhood; congenital cataract; visual rehabilitation; myopia control

(This special issue belongs to the Section Ophthalmology)

Innovations in Neurorehabilitation—2nd Edition

edited by

Syoichi Tashiro

submission deadline 20 Jun 2026 | Viewed by 88 | Submission Open

Keywords: clinical neurophysiology; neuroengineering; robotics; non-invasive transcranial brain stimulation; spinal stimula-tion; regenerative rehabilitation; neuroimaging; brain– computer interface; brain-spinal interface; virtual reality; higher-level cognitive functions; vision rehabilitation

(This special issue belongs to the Section Clinical Rehabilitation)

Obsessive–Compulsive Disorder: Clinical Advances and Future Perspectives—Second Edition

edited by Andrea Fagiolini

submission deadline 20 Jun 2026 | Viewed by 85 | Submission Open

Keywords: obsessions– compulsions; anxiety; OCD symptoms; treatment options; functional impairment

(This special issue belongs to the Section Mental Health)

Clinical Research on Minimally Invasive Spine Surgery

edited by Daniel Fahim

submission deadline 20 Jun 2026 | Viewed by 83 | Submission Open

Keywords: minimally invasive spine surgery; spine tumors; spine trauma; spine fractures; lumbar stenosis; lumbar spondylolisthesis; lumbar disc herniation; lumbar radiculopathy; thoracic disc herniations; cervical radiculopathy

(This special issue belongs to the Section Orthopedics)

Contemporary Issues and Emerging Trends in Colorectal Surgery

edited by

Marco Caricato

and

Gianluca Mascianà

submission deadline 20 Jun 2026 | Viewed by 81 | Submission Open

Keywords: abdominal surgery; minimally invasive surgery; colorectal surgery; colorectal cancer; inflammatory bowel disease; image-guided surgery; transational research; artificial intelligence; operative endoscopy; screening; early diagnosis; ERAS

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Insights in Pediatric Dentistry

edited by

Giulia Orilisi

submission deadline 20 Jun 2026 | Viewed by 80 | Submission Open

Keywords: pediatric dentistry; caries management; dental trauma; preventive dentistry; behavior management; interdisciplinary care; clinical innovations

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Endoscopic Innovations in Gastrointestinal Diseases: From Diagnosis to Therapy

edited by Mattia Brigida and Gianluca Andrisani

submission deadline 20 Jun 2026 | Viewed by 80 | Submission Open

Keywords: endoscopic innovation; gastrointestinal diseases; advanced endoscopic imaging; therapeutic endoscopy; artificial intelligence; minimally invasive therapy; personalized medicine

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Chronic Kidney Disease: From Diagnosis to Treatment

edited by Debra Hain

submission deadline 20 Jun 2026 | Viewed by 77 | Submission Open

Keywords: chronic kidney disease; type 2 diabetes; diabetic complications; hemodialysis; nephrology nursing; older adults; palliative care; therapy; hypertension

(This special issue belongs to the Section Nephrology & Urology)

Current Perspectives and Emerging Trends in Cardiothoracic Surgery

edited by Zsolt Szabo and

Zsolt Molnar

submission deadline 20 Jun 2026 | Viewed by 75 | Submission Open

Keywords: minimally invasive cardiac surgery; minimally invasive thoracic surgery; minimally invasive valve surgery; non-intubated and spontaneous ventilation techniques; thymus surgery; prehabilitation; chronic comorbidities (DM; COPD); cardiopulmonary bypass outcomes; extracorporeal life support (ECLS); emerging trends in cardiothoracic surgery

(This special issue belongs to the Section General Surgery)

Displaying special issue 1251-1300 on page 26 of 32.

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