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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Clinical Trends and Prospects in Urology Surgery: 2nd Edition
edited by
submission deadline 20 May 2026 | Viewed by 69 | Submission Open
Keywords: robotic surgery; laparoscopic surgery; endourology; minimally invasive surgery; artificial intelligence
(This special issue belongs to the Section Nephrology & Urology)
Clinical Advances in Ocular Surgeries: Innovations in Cataract, Retinal, and Beyond
edited by and Yu Cheol Kim
submission deadline 20 May 2026 | Viewed by 68 | Submission Open
Keywords: cataract surgery; retinal surgery; intraocular lenses; femtosecond laser; minimally invasive vitrectomy; ocular imaging; surgical innovation; ocular trauma; corneal transplantation; glaucoma surgery
(This special issue belongs to the Section Ophthalmology)
Advances in Demyelinating and Neuroinflammatory Disorders submission deadline 20 May 2026 | Viewed by 67 | Submission Open
Keywords: multiple sclerosis; neuromyelitis optica spectrum disorder; MOG antibody– associated disease; neuroinflammation; biomarkers; advanced imaging; disease-modifying therapies; clinical outcomes
(This special issue belongs to the Section Clinical Neurology)
Presbyopia, Laser, Cataract and Refractive Surgery: State-of-the-Art Research: Second Edition
edited by
submission deadline 20 May 2026 | Viewed by 67 | Submission Open
Keywords: presbyopia; cataract surgery; refractive surgery; femtosecond laser; intraocular lenses; corneal refractive procedures; phakic intraocular lenses; visual outcomes; patient-reported outcomes; surgical innovations
(This special issue belongs to the Section Ophthalmology)
Clinical Advances in Hemodialysis: 2nd Edition
edited by Maurizio Bossola
submission deadline 20 May 2026 | Viewed by 66 | Submission Open
Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy
(This special issue belongs to the Section Nephrology & Urology)
Alcohol-Associated Liver Disease: Diagnosis and Treatment of Acute and Chronic Conditions
edited by Halina Cichoz-Lach and
submission deadline 20 May 2026 | Viewed by 66 | Submission Open
Keywords: alcohol-associated liver disease; alcohol-associated hepatitis; alcohol-associated liver cirrhosis; excessive alcohol intake; oxidative liver damage; gut– liver axis; organ-to-organ crosstalk
(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)
Cardiomyopathies: A Contemporary Review of Advances and Clinical Strategies
edited by Carla Contaldi
submission deadline 20 May 2026 | Viewed by 65 | Submission Open
Keywords: cardiomyopathies; heart failure; genetic mutations; molecular mechanisms; advanced cardiac imaging; cardiac MRI; precision medicine; risk stratification
(This special issue belongs to the Section Cardiology)
Clinical Updates on Perioperative Pain Management: 3rd Edition submission deadline 20 May 2026 | Viewed by 64 | Submission Open
Keywords: anesthesia and intensive care; pain management; spinal anesthesia; postoperative pain; breast surgery; fascial plane blocks; abdominal surgery; cardiac surgery; thoracotomy; knee surgery; orthopedic surgery; hip surgery; ultrasound
(This special issue belongs to the Section Anesthesiology)
Acute Coronary Syndromes | Circulation Research submission deadline 20 May 2026 | Viewed by 63 | Submission Open
Keywords: acute coronary syndromes; cardiovascular risk; individualized therapy; STEMI; risk factors
(This special issue belongs to the Section Cardiology)
Clinical Research Progress in Atrial Fibrillation
edited by
submission deadline 20 May 2026 | Viewed by 63 | Submission Open
Keywords: atrial fibrillation; atrial arrhythmias; cardiac fibrosis; inflammation; electrical remodeling
(This special issue belongs to the Section Cardiology)
The Current Trend in the Management of Bruxism and Temporomandibular Disorders, 2nd Edition submission deadline 20 May 2026 | Viewed by 62 | Submission Open
Keywords: bruxism; temporomandibular disorders (TMDs); dental health; treatment modalities; diagnosis; clinical interventions
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Perspectives on Obesity and Bariatric Surgery: Outcomes and Complications
edited by Dilhana S. Badurdeen
submission deadline 20 May 2026 | Viewed by 61 | Submission Open
Keywords: obesity; bariatric surgery; metabolic surgery; Roux-en-Y Gastric Bypass (RYGB); sleeve gastrectomy; revisional bariatric surgery; complications; outcomes; weight loss maintenance; metabolic syndrome; type 2 diabetes remission; nutritional deficiencies; gastrointestinal adaptation; quality of life; long-term follow-up
(This special issue belongs to the Section General Surgery)
Acute Medical Threats: Evidence-Driven Strategies in Emergency Medicine submission deadline 20 May 2026 | Viewed by 60 | Submission Open
Keywords: emergency medicine protocols; acute medical care; trauma management; resuscitation; critical care; infectious disease preparedness
(This special issue belongs to the Section Emergency Medicine)
Diagnosis, Monitoring, and Treatment of Myocardial Infarction: 2nd Edition
edited by
submission deadline 20 May 2026 | Viewed by 60 | Submission Open
Keywords: myocardial infarction; diagnosis; monitoring; treatment; acute MI
(This special issue belongs to the Section Cardiovascular Medicine)
Prevention, Treatment, and Prognosis of Cerebral Aneurysms
edited by Murai Yasuo
submission deadline 20 May 2026 | Viewed by 59 | Submission Open
Keywords: cerebral aneurysm; subarachnoid hemorrhage; clipping; interventional surgery; mortarity; long-term; surgical com-plication; bypass
(This special issue belongs to the Section Clinical Neurology)
The Application of Mechanical Circulatory Support Within Cardiology Practice
edited by
submission deadline 20 May 2026 | Viewed by 55 | Submission Open
Keywords: mechanical circulatory support (MCS); cardiogenic shock; intra-aortic balloon pumping (IABP); extracorporeal membranous oxygenation (ECMO); Impella; ventricular assist device (VAD)
(This special issue belongs to the Section Cardiology)
Advances in Diagnosis and Management of Scoliosis
edited by
submission deadline 20 May 2026 | Viewed by 53 | Submission Open
Keywords: scoliosis; spinal deformities; therapeutic strategies; personalized care; quality of life
(This special issue belongs to the Section Orthopedics)
Myocardial Infarction: Current Status and Future Challenges—2nd Edition
edited by Isaac Pascual and
submission deadline 20 May 2026 | Viewed by 52 | Submission Open
Keywords: myocardial infarction; acute coronary syndrome (ACS); ischemic heart disease; coronary artery disease (CAD); percutaneous coronary intervention; pharmacological therapy; cardiovascular risk factors
(This special issue belongs to the Section Cardiology)
Clinical Aspects of Return to Sport After Injuries: 2nd Edition
edited by and
submission deadline 20 May 2026 | Viewed by 52 | Submission Open
Keywords: musculoskeletal system; tissue overload; diagnostic methods; rehabilitation; treatment; injury prevention; return to sport; rehabilitation medicine; sports medicine
(This special issue belongs to the Section Sports Medicine)
Spine Surgery and Rehabilitation: Technical Nuances and Outcomes
edited by Sehan Park and Dong-Ho Lee
submission deadline 20 May 2026 | Viewed by 52 | Submission Open
Keywords: spine surgery; rehabilitation; postoperative outcomes; surgical techniques; patient centered perspective
(This special issue belongs to the Section Orthopedics)
Transcatheter Aortic Valve Implantation and Replacement: Prospects and Challenges—2nd Edition
edited by Konstantinos Toutouzas and
submission deadline 20 May 2026 | Viewed by 48 | Submission Open
Keywords: TAVI; aortic stenosis; valve-in-valve; structural heart disease; TAVI-in-TAVI
(This special issue belongs to the Section Cardiology)
Contemporary Advances in Joint Arthroplasty: Optimizing Outcomes and Expanding Indications submission deadline 20 May 2026 | Viewed by 45 | Submission Open
Keywords: joint arthroplasty; total joint replacement; revision arthroplasty; robotic-assisted surgery; periprosthetic joint infection (PJI); enhanced recovery after surgery (ERAS); machine learning; artifical intelligence
(This special issue belongs to the Section Orthopedics)
Valvular Heart Disease: Current Knowledge and Therapeutic Prospects
edited by Simona Mega
submission deadline 20 May 2026 | Viewed by 44 | Submission Open
Keywords: valvular heart disease; echocardiographic assessment; cardiovascular imaging; valvular regurgitation; valvular stenosis; structural heart intervention; minimally invasive cardiac surgery; catheter-based interventions
(This special issue belongs to the Section Cardiology)
Neurological Surgery: Clinical Advances and AI-Driven Innovations
edited by Ali A. Alattar
submission deadline 20 May 2026 | Viewed by 42 | Submission Open
Keywords: neurosurgery; artificial intelligence; machine learning; deep learning; radiomics; image segmentation; surgical video analytics; navigation and robotics; predictive modeling; clinical decision support
(This special issue belongs to the Section Clinical Neurology)
Foot and Ankle Surgery: Clinical Challenges and New Insights: 2nd Edition
edited by
submission deadline 20 May 2026 | Viewed by 42 | Submission Open
Keywords: hallux valgus; minimal invasive correction; chronic ankle instability; arthroscopic Brostrom procedure; suture-tape augmentation; ankle arthritis; total ankle arthroplasty; ankle arthrodesis
(This special issue belongs to the Section Orthopedics)
Clinical Challenges in Uterus Transplant Management
edited by Giuliano Testa
submission deadline 20 May 2026 | Viewed by 38 | Submission Open
Keywords: uterus transplant; absolute uterine infertility; fertility treatment; immunosuppression in uterus transplant; pregnancy complications; uterine donor evaluation
(This special issue belongs to the Section Obstetrics & Gynecology)
Bladder Cancer: Diagnosis, Treatment and Future Opportunities submission deadline 20 May 2026 | Viewed by 37 | Submission Open
Keywords: urology; bladder cancer; urothelial cancer; non-muscle invasive bladder cancer; muscle invasive bladder cancer
(This special issue belongs to the Section Nephrology & Urology)
Current Understanding and Management of Asthma and Chronic Obstructive Pulmonary Disease
edited by Josuel Ora
submission deadline 20 May 2026 | Viewed by 35 | Submission Open
Keywords: asthma; chronic obstructive pulmonary disease (COPD); personalized medicine; exacerbations; biomarkers; inhalation therapy; digital health; artificial intelligence; pulmonary rehabilitation; comorbidities
(This special issue belongs to the Section Respiratory Medicine)
The Interplay of Trauma Symptoms and Cognitive Functioning: Clinical Implications
edited by and
submission deadline 20 May 2026 | Viewed by 33 | Submission Open
Keywords: trauma; stress; cognitive dysfunction; clinical syndromes; clinical implications
(This special issue belongs to the Section Mental Health)
Audiology and Phoniatrics in Head and Neck Surgery: Functional Assessment, Rehabilitation Strategies, and Quality of Life Outcomes
edited by
submission deadline 20 May 2026 | Viewed by 25 | Submission Open
Keywords: audiology; phoniatrics; voice disorders; hearing preservation; speech rehabilitation; head and neck surgery; functional outcomes; quality of life; voice analysis; audiometry; cochlear implants; dysphagia; laryngeal surgery
(This special issue belongs to the Section Otolaryngology)
Osteoporosis: A Renascent Impact of Vertebral Fractures in the Diagnosis and Management
edited by Csaba Horvath
submission deadline 20 May 2026 | Viewed by 11 | Submission Open
Keywords: osteoporosis; vertebral fractures; imminent fracture risk; FRAX; bone densitometry; vertebral fracture assessment
(This special issue belongs to the Section Orthopedics)
Clinical Features and Management of Psychosis
edited by , and Michael Hadjulis
submission deadline 22 May 2026 | 4 articles | Viewed by 9239 | Submission Open
Keywords: psychosis; clinical features of psychosis; diagnosis of psychosis; schizophrenia; psychotic depression; affective disorder with psychotic features; psychosis in substance use disorders; psychosis in neurological disorders; psychosis in medical conditions; management of psychosis; treatment of psychosis
(This special issue belongs to the Section Mental Health)
Thoracic Surgery: Recent Developments and Future Challenges
edited by and Lucio Cagini
submission deadline 22 May 2026 | 1 articles | Viewed by 2756 | Submission Open
Keywords: VATS; RATS; ERAS; sublobar resection; minimally invasive thoracic surgery; target therapy; nodule localization
(This special issue belongs to the Section Respiratory Medicine)
Clinical Updates on Rheumatoid Arthritis: 2nd Edition
edited by Francesca Bandinelli
submission deadline 22 May 2026 | 1 articles | Viewed by 1530 | Submission Open
Keywords: rheumatoid arthritis; rheumatology; treatment; diagnosis; biomarkers; rheumatic disease
(This special issue belongs to the Section Immunology & Rheumatology)
Takotsubo Syndrome: Insights into Pathophysiology, Diagnosis, and Management submission deadline 22 May 2026 | Viewed by 266 | Submission Open
Keywords: takotsubo syndrome; stress cardiomyopathy; acute heart failure; cardiac imaging; catecholamine surge; myocardial dysfunction; echocardiography; biomarker discovery; cardiovascular risk; clinical management
(This special issue belongs to the Section Cardiology)
Maxillo-Facial Surgery: New Insights and Technologies in Head and Neck
edited by Federica Ruggiero
submission deadline 25 May 2026 | 6 articles | Viewed by 11137 | Submission Open
Keywords: oral and maxilla-facial surgery; orthognathic surgery; cranio-facial surgery; head and neck surgery; augmented reality; navigation; finite element modeling; virtual surgical planning; patient-specific implants
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Preventive, Diagnostic and Therapeutic Strategies for Abdominal Surgery Complications (Second Edition)
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 8839 | Submission Open
Keywords: complications; diagnosis; treatment; management; morbidity; abdomen; abdominal surgery; outcome; postoperative
(This special issue belongs to the Section General Surgery)
Oral and Maxillofacial Surgery: Diagnosis, Management and Future Opportunities
edited by
submission deadline 25 May 2026 | 5 articles | Viewed by 8050 | Submission Open
Keywords: head and neck oncology; free flaps; oral surgery; malformative surgery; traumatology; endoscopy; preprosthetic surgery; reconstructive surgery; vascular malformations; osteonecrosis
(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)
Clinical Diagnosis and Management of Vestibular Disorders
edited by , Mario Habek and
submission deadline 25 May 2026 | 7 articles | Viewed by 7457 | Submission Open
Keywords: vertigo; dizziness; epidemiology; genetics; diagnostics; management
(This special issue belongs to the Section Otolaryngology)
Clinical Utility of Optical Coherence Tomography in Ophthalmology: 2nd Edition submission deadline 25 May 2026 | 4 articles | Viewed by 6766 | Submission Open
Keywords: optical coherence tomography; ophthalmology; intraoperative OCT; en face OCT; wide-field OCT; retinal diseases; glaucoma; cornea; strabismus; cataract
(This special issue belongs to the Section Ophthalmology)
Future Opportunities in Thoracic Surgery: The Cutting Edge: 2nd Edition
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 5439 | Submission Open
Keywords: surgical resection; immunotherapy; target therapy; thoracic surgery; thoracic oncology; lung cancer
(This special issue belongs to the Section Respiratory Medicine)
Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives—2nd Edition
edited by Nikos Nikolettos and
submission deadline 25 May 2026 | 3 articles | Viewed by 3097 | Submission Open
Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF
(This special issue belongs to the Section Reproductive Medicine & Andrology)
The Rebirth of Ventral Skull Base Surgery through Multiportal Approaches: Endonasal, Transorbital, Transmaxillary and Transoral Routes
edited by Matteo de Notaris and Francesco Corrivetti
submission deadline 25 May 2026 | 3 articles | Viewed by 2416 | Submission Open
Keywords: skull base surgery; neuroendoscopy; neuroanatomy; multiportal approaches; technical advancements
(This special issue belongs to the Section Clinical Neurology)
Clinical Highlights in Uveal Melanoma
edited by Tomasz Chorągiewicz and
submission deadline 25 May 2026 | 1 articles | Viewed by 2155 | Submission Open
Keywords: choroidal melanoma; uveal melanoma; radiotherapy; enucleation; brachytherapy
(This special issue belongs to the Section Ophthalmology)
Interstitial Lung Disease Secondary to Autoimmune Disorders: Recent Advances and Novel Perspectives
edited by , and Francesco Ferro
submission deadline 25 May 2026 | 1 articles | Viewed by 1816 | Submission Open
Keywords: interstitial lung disease; lung involvement; connective tissue diseases; rheumatoid arthritis; systemic vasculitis; radiomics; lung ultrasound; biomarkers; pathogenetic immunological pathways; therapeutic targets
(This special issue belongs to the Section Respiratory Medicine)
Advances in the Clinical Management of Perioperative Anesthesia: 2nd Edition
edited by Alessia Mattei, Rita Cataldo and
submission deadline 25 May 2026 | 3 articles | Viewed by 1528 | Submission Open
Keywords: perioperative outcomes (surgical; anesthetic; medical); evidence-based care; perioperative guidelines and consensus statements; preoperative evaluation and risk scores; preoperative testing; surgical optimization and enhanced surgical recovery programs; intensive care unit
(This special issue belongs to the Section Anesthesiology)
Innovative Technologies and Approaches in Eye Disease Management and Refractive Surgery
edited by
submission deadline 25 May 2026 | 1 articles | Viewed by 1420 | Submission Open
Keywords: multifocal intraocular lenses; femtosecond lasers; artificial intelligence; imaging; eye surgery; refractive surgery
(This special issue belongs to the Section Ophthalmology)
Current Clinical Advances in Urinary Incontinence
edited by Adolf Lukanovic, David Lukanović and Mija Blaganje
submission deadline 25 May 2026 | 2 articles | Viewed by 1417 | Submission Open
Keywords: female urinary incontinence; stress urinary incontinence; overactive bladder; diagnosis; prevention; conservative treatment; minimally invasive treatment; surgery; mid-urethral sling; new approach; energy-based devices
(This special issue belongs to the Section Nephrology & Urology)
Diabetic Foot: Emerging Prevention Strategies and Epidemiology submission deadline 25 May 2026 | 1 articles | Viewed by 1161 | Submission Open
Keywords: diabetic foot; foot clinics; epidemiology; prevention; screening; amputation; podiatry
(This special issue belongs to the Section Endocrinology & Metabolism)
Clinical Updates in Reproductive Endocrinology: 2nd Edition
edited by Iwona Bojar and
submission deadline 25 May 2026 | 1 articles | Viewed by 1137 | Submission Open
Keywords: reproductive endocrinology; endocrine diseases in pregnancy; infertility; endocrine diagnostics in infertility; long-term consequences of endocrine disorders; therapy for endocrine disorders
(This special issue belongs to the Section Obstetrics & Gynecology)
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