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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Interventional and Surgical Treatment of Acute and Chronic Pancreatitis

edited by Chirag Desai

submission deadline 25 Feb 2026 | 5 articles | Viewed by 7506 | Submission Open

Keywords: pancreatitis treatment; endoscopic treatment; pancreatic surgery; Whipple; distal pancreatectomy; islet cell auto trans-plant; total pancreatectomy; TPIAT; laparoscopic treatment of pancreatitis; robotic surgery for pancreatitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Knee Arthroplasty Surgery: Management and Future Opportunities: 2nd Edition

edited by

Joaquín Moya-Angeler

and

Francisco Forriol

submission deadline 25 Feb 2026 | 5 articles | Viewed by 7275 | Submission Open

Keywords: knee; knee replacement; knee arthroplasty; knee alignment technique; robotic knee arthroplasty

(This special issue belongs to the Section Orthopedics)

New Advances in Total Knee Arthroplasty

edited by

Carlo Biz

submission deadline 25 Feb 2026 | 4 articles | Viewed by 6832 | Submission Open

Keywords: artificial intelligence; bone tumors; knee joint; knee pain; knee replacement; knee surgery; orthopedic surgery; osteoarthritis; prognostic markers; radiological evaluation

(This special issue belongs to the Section Orthopedics)

Acute Coronary Syndromes: From Diagnosis to Treatment

edited by

Andreas Mitsis

and Christos Eftychiou

submission deadline 25 Feb 2026 | 3 articles | Viewed by 6099 | Submission Open

Keywords: acute coronary syndrome; diagnosis; biomarkers; interventional cardiology; imaging; pharmacotherapy; patient management; health systems; special populations; clinical trials

(This special issue belongs to the Section Cardiology)

New Advances in Keratoplasty

edited by Cristina Bovone

submission deadline 25 Feb 2026 | 3 articles | Viewed by 5882 | Submission Open

Keywords: lamellar keratoplasty; descemet stripping endothelial keratoplasty (DSAEK); descemet membrane endothelial keratoplasty (DMEK); deep anterior lamellar keratoplasty (DALK); keratoconus; corneal dystrophies; bullous keratopathy; anterior segment OCT

(This special issue belongs to the Section Ophthalmology)

Advances in the Management of Cardiac Amyloidosis and Hypertrophic Cardiomyopathy

edited by Ahmed Abuzaid

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4808 | Submission Open

Keywords: cardiac amyloidosis; hypertrophic cardiomyopathy; left ventricular hypertrophy; non-invasive cardiac imaging; heart failure; clinical manifestations

(This special issue belongs to the Section Cardiology)

New Insights into Cardiorenal Metabolic Syndrome

edited by

Caterina Carollo

submission deadline 25 Feb 2026 | 3 articles | Viewed by 4576 | Submission Open

Keywords: cardiorenal medicine; diabetes; chronic renal failure; heart failure; cardiorenal syndrome; nephrocardiology

(This special issue belongs to the Section Cardiovascular Medicine)

Alzheimer’s Disease and Related Disorders: Recent Advances in Prevention, Diagnosis and Therapy

edited by

Daniel H. S. Silverman

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3632 | Submission Open

Keywords: cognition; prodromal; Alzheimer’ s; Alzheimer; dementia; mild cognitive impairment; mild decline in cognition; disease-modifying; amyloid; tau; neuroinflammation; biomarkers; neuroimaging; PET; PET/CT; PET/MRI

(This special issue belongs to the Section Clinical Neurology)

Obesity Surgery—State of the Art

edited by Anna Casajoana

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3276 | Submission Open

Keywords: obesity; bariatric surgery; metabolic surgery; diabetes mellitus type 2; GLP-1

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Recent Advances in Reconstructive Oral and Maxillofacial Surgery

edited by

Luciano Maria Catalfamo

submission deadline 25 Feb 2026 | 2 articles | Viewed by 3115 | Submission Open

Keywords: oral surgery; maxillofacial surgery; new technologies; free flap; reconstructive surgery; artificial intelligence

(This special issue belongs to the Section General Surgery)

Clinical Aspects and Outcomes in Contemporary Colorectal Surgery

edited by

Lior Segev

submission deadline 25 Feb 2026 | 3 articles | Viewed by 2915 | Submission Open

Keywords: colorectal surgery; colorectal cancer; Crohn’ s disease; ulcerative colitis; coloproctology; minimally invasive surgery

(This special issue belongs to the Section General Surgery)

Clinical Research in Palliative Care

edited by Cosimo Chelazzi

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2610 | Submission Open

Keywords: cancer palliative care; total pain; advanced care planning; spiritual care; financial toxicity; cancer-related pain

(This special issue belongs to the Section Clinical Rehabilitation)

Updates in the Orthopedic Management of Foot Disorders: 2nd Edition

edited by

Carlo Biz

and

Pietro Ruggieri

submission deadline 25 Feb 2026 | 2 articles | Viewed by 2369 | Submission Open

Keywords: foot pathologies; diabetic feet; forefoot deformities; oncology surgery; foot tumors; minimally invasive surgery; percutaneous surgery; foot joint arthroscopy; stress fractures

(This special issue belongs to the Section Orthopedics)

Innovations in Advanced Echocardiography

edited by Rebecca T. Hahn and Alexandros Papachristidis

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1606 | Submission Open

Keywords: advanced echocardiography; ultrafast ultrasound; contrast echocardiography; subharmonic aided pressure estima-tion; artificial intelligence; 3D echocardiography

(This special issue belongs to the Section Cardiology)

Non-Small-Cell Lung Cancer: Screening, Diagnosis and Treatment Options in the AI and Omics Era

edited by Miljana Tanić

submission deadline 25 Feb 2026 | 2 articles | Viewed by 1336 | Submission Open

Keywords: lung cancer; NSCLC; radiomics; digital pathology; electronic health records; tumor profiling; AI; machine learning; deep learning; liquid biopsy; early detection; diagnosis; prognosis; therapy; biomarkers; management

(This special issue belongs to the Section Respiratory Medicine)

Helicobacter pylori-Associated Intestinal Diseases and Beyond

edited by

Antonio Facciorusso

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1000 | Submission Open

Keywords: IBD; Hp; stomach; celiac disease; diverticulosis; diverticulitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Recent Advances in Clinical Pharmacology Based on Pharmacokinetics

edited by

Magdalena Cuciureanu

Cristina Ghiciuc

and

Nina Filip

submission deadline 25 Feb 2026 | Viewed by 968 | Submission Open

Keywords: PK/PD modeling; dose optimization; clinical decision-making tools; therapeutic drug monitoring; personalized medicine

(This special issue belongs to the Section Pharmacology)

Hospital-Acquired Infections: Evolving Threats and Epidemiological Insights

edited by

Amir Nutman

submission deadline 25 Feb 2026 | 1 articles | Viewed by 763 | Submission Open

Keywords: hospital-acquired infections; healthcare-associated infections; antimicrobial resistance; multidrug-resistant organisms (MDRO); infection prevention and control; outbreak investigation; patient safety; healthcare epidemiology

(This special issue belongs to the Section Infectious Diseases)

Clinical Advances of Retinal and Vitreous Diseases: Current Status and Prospect

edited by Lorenzo De Angelis, Francesco Barca and Stanislao Rizzo

submission deadline 25 Feb 2026 | 1 articles | Viewed by 501 | Submission Open

Keywords: vitreoretinal surgery; retinal multimodal imaging; gene therapy; retinal diseases; age-related macular degeneration; vascular retinal disease; imaging technologies in ophthalmology

(This special issue belongs to the Section Ophthalmology)

Application of Echocardiography in Clinical Practice

edited by

Shemy Carasso

submission deadline 25 Feb 2026 | 1 articles | Viewed by 294 | Submission Open

Keywords: echocardiography; three-dimensional imaging; mechanical imaging; strain; artificial intelligence; interventional echocardiography; POCUS; hand-held echocardiography; cancer therapy and cardiotoxicity

(This special issue belongs to the Section Cardiovascular Medicine)

Evidence-Based Physiotherapy: Prospects and Challenges

edited by Roman Nowobilski and

Maciej Płaszewski

submission deadline 25 Feb 2026 | Viewed by 242 | Submission Open

Keywords: evidence-based practice; physiotherapy; critique; certainty of evidence; clinical practice guidelines; implementa-tion; clinical settings; clinical practice; clinical processing

(This special issue belongs to the Section Clinical Rehabilitation)

Advancing Clinical Medicine Through Artificial Intelligence (AI) and Digital Technology: 2nd Edition

edited by

Antonio Jorge Forte

Syed Ali Haider

and

Mark Lifson

submission deadline 25 Feb 2026 | Viewed by 242 | Submission Open

Keywords: artificial intelligence; clinical medicine; medical imaging; precision medicine; clinical decision support systems; patient care; healthcare practices; early disease detection; patient outcomes

(This special issue belongs to the Section Intensive Care)

Clinical Research Progress in Diabetes and Cardiovascular Diseases

edited by

Ken-ichi Aihara

submission deadline 25 Feb 2026 | Viewed by 151 | Submission Open

Keywords: diabetes; cardiovascular diseases; risk factor; vascular function; diagnosis; treatment

(This special issue belongs to the Section Cardiovascular Medicine)

Plastic and Reconstructive Surgery: Clinical Advances and Future Opportunities

edited by Rami S Kantar

submission deadline 25 Feb 2026 | Viewed by 129 | Submission Open

Keywords: plastic surgery; reconstructive surgery; cleft lips; palates; post-traumatic reconstruction; facial transplantation; craniofacial surgery; cleft surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Current Advances and Future Perspectives of Sepsis and Septic Shock

edited by Filippo Mearelli and Gianni Biolo

submission deadline 25 Feb 2026 | Viewed by 118 | Submission Open

Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication

(This special issue belongs to the Section Emergency Medicine)

Segmentectomy and Lobectomy in Early-Stage Lung Cancer Management

edited by Yujin Kudo

submission deadline 25 Feb 2026 | Viewed by 114 | Submission Open

Keywords: lung cancer; segmentectomy; lobectomy; thoracic surgery; early-stage NSCLC; oncologic outcomes; pulmonary function; surgical planning

(This special issue belongs to the Section Respiratory Medicine)

Allergic and Eosinophilic Diseases: Diagnosis, Treatment and Management (Second Edition)

edited by Aikaterini Detoraki

submission deadline 25 Feb 2026 | Viewed by 112 | Submission Open

Keywords: allergy; eosinophilic diseases; immunology; clinical immunology; asthma; diagnosis; treatment; management

(This special issue belongs to the Section Immunology & Rheumatology)

Clinical Updates of Diagnosis and Treatment in Chronic Kidney Disease (CKD)

edited by

Juan F. Navarro-González

, Carmen Mora-Fernández and

Javier Donate-Correa

submission deadline 25 Feb 2026 | Viewed by 111 | Submission Open

Keywords: CKD; CKD progression; biomarkers; disease-modifying treatments; diabetic kidney disease; cardiorenal disease; glomerunephritis; genetic kidney diseases

(This special issue belongs to the Section Nephrology & Urology)

Spinal Surgery: Recent Advances and Future Perspectives

edited by

Yoshiharu Kawaguchi

submission deadline 25 Feb 2026 | Viewed by 111 | Submission Open

Keywords: spine surgery; diagnostic technology; AI; images; biomarkers; genetics; robotic surgery; minimum invasive surgery; pain control; VR

(This special issue belongs to the Section Orthopedics)

Clinical Update on the Diagnosis and Treatment of Heart Failure

edited by Giulia Nardi and Alessio Mattesini

submission deadline 26 Feb 2026 | 5 articles | Viewed by 12650 | Submission Open

Keywords: ejection fraction; acute heart failure; multidisciplinary management; right heart failure; left ventricle remodeling systems; HF percutaneous treatment; pharmacotherapy; HF prevention; cardiomyopathies

(This special issue belongs to the Section Cardiovascular Medicine)

Advances in Arrhythmia Diagnosis and Management

edited by Zoltán Csanádi

submission deadline 26 Feb 2026 | 7 articles | Viewed by 9082 | Submission Open

Keywords: catheter ablation; atrial fibrillation; ventricular tachycardia; conduction system pacing; cardiac resynchronization; sudden cardiac death

(This special issue belongs to the Section Cardiology)

Pancreatic Cancer: Novel Strategies of Diagnosis and Treatment

edited by

Camelia Cristina Diaconu

and

Gina Gheorghe

submission deadline 26 Feb 2026 | 2 articles | Viewed by 2552 | Submission Open

Keywords: pancreatic cancer; chronic pancreatitis; pancreatic intraepithelial neoplasia; gastroenterology; clinical innovative diagnostic; clinical treatment strategies

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Orthodontics: State of the Art and Perspectives

edited by

Camelia Szuhanek

and

Irina Nicoleta Zetu

submission deadline 27 Feb 2026 | 9 articles | Viewed by 13170 | Submission Open

Keywords: orthodontics; digital orthodontics; intraoral scanners; facial scanners; treatment planning; interdisciplinary treatment; orthodontic implants

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Unraveling Myopia: Current Science, Clinical Impact, and Future Horizons

edited by Neeraj K Singh and Pablo De Gracia

submission deadline 27 Feb 2026 | 2 articles | Viewed by 2148 | Submission Open

Keywords: accommodation; contact lenses; ophthalmic lenses; myopia progression; epidemiology; myopia control interventions; pharmaceutical treatments; environmental and behavioral risk factors; imaging innovations in myopia

(This special issue belongs to the Section Ophthalmology)

Harnessing Photobiomodulation Light for Therapeutic or Prevention of Human Diseases

edited by

Reem Hanna

submission deadline 28 Feb 2026 | 6 articles | Viewed by 25604 | Submission Open

Keywords: neurorehabilitation; supportive care for cancer; reproductive health; dental and oral diseases; viral and bacterial diseases; wound care; dermatology; sports rehabilitation; bone and musculoskeletal diseases; PBM mechanism; ophthalmology; stem cells and regenerative medicine; pain and addiction management; PBM-tissue interaction

Advances in Child Neurology

edited by

Giuseppina Sgandurra

and

Marco Carotenuto

submission deadline 28 Feb 2026 | 6 articles | Viewed by 17067 | Submission Open

Keywords: pediatric neurological disorders; pediatric sleep disorders; pediatric epilepsy; autoimmune encephalitis; pediatric acute-onset neuropsychiatric syndrome (PANS); pediatric headaches; RASopathies; neurogenetic disorders; developmental coordination disorder (DCD); pedaitric neurological rehabilitation; AI application for diagnosis and therapeutic management of pediatric neurological diseases

(This special issue belongs to the Section Clinical Pediatrics)

Headache Disorders: New Advances in Management and Treatment Strategies: 2nd Edition

edited by

Andreas A. Argyriou

Emmanouil V. Dermitzakis

and

Vikelis Michail

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1957 | Submission Open

Keywords: headache; migraine; cluster headache; tension-type headache; post-traumatic headache; calcitonin gene-related peptide; monoclonal antibodies; preventive therapy; acute treatment; pathophysiology; neuromodulation; pain management; drug development; gepants; ditan

(This special issue belongs to the Section Clinical Neurology)

Tumor Microenvironment—Current Status and Therapeutic Targets

edited by

Rashi Kalra

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1257 | Submission Open

Keywords: tumor microenvironment (TME); cancer immunology; immune checkpoint inhibitors; cancer biology; targeted therapies

(This special issue belongs to the Section Oncology)

Clinical Updates in Cardiovascular Computed Tomography (CT)

edited by

Antonella Meloni

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1198 | Submission Open

Keywords: cardiovascular CT; coronary CTA; plaque imaging; artificial intelligence; low-dose imaging; structural heart disease; cardiac imaging; high-risk plaque; atherosclerosis; coronary artery disease; valve calcification; thrombus detection

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Head and Neck Surgery—2nd Edition

edited by

Gábor Dénes Répássy

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1147 | Submission Open

Keywords: otorhinolaryngology; head and neck surgery; ear surgery; sinonasal surgery; skull base surgery; salivary gland surgery; thyroid gland surgery; head and neck cancer surgery

(This special issue belongs to the Section General Surgery)

Clinical Therapeutic Advances of Mitral Regurgitation

edited by Angelo Squeri

submission deadline 28 Feb 2026 | 2 articles | Viewed by 959 | Submission Open

Keywords: mitral regurgitation; mitral valve prolapse; cardiovascular interventions; heart surgery; echocardiography; mag-netic resonance imaging; computed tomography

(This special issue belongs to the Section Cardiovascular Medicine)

Towards a New Paradigm: Opioid-Free and Opioid-Sparing Strategies in Modern Anesthesia

edited by

Kassiani Theodoraki

submission deadline 28 Feb 2026 | 2 articles | Viewed by 910 | Submission Open

Keywords: opioid-free anesthesia; opioid-sparing strategies; multimodal analgesia; regional anesthesia; non-opioid analgesics; enhanced recovery after surgery (ERAS); perioperative pain management; postoperative analgesia; anesthesia innovation; chronic pain prevention; patient-centered anesthesia; clinical outcomes in anesthesia

(This special issue belongs to the Section Anesthesiology)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 28 Feb 2026 | 2 articles | Viewed by 804 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Clinical Neurology)

New Advances and Clinical Outcomes of Pediatric Endocrinology

edited by

Gerdi Tuli

submission deadline 28 Feb 2026 | Viewed by 352 | Submission Open

Keywords: congenital hypothyroidism; rare bone diseases; growth hormone deficiency; endocrine sequelae of cancer treatments; disorders of sex development; central diabetes insipidus; gender dysphoria

(This special issue belongs to the Section Clinical Pediatrics)

Emerging Therapies: Clinical Trials and Insights in Psoriasis

edited by

Beata Kowalewska

and Elżbieta Krajewska-Kułak

submission deadline 28 Feb 2026 | 1 articles | Viewed by 348 | Submission Open

Keywords: psoriasis; clinical trials; biomarkers; psychodermatology; treatment; modern therapy; individualized therapy

(This special issue belongs to the Section Dermatology)

Current Trends in Urogynecology: 3rd Edition

edited by

Tomasz Rechberger

submission deadline 28 Feb 2026 | 1 articles | Viewed by 346 | Submission Open

Keywords: urogynecological surgery (uterovaginal prolapse; urinary incontinence; fistulas); OAB; pharmacology; physiotherapy; LUTS

(This special issue belongs to the Section Obstetrics & Gynecology)

Epidemiology Associated Risks and Intervention Strategies of Childhood Obesity

edited by

María M. Morales Suárez-Varela

Antonio Castillo-Paredes

and Eduardo Guzmán-Muñoz

submission deadline 28 Feb 2026 | Viewed by 291 | Submission Open

Keywords: childhood obesity; overweight; eating disorders; nutritional programs; psychological interventions; physical activity exercise; sport; physical well-being; mental well-being; quality of life

(This special issue belongs to the Section Clinical Pediatrics)

Hysterectomy Surgery—Recent Developments and Emerging Trends

edited by

Anastasia Prodromidou

Themos Grigoriadis

and Dimitrios Zacharakis

submission deadline 28 Feb 2026 | Viewed by 189 | Submission Open

Keywords: hysterectomy; minimally invasive hysterectomy; robotic surgery; vaginal hysterectomy; surgical innovation; perioperative care

(This special issue belongs to the Section Obstetrics & Gynecology)

Current and Emerging Treatment Options in Chronic Liver Diseases

edited by Chandana B. Herath and Michael Praktiknjo

submission deadline 28 Feb 2026 | Viewed by 188 | Submission Open

Keywords: liver disease; liver fibrosis; liver cirrhosis; portal hypertension; liver cancer; therapies; immunological therapies for liver cancer; diabetic liver; type 2 diabetes and obesity; spontaneous bacterial peritonitis

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Inflammatory Bowel Disease: Clinical Pathogenesis and Management Strategies

edited by

Francesco Colombo

submission deadline 28 Feb 2026 | Viewed by 75 | Submission Open

Keywords: epithelial barrier dysfunction; intestinal microbiota dysbiosis; minimally invasive surgery in IBDs; disease monitoring; perianal disease treatment; surgical complications in IBD; prehabilitation; stoma formation and management; timing of surgery in IBDs; risk stratification for IBD surgery; patient-reported outcomes post-surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Displaying special issue 751-800 on page 16 of 31.

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