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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Management of Pediatric Neuromuscular Diseases

edited by Nicolas Deconinck

submission deadline 20 Apr 2026 | Viewed by 92 | Submission Open

Keywords: pediatric neuromuscular diseases; neuromuscular disorders (NMD); pediatric; genetic NMD; juvenile myasthenia gravis; chronic demyelinating polyneuropathy; next generation sequencing (NGS); spinal muscular atrophy; Duchenne muscular dystrophy; clinical guidelines

(This special issue belongs to the Section Clinical Neurology)

Schizophrenia and Psychotic Disorders: Clinical Updates

edited by Octavian Vasiliu and

Adela Magdalena Ciobanu

submission deadline 20 Apr 2026 | Viewed by 91 | Submission Open

Keywords: schizophrenia spectrum disorder; mobile health apps; antipsychotics; repetitive transcranial magnetic stimulation; artificial intelligence; machine learning; augmented reality; neuroimaging; treatment resistance; quality of life; comorbidities

(This special issue belongs to the Section Mental Health)

Advanced Applications of Magnetic Resonance Imaging (MRI) in Clinical Diagnosis

edited by Francescamaria Donati

submission deadline 20 Apr 2026 | Viewed by 88 | Submission Open

Keywords: magnetic resonance imaging (MRI); clinical diagnosis; high-field MRI; diffusion-weighted imaging (DWI); perfusion MRI (pMRI); artificial intelligence in imaging; diagnostic imaging; early disease detection; disease monitoring; treatment planning

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Recent Management and Future Perspectives on Knee Arthroplasty

edited by

Georgios Komnos

submission deadline 20 Apr 2026 | Viewed by 88 | Submission Open

Keywords: knee arthroplasty; individualized approach; implant designs; robotic-assisted; knee alignment

(This special issue belongs to the Section Orthopedics)

Peritoneal Dialysis and Hemodialysis: Early and Late Outcomes

edited by Keren Cohen-Hagai and

David Pereg

submission deadline 20 Apr 2026 | Viewed by 85 | Submission Open

Keywords: peritoneal dialysis; dialysis; hemodialysis; chronic kidney disease; end-stage renal disease

(This special issue belongs to the Section Nephrology & Urology)

Up-to-Date Orthopedic Treatment and Care for Osteoporotic Fracture of the Elderly

edited by

Oded Hershkovich

and

Raphael Lotan

submission deadline 20 Apr 2026 | Viewed by 84 | Submission Open

Keywords: osteoporotic fractures; elderly patients; orthopedic surgery; minimally invasive techniques; fracture rehabilitation; kyphoplasty

(This special issue belongs to the Section Orthopedics)

Coronary Artery Disease: Recent Developments and Emerging Trends

edited by

Attila Kardos

and Tarun Mittal

submission deadline 20 Apr 2026 | Viewed by 82 | Submission Open

Keywords: coronary atherosclerosis; diagnostic strategies; therapeutic options; timing of intervention; artificial intelligence; novel therapeutic pathways

(This special issue belongs to the Section Cardiology)

Novel Advances in Lower Limb Trauma and Orthopaedic Surgery

edited by Konstantinos Tsikopoulos and

Panagiotis Givissis

submission deadline 20 Apr 2026 | Viewed by 81 | Submission Open

Keywords: lower limb orthopedic surgery; trauma; infection; research

(This special issue belongs to the Section Orthopedics)

Geriatric Fracture Care: Bridging Orthopedics and Gerontology

edited by Tom Knauf and Daphne Asimenia Eschbach

submission deadline 20 Apr 2026 | Viewed by 80 | Submission Open

Keywords: geriatric fracture; proximal femur fractures; hip fracture; geriatric trauma patient; ortho-geriatric treatment; periprosthetic fracture; end of life decision; orthopedic surgery in the elderly

(This special issue belongs to the Section Geriatric Medicine)

Advancements in Minimally Invasive Neurosurgery

edited by Sanjeeva Jeyaretna and Kumar Abhinav

submission deadline 20 Apr 2026 | Viewed by 80 | Submission Open

Keywords: minimally invasive surgery; skull base surgery; neurosurgery; transorbital; endoscopic transnasal

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances in Endodontic Dentistry

edited by

Luciano Giardino

and

Luigi Generali

submission deadline 20 Apr 2026 | Viewed by 77 | Submission Open

Keywords: antimicrobial agents; biofilm; confocal laser scanning microscopy; endodontic materials; irrigants; microbiome; micro-CT; regenerative endodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Female Infertility: Clinical Diagnosis and Treatment—Second Edition

edited by

Laurie Henry

submission deadline 20 Apr 2026 | Viewed by 76 | Submission Open

Keywords: infertility; assisted reproductive techniques; diagnosis; implantation; gametes

(This special issue belongs to the Section Obstetrics & Gynecology)

Clinical Advances in Risk Minimization Through Robot-Assisted Surgery

edited by Radko Komadina

submission deadline 20 Apr 2026 | Viewed by 71 | Submission Open

Keywords: robot-assisted technology; robotic surgery; laparoscopic surgery; spinal surgery; robot-assisted gynecological operations; robot-assisted operations in urology; robot-assisted prostatectomy

(This special issue belongs to the Section General Surgery)

New Advances in Orthopedic Knee Joint Preserving and Reconstructive Surgery

edited by

Dong Jin Ryu

and

Sung-Sahn Lee

submission deadline 20 Apr 2026 | Viewed by 69 | Submission Open

Keywords: cartilage regeneration; patient-specific instrumentation; knee robotic surgery; patient-specific surgical device; future orthopedics

(This special issue belongs to the Section Orthopedics)

Recent Advancements in Nuclear Medicine and Radiology: 2nd Edition

edited by Adriaan A. Lammertsma

submission deadline 20 Apr 2026 | Viewed by 67 | Submission Open

Keywords: PET; SPECT; CT; MRI; AI; image analysis; kinetic analysis

(This special issue belongs to the Section Nuclear Medicine & Radiology)

New Insights into Breast Neoplasms: Prevention, Multidisciplinary Management and Beyond the Core Team

edited by

Marco Materazzo

and

Antonia Girardi

submission deadline 20 Apr 2026 | Viewed by 67 | Submission Open

Keywords: breast cancer; tumor heterogeneity; estrogen receptor; progesterone receptor; triple-negative breast cancer; metastasis; immunotherapy; targeted therapy; early detection; prognosis; adjuvant treatment

(This special issue belongs to the Section Oncology)

New Sights in Retinal Diseases Therapeutics: Innovation and Clinical Practice

edited by

Giacomo Boscia

Pasquale Viggiano

, Stefano Dore and Alfonso Savastano

submission deadline 20 Apr 2026 | Viewed by 64 | Submission Open

Keywords: retinal diseases; central serous chorioretinopathy; age-related macular degeneration; eye diseases; diabetic retinopathy

(This special issue belongs to the Section Ophthalmology)

Insights from Cardiopulmonary Exercise Testing to Cardiac Rehabilitation

edited by

Gaia Cattadori

submission deadline 20 Apr 2026 | Viewed by 64 | Submission Open

Keywords: cardiac rehabilitation; exercise physiology; exercise performance; exercise testing; physical activity assessment; exercise; physical activity; oxygen consumption; cardiopulmonary exercise testing

(This special issue belongs to the Section Cardiology)

Clinical Research on Pulmonary Hypertension and Its Complications

edited by Gabor G. Kovacs and

Anna Birnhuber

submission deadline 20 Apr 2026 | Viewed by 59 | Submission Open

Keywords: pulmonary hypertension; PH; pulmonary arterial pressure; different diagnostic; therapeutic challenges

(This special issue belongs to the Section Respiratory Medicine)

Innovations in Surgical and Medical Approaches of Urologic Oncology

edited by

Sung Han Kim

submission deadline 20 Apr 2026 | Viewed by 58 | Submission Open

Keywords: urologic oncology; robotic surgery; immunotherapy; targeted therapy; image-guided techniques; personalized medicine; minimally invasive surgery; focal therapy

(This special issue belongs to the Section Nephrology & Urology)

Clinical Cardiac Rehabilitation: Integrating Multidimensional Approaches for Enhanced Cardiovascular Health

edited by

Gaia Cattadori

submission deadline 20 Apr 2026 | Viewed by 58 | Submission Open

Keywords: cardiac rehabilitation; multidimensional approach; integrating approach; cardiovascular health; primary and secondary prevention

(This special issue belongs to the Section Clinical Rehabilitation)

Spinal Cord Injury in Elderly People: Prevention of Complications

edited by Vaidyanathan Subramanian

submission deadline 20 Apr 2026 | Viewed by 54 | Submission Open

Keywords: spinal cord injury; demography; morbidities; complications; spinal injuries; patients; family members; caregivers; general practitioners; discharge; elderly

(This special issue belongs to the Section Geriatric Medicine)

New Challenges and Perspectives in Surgical Treatment of Spinal Deformity

edited by Jung-Hee Lee

submission deadline 20 Apr 2026 | Viewed by 51 | Submission Open

Keywords: adult spinal deformity; decompensation; kyphosis; lateral lumbar interbody fusion; orthopedic surgery; osteotomy; proximal junctional kyphosis; rod fracture

(This special issue belongs to the Section Orthopedics)

Aiming for Early Detection and Prevention of Pulmonary Diseases

edited by

Nektarios Anagnostopoulos

and

Kostas A. Papavassiliou

submission deadline 20 Apr 2026 | Viewed by 40 | Submission Open

Keywords: early diagnosis; prevention strategies; respiratory diseases; artificial intelligence; asthma; chronic obstructive pulmonary disease (COPD); interstitial lung disease; sleep-disordered breathing

(This special issue belongs to the Section Respiratory Medicine)

What Part Do Circulating Tumor Cells Play in Cancers？

edited by

Monika Pizon

and

Katharina Pachmann

submission deadline 20 Apr 2026 | Viewed by 26 | Submission Open

Keywords: circulating tumor cells (CTCs); circulating cancer stem cells (cCSCs); liquid biopsy; therapy monitoring; metastasis; cancer progression

(This special issue belongs to the Section Oncology)

Genitourinary Tumors and Radiation Therapy: Current Advances and Future Directions

edited by Shalini Moningi

submission deadline 20 Apr 2026 | Viewed by 17 | Submission Open

Keywords: cancer; prostate cancer; bladder cancer; kidney cancer; radiation therapy

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Clinical Management of Knee Arthroplasty

edited by

Sang-Hoon Park

submission deadline 21 Apr 2026 | 1 articles | Viewed by 717 | Submission Open

Keywords: knee surgery; knee arthroplasty; knee joint replacement; osteoarthritis; knee arthritis

(This special issue belongs to the Section Orthopedics)

Controversies in Hidradenitis Suppurativa: Bridging Gaps in Science and Practice

edited by Hadar Lev-Tov and Tammy González

submission deadline 21 Apr 2026 | Viewed by 102 | Submission Open

Keywords: hidradenitis suppurativa (HS); inflammatory skin disorder; controversies; treatment strategies; science and practice

(This special issue belongs to the Section Dermatology)

Paediatric Anaesthesia: Clinical Updates and Perspectives

edited by Peter Marhofer, Philipp Opfermann and Markus Zadrazil

submission deadline 24 Apr 2026 | 7 articles | Viewed by 8729 | Submission Open

Keywords: pediatric anesthesia; anesthesia; conduction; ultrasonography; conscious sedation; deep sedation; drug-related side effects and adverse reactions; neurotoxicity syndromes

(This special issue belongs to the Section Anesthesiology)

Challenges and Advances in Geriatrics and Gerontology

edited by Elisa Fabbri

submission deadline 24 Apr 2026 | 3 articles | Viewed by 1946 | Submission Open

Keywords: aging; geriatric medicine; frailty; multimorbidity; sarcopenia; cognition; personalized-care; healthy longevity; decision making-management; prevention; artificial intelligence

(This special issue belongs to the Section Geriatric Medicine)

Advances in Spine Surgery: Current Innovations and Future Directions

edited by

Gonzalo Mariscal

and Jesús Burgos

submission deadline 24 Apr 2026 | Viewed by 124 | Submission Open

Keywords: spine; clinical studies; robotics; minimally invasive; complications; patient-reported outcomes; reviews

(This special issue belongs to the Section Orthopedics)

Innovations and Challenges in Clinical Toxicology and Therapeutic Drug Monitoring

edited by Zhicheng Jin

submission deadline 25 Apr 2026 | 2 articles | Viewed by 19851 | Submission Open

Keywords: toxicology screen; therapeutic drug monitoring; mass spectrometry; immunoassays; pain management; opioids

(This special issue belongs to the Section Pharmacology)

General Anesthesia: Recent Developments and Emerging Trends

edited by Basavana Goudra

submission deadline 25 Apr 2026 | 3 articles | Viewed by 15772 | Submission Open

Keywords: general anesthesia; recent advances; drug development; memory and awareness; brain monitoring; sugammadex; tegileridine

(This special issue belongs to the Section Anesthesiology)

Clinical Management of Oral Healthcare in Diverse Patient Populations: Second Edition

edited by

Antonella Polimeni

and

Iole Vozza

submission deadline 25 Apr 2026 | 8 articles | Viewed by 13888 | Submission Open

Keywords: special needs patients; oral healthcare; pediatric dentistry; dental hygiene; oral pathology; orthodontics; periodontics

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Clinical Perspectives on Surgical Management of Knee Injuries

edited by Min Jung

submission deadline 25 Apr 2026 | 6 articles | Viewed by 10576 | Submission Open

Keywords: osteoarthritis; meniscal repair; ligament reconstruction; cartilage restoration; knee surgery

(This special issue belongs to the Section Orthopedics)

Clinical Insights into Pulmonary Hypertension

edited by Simon Schneider

submission deadline 25 Apr 2026 | 5 articles | Viewed by 9996 | Submission Open

Keywords: pulmonary hypertension; pulmonary vascular disease (PVD); pulmonary arterial hypertension (PAH); chronic thromboembolic pulmonary hypertension (CTEPH); interstitial lung disease; chronic obstructive pulmonary disease (COPD); chronic pulmonary fibrosis; emphysema; respiratory disease; physiology; diagnosis; treatment; rehabilitation; altitude research

(This special issue belongs to the Section Respiratory Medicine)

Clinical Advances in Abdominal Surgery

edited by

Juan José Segura-Sampedro

and César P. Ramírez-Plaza

submission deadline 25 Apr 2026 | 5 articles | Viewed by 6463 | Submission Open

Keywords: abdominal surgery; oncologic surgery; minimal invasive techniques; HIPEC; PIPAC; peritoneal carcinomatosis; liver metastasis

(This special issue belongs to the Section General Surgery)

Assessment and Treatment of Trauma Patients

edited by

Arne Driessen

submission deadline 25 Apr 2026 | 2 articles | Viewed by 6378 | Submission Open

Keywords: trauma surgery; prehospital detection of trauma; assessment of trauma; trauma scale; trauma evaluation; trauma surgery

(This special issue belongs to the Section Emergency Medicine)

Innovations in Perioperative Anesthesia and Intensive Care

edited by

Ivan Gornik

and Ileana Lulic

submission deadline 25 Apr 2026 | 4 articles | Viewed by 5160 | Submission Open

Keywords: perioperative anesthesia; intensive care; artificial intelligence in anesthesia; precision medicine in perioperative care; hemodynamic monitoring; multimodal analgesia; opioid-free anesthesia; ventilation strategies in ICU and surgery; neuromonitoring and sedation; perioperative resuscitation and ECMO

(This special issue belongs to the Section Intensive Care)

Advances in Structural Heart Diseases

edited by

Konstantinos Papadopoulos

Ignatios Ikonomidis

and Erwan Donal

submission deadline 25 Apr 2026 | 2 articles | Viewed by 5144 | Submission Open

Keywords: valvular heart diseases; transcatheter interventions; TEER; LAA closure; ASD closure; interventional echocardiography; multimodality cardiac imaging; three-dimensional echocardiography

(This special issue belongs to the Section Cardiovascular Medicine)

Hand Surgery: Latest Advances and Prospects

edited by

Camillo Fulchignoni

and Lorenzo Rocchi

submission deadline 25 Apr 2026 | 3 articles | Viewed by 4917 | Submission Open

Keywords: hand surgery; musculoskeletal and nerve disorders; innovative surgical procedures; minimally invasive techniques; rehabilitation strategies; robotic surgery

(This special issue belongs to the Section Orthopedics)

Experience and New Application in Otolaryngology and Maxillofacial Surgery

edited by Riccardo Nocini

submission deadline 25 Apr 2026 | 1 articles | Viewed by 3798 | Submission Open

Keywords: new surgical techniques; robotics; endoscopy; revascularized free flaps; innovation; 3D surgical planning.

(This special issue belongs to the Section Otolaryngology)

Advances in the Diagnosis and Treatment of Skin Cancer

edited by

Konstantinos Lallas

and

Aimilios Lallas

submission deadline 25 Apr 2026 | 2 articles | Viewed by 2571 | Submission Open

Keywords: skin cancer; melanoma; keratinocyte carcinoma; basal cell carcinoma; squamous cell carcinoma; biomarkers; immuno-therapy; prognosis

(This special issue belongs to the Section Oncology)

Catheter Ablation of Atrial Fibrillation: Current Progress and New Challenges

edited by Sorin Stefan Popescu, Roland Richard Tilz and Karl-Heinz Kuck

submission deadline 25 Apr 2026 | 2 articles | Viewed by 2316 | Submission Open

Keywords: atrial fibrillation; novel technologies; pulmonary vein isolation; same-day discharge; pulsed field ablation; cryo-ablation; radiofrequency; safety; efficacy; sustainability

(This special issue belongs to the Section Cardiology)

Interventional Cardiology: Recent Advances and Future Perspectives

edited by Cristina Aurigemma and Luigi Cappannoli

submission deadline 25 Apr 2026 | 3 articles | Viewed by 2021 | Submission Open

Keywords: interventional cardiology; percutaneous coronary intervention (PCI); transcatheter aortic valve implantation (TAVI); structural heart disease; coronary artery disease; imaging and artificial intelligence; antithrombotic therapy; future technologies in cardiology; personalized cardiovascular care; minimally invasive interventions

(This special issue belongs to the Section Cardiology)

Current Trends and Future Prospects in Autoantibodies in Liver Diseases

edited by Takashi Himoto

submission deadline 25 Apr 2026 | 1 articles | Viewed by 2016 | Submission Open

Keywords: liver-specific autoantibodies; non-organ-specific autoantibodies; autoimmune liver disease; diagnosis; disease activity; treatment outcome; prognosis; virus-induced autoimmunity; drug-induced autoimmunity

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Endoscopic Diagnosis and Treatments of Gastrointestinal Diseases

edited by Madalina Ilie and Mihai Ciocîrlan

submission deadline 25 Apr 2026 | 3 articles | Viewed by 1976 | Submission Open

Keywords: esogastric lesions; pancreatic diseases; colorectal lesions; hepatobiliary diseases; optical endoscopy; endoscopic ultrasound; upper and lower endoscopy; endoscopic retrograde cholangiopancreatography

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Endometriosis and Endometrial Cancer: Challenge and Clinical Management

edited by

Bogdan Obrzut

, Tomasz Kluz and Bernhard Krämer

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1965 | Submission Open

Keywords: endometriosis; endometrial cancer; non-invasive diagnosis; molecular profiling; surgical techniques; medical treatment; alternative therapies

(This special issue belongs to the Section Obstetrics & Gynecology)

Cardiac Magnetic Resonance Imaging: Current Techniques and Future Directions

edited by Ioannis Botis and

Theodoros D. Karamitsos

submission deadline 25 Apr 2026 | 1 articles | Viewed by 1586 | Submission Open

Keywords: cardiac magnetic resonance imaging; cardiovascular magnetic resonance; cardiac imaging; multimodality imaging; parametric mapping; late gadolinium enhancement; myocardial perfusion; myocardial viability; cardiomyopathies; heart failure

(This special issue belongs to the Section Cardiology)

New Advances in Procedures for the Diagnosis and Treatment of Cardiovascular Disease

edited by

Alexandru Burlacu

and

Adrian Covic

submission deadline 25 Apr 2026 | Viewed by 1373 | Submission Open

Keywords: cardiovascular disease; diagnostic procedures; therapeutic advancements; minimally invasive interventions; precision medicine; imaging technologies; catheter-based treatments; translational research; interventional cardiology; clinical innovations

(This special issue belongs to the Section Cardiovascular Medicine)

Displaying special issue 1151-1200 on page 24 of 31.

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