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Cardio-Oncology: Novel Concepts in Diagnosis, Prevention and Treatment of Cardiotoxicity, from Gender Differences and Beyond (Second Edition)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 578

Special Issue Editors


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Guest Editor
Department of Neuroscience, Imaging and Clinical Sciences, University of Chieti-Pescara, Chieti, Italy
Interests: echocardiography; heart failure; blood pressure; clinical cardiology; cardiac function; cardiomyopathies; atherosclerosis; cardiovascular medicine; cardiovascular physiology; chronic heart failure
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Cardiovascular Sciences, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy
Interests: congenital heart disease; pediatric cardiology; gender medicine; physical exercise; speckle-tracking echocardiography; multi-modality imaging; cardiomyopathy; cardio-oncology; cardiac surgery; heart failure
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Significant improvements in recent decades in the diagnosis and therapy of a variety of cancers have profoundly transformed several neoplasms, from incurable conditions to chronic diseases. On the other hand, therapeutic advances have led to increased morbidity and mortality due to treatment side effects. In this clinical scenario, cardiovascular (CV) disease is evolving as a crucial cause of morbidity and death in many cancer survivors. The latter may be the result of cardiotoxicity as well as the enhanced development of CV disease, especially in the presence of traditional CV risk factors. Moreover, CVD and cancer share several overlapping risk factors such as age, tobacco habit, obesity, and sedentary behavior. Cardio-oncology represents a relatively new subspecialty focusing on the diagnosis, prevention, and treatment of CV complications related to cancer and its therapy. Gender differences are well known in oncological and CV diseases, but to date, they are still less enlightened in cardio-oncological scenarios. Following the success of the first volume of “Cardio-Oncology: Novel Concepts in Diagnosis, Prevention and Treatment of Cardiotoxicity, from Gender Differences and Beyond” (https://www.mdpi.com/journal/jcm/special_issues/Cardio_Oncology_Cardiotoxicity), we here announce the second volume of this Special Issue with the aim of highlighting recent advances in gender differences, prevention, diagnosis, treatment, and prognosis in cardio-oncology.

Prof. Dr. Sabina Gallina
Dr. Valentina Bucciarelli
Guest Editors

Manuscript Submission Information

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Keywords

  • cardio-oncology
  • cardiotoxicity
  • gender medicine
  • chemotherapy
  • radiotherapy
  • immune and targeted therapeutics
  • physical activity
  • quality of life

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Published Papers (1 paper)

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Review

26 pages, 368 KiB  
Review
Exercise Prescription in Cardio-Oncology
by Nicola Campana, Luca Fazzini, Clelia Donisi, Alessandro Nava, Michele Migliari, Martino Deidda, Andrea Pretta, Mario Scartozzi and Christian Cadeddu Dessalvi
J. Clin. Med. 2025, 14(11), 3724; https://doi.org/10.3390/jcm14113724 - 26 May 2025
Viewed by 63
Abstract
Numerous studies underscore the benefits of exercise prescription in both cardiology and oncology. Recently, emerging eviAlessandro Navadence has highlighted the value of exercise in cardio-oncology, demonstrating its protective effects against the decline in functional capacity and cardiovascular complications that may arise in oncology [...] Read more.
Numerous studies underscore the benefits of exercise prescription in both cardiology and oncology. Recently, emerging eviAlessandro Navadence has highlighted the value of exercise in cardio-oncology, demonstrating its protective effects against the decline in functional capacity and cardiovascular complications that may arise in oncology patients, either as a result of the disease itself or as a side effect of chemotherapy. The purpose of this review is to elucidate the protective mechanisms and cardiovascular clinical benefits conferred by exercise prescription in cancer patients. Additionally, it aims to delineate the principal current exercise protocols that have been validated or proposed, outlining their respective advantages and limitations. Finally, we will explore future perspectives, particularly the development of precision medicine, supported by advancements in AI, to facilitate the creation of novel, personalized exercise protocols tailored to specific patient populations. Full article
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