Clinical Management of Salivary Gland Disorders

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 20 August 2025 | Viewed by 567

Special Issue Editor


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Guest Editor
Department of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Osaka 573-1010, Japan
Interests: head and neck surgery; ENT; otology; endoscopic surgery

Special Issue Information

Dear Colleagues,

Parotidectomy, the surgical removal of lesions, mainly tumours, in the parotid gland, has long been a challenge in terms of the accurate resection of the lesion and minimizing complications. Although not common in other organs, the parotid gland has an internal branching of the facial nerve, thus requiring delicate manipulation to preserve it. The histopathological variety of salivary gland tumours also makes diagnosis and treatment more difficult. Even with the development of nerve monitoring devices, preservation of function is occasionally difficult. Therefore, preoperative and intraoperative diagnosis, especially histopathological characterization, is very important in the handling of the nerves. The challenges in salivary gland treatment are diverse, including surgical techniques, imaging, and pathology, and their development is essential for safe treatment. In addition to surgical treatment, future advances in molecular-targeted therapy and immunotherapy are also promising. In this Special Issue, we welcome authors to submit papers on the clinical advances of salivary gland lesions in terms of both diagnosis and treatment.

Prof. Dr. Masao Yagi
Guest Editor

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Keywords

  • salivary gland tumour
  • parotidectomy
  • nerve monitoring
  • molecular-targeted therapy
  • immunotherapy

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Published Papers (1 paper)

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Research

20 pages, 1081 KiB  
Article
Minimally Invasive Interventions in Obstructive and Inflammatory Salivary Gland Diseases: Local Anesthesia Based Pain Management, Stratification of Invasiveness, and Patients’ Perceptions
by Mirco Schapher, Maximilian Traxdorf, Heinrich Iro and Michael Koch
J. Clin. Med. 2025, 14(6), 1797; https://doi.org/10.3390/jcm14061797 - 7 Mar 2025
Viewed by 389
Abstract
Objectives: Since the peri- and intraoperative management of patients with inflammatory and obstructive sialadenitis (IOS) differs significantly between treating centers worldwide, we investigated whether these patients can be treated successfully, resource-savingly and with high patient satisfaction using minimally invasive procedures under local anesthesia [...] Read more.
Objectives: Since the peri- and intraoperative management of patients with inflammatory and obstructive sialadenitis (IOS) differs significantly between treating centers worldwide, we investigated whether these patients can be treated successfully, resource-savingly and with high patient satisfaction using minimally invasive procedures under local anesthesia (LA). Methods: We developed a comprehensive, stratified routine anesthesia and pain management protocol based on our proposed classification of invasiveness (grade 1–4), for almost all available IOS treatment procedures. We included 377 patients with 470 LA-conducted interventions in our study and evaluated their perceptions during and after the treatment. Results: The protocol was applied to all 377 study participants for all 470 interventions. The mean grade of invasiveness was 2.49 ± 1.31, with a mean procedure duration of 30 ± 20 min. We found a significant positive association between invasiveness levels and procedure duration (p = 0.001) or pain directly after surgery (p = 0.004). Patients rated the procedures as ”well acceptable” or better in a large majority (88.1–97%) regarding the administration and potency of LA, procedure duration, and pain during and directly after surgery. In total, 96.4% of patients would have the treatment repeated under the same conditions. Conclusions: The proposed anesthesia and pain management regimen, respecting invasiveness levels, enables IOS patients to undergo treatment under LA with high success rates, serving as a potential guide for performing physicians. Full article
(This article belongs to the Special Issue Clinical Management of Salivary Gland Disorders)
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