Catheter Ablation for Cardiac Arrhythmias: Clinical Updates and Perspectives in Cardiac Electrophysiology

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: 21 August 2025 | Viewed by 2210

Special Issue Editors


E-Mail Website
Guest Editor
Department of Cardiology, Ulm University Heart Center, Albert-Einstein-Allee 23, 89081 Ulm, Germany
Interests: electrophysiology; atrial fibrillation; ablation; 3D mapping; pulsed field ablation sudden cardiac death; genetic cardiomyopathy

E-Mail Website
Guest Editor
Department of Cardiology, Ulm University Heart Center, Albert-Einstein-Allee 23, 89081 Ulm, Germany
Interests: electrophysiology; atrial fibrillation; atrial remodeling; long QT syndrome; sudden cardiac deat

E-Mail Website
Guest Editor Assistant
Department of Electrophysiology, Heart Center at the University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany
Interests: electrophysiology; ablation; atrial fibrillation; sudden cardiac death; ventricular arrhythmias; cardiac implantable electronic devices

Special Issue Information

Dear Colleagues,

Cardiac electrophysiology is a rapidly evolving field. Today, catheter ablation stands as the first-line therapy for many cardiac arrhythmias, such as AV node reentry tachycardia, typical and atypical atrial flutter, and atrial fibrillation. Pulmonary vein isolation (PVI) is the most frequently performed ablation procedure in cardiac electrophysiology and a pivotal strategy in the rhythm management of atrial fibrillation patients. Over the past decades, various thermal and non-thermal modalities for cardiac catheter ablation have emerged. These include 3D mapping-integrated point-by-point radiofrequency ablation, single-shot cryoballoon PVI, and pulsed-field ablation. Additionally, ablation procedures for premature ventricular contractions (PVCs) and ventricular tachycardia (VT) have significantly improved outcomes for these complex arrhythmias. With a deeper understanding of arrhythmic substrates, modulators, and triggers, substrate-based ablation is gaining increasing attention. This Special Issue aims to provide clinical updates and perspectives on the rapidly evolving cardiac arrhythmia catheter ablation field.

Dr. Karolina Weinmann-Emhardt
Dr. Ingo Staudacher
Guest Editors

Dr. Jonas Wormann
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrophysiology
  • arrhythmia
  • atrial fibrillation
  • atrial flutter
  • ablation
  • 3D mapping
  • pulsed field ablation
  • radiofrequency ablation
  • pulmonary vein isolation

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 3410 KiB  
Article
Comparative Analysis of Real-World Clinical Outcomes of a Novel Pulsed Field Ablation System for Pulmonary Vein Isolation: The Prospective CIRCLE-PVI Study
by Lyuboslav Katov, Yannick Teumer, Carlo Bothner, Wolfgang Rottbauer and Karolina Weinmann-Emhardt
J. Clin. Med. 2024, 13(23), 7040; https://doi.org/10.3390/jcm13237040 - 21 Nov 2024
Viewed by 1853
Abstract
Background: Pulsed field ablation (PFA) represents a novel non-thermal approach for treating atrial fibrillation (AF) through pulmonary vein isolation (PVI). By utilizing irreversible electroporation, PFA creates lesions with minimal impact on adjacent tissues. This study investigates the procedural outcomes and safety of a [...] Read more.
Background: Pulsed field ablation (PFA) represents a novel non-thermal approach for treating atrial fibrillation (AF) through pulmonary vein isolation (PVI). By utilizing irreversible electroporation, PFA creates lesions with minimal impact on adjacent tissues. This study investigates the procedural outcomes and safety of a novel circular PFA catheter in comparison to an established PFA system in a real-world clinical setting. Methods: This prospective, single-center study enrolled 125 consecutive patients with symptomatic paroxysmal or persistent AF undergoing first-time PVI with PFA at Ulm University Heart Center. Twenty-five patients underwent PFA PVI using a novel PFA system (PulseSelectTM, Medtronic, Dublin, Ireland) which incorporates a new circular catheter design and additional features such as ECG-triggered energy application and phrenic nerve capture testing. In comparison, 100 patients were treated using the established PFA system (FarapulseTM, Boston Scientific, Marlborough, MA, USA). Results: Acute PVI was achieved in 100% of the patients. Procedure duration, total left atrial (LA) time and fluoroscopy time remained comparable between both groups. The total number of energy deliveries was higher with the novel circular PFA catheter (34.0 vs. 32.0; p < 0.001). No procedure-related complications, including pericardial tamponade, phrenic nerve injury, atrial-esophageal fistula, vascular complications, embolisms, malignant cardiac arrhythmias, or coronary spasms were observed. Conclusions: The novel and the established PFA systems demonstrated comparable results in terms of procedure duration, fluoroscopy time, and LA time. In the hands of experienced operators, the novel circular PFA system enables an effective, consistent, and safe approach to successful PFA PVI. Full article
Show Figures

Figure 1

Back to TopTop