25th Anniversary of IJMS: Updates and Advances in Molecular Neurobiology
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 51
Special Issue Editor
Interests: stem cell; Alzheimer’s disease; neurodegenerative diseases; down syndrome; regeneration therapy; cancer stem cell; exosome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The field of molecular neurobiology has undergone a remarkable transformation over the past 25 years, driven by rapid technological advances and deepening insights into the fundamental mechanisms governing brain development, function, and disease. In celebration of the 25th anniversary of the International Journal of Molecular Sciences (IJMS), this Special Issue, “25th Anniversary of IJMS: Updates and Advances in Molecular Neurobiology”, aims to highlight the latest developments, unresolved questions, and future directions in this dynamic and interdisciplinary area of research.
We welcome contributions that explore molecular and cellular processes underlying neural function and dysfunction. Topics of interest include but are not limited to the following: intracellular and intercellular signaling in neurons and glia, transcriptional and epigenetic regulation of neural gene expression, mechanisms of synaptic plasticity, protein misfolding and aggregation, neuroinflammatory cascades, and cell death pathways in neurodegenerative conditions. Additionally, we encourage submissions addressing the roles of non-coding RNAs, exosomes, ion channels, mitochondrial dysfunction, and the molecular basis of neuron–glia interactions.
This Special Issue also welcomes advances in cutting-edge methodologies—such as single-cell omics, CRISPR-based genome editing, optogenetics, and molecular imaging techniques—that provide new windows into the complexity of the nervous system at molecular resolution. Furthermore, we encourage translational studies that bridge molecular mechanisms with clinical applications, including biomarker discovery, drug development, and therapeutic strategies for neurodegenerative and neurodevelopmental disorders.
As we reflect on the progress made since the founding of IJMS, we look forward to contributions that not only celebrate past achievements but also illuminate emerging trends and critical challenges in molecular neurobiology. We invite researchers from basic science, clinical neuroscience, bioengineering, and related fields to join us in marking this milestone and shaping the future of brain research.
Prof. Dr. Kiminobu Sugaya
Guest Editor
Manuscript Submission Information
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Keywords
- molecular neurobiology
- neural signaling and gene regulation
- synaptic plasticity
- neurodevelopment
- neurodegeneration
- neuroregeneration
- neuroinflammation
- epigenetics in neuroscience
- non-coding RNAs
- protein misfolding and aggregation
- exosomes and extracellular vesicles
- stem cells and neural repair
- biomarkers of neurological disease
- translational neuroscience
- neuropharmacology
- brain omics (genomics, proteomics, transcriptomics)
- neuronal-glial interactions
- mitochondrial dysfunction in the nervous system
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