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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Structure-Based Design of Drugs and Other Bioactive Molecules

edited by

Antonio Carrieri

submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open

Keywords: three-dimensional structure; molecular descriptor; molecular similarity; database searching; drug repositioning; target fishing; novel algorithm; data prediction

(This special issue belongs to the Section Molecular Informatics)

Molecular Horizons in Pain Therapeutics

edited by Alaa Abd-Elsayed

submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open

Keywords: spinal cord stimulation; peripheral nerve stimulation; stem cell therapy; platelet-rich plasma (PRP) injections; chronic pain management; interventional pain procedure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Multifunctional Nano-Coatings for Biomedical Applications

edited by

Mikhail Kryuchkov

and Jana Valnohova

submission deadline 30 Sep 2025 | Viewed by 60 | Submission Open

Keywords: nanocoatings; nanomedicine; drug delivery; surface functionalization; diagnostics; therapeutics; prevention; stimuli-responsive materials; biomedical nanotechnology; targeted delivery systems; biocompatible coatings

(This special issue belongs to the Section Molecular Nanoscience)

Intercellular Adhesion and Inflammatory Response in Cancer

edited by Anna Pryczynicz

submission deadline 30 Sep 2025 | Viewed by 59 | Submission Open

Keywords: adhesion; cancer; cancer therapy; inflammation; microenvironment

(This special issue belongs to the Section Molecular Biology)

Novel Genotypes and Experimental Advances in Xenotransplantation

edited by Konrad Fischer

submission deadline 30 Sep 2025 | Viewed by 58 | Submission Open

Keywords: xenotransplantation; genetic engineering; preclinical models; genetically modified donor organs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights and Treatments for Gynecological Cancers

edited by

Nicoletta D'Alessandris

submission deadline 30 Sep 2025 | Viewed by 57 | Submission Open

Keywords: gynecological cancers; cancers; endometrial cancers; cervical cancer; tumor microenvironment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bone and Cartilage Injury and Repair: Molecular Aspects

edited by Silvia María Díaz-Prado

submission deadline 30 Sep 2025 | Viewed by 57 | Submission Open

Keywords: bone and cartilage repair; regenerative medicine; inflammation and immune response; stem cell therapy; extracellular matrix remodeling; biomaterials; drug delivery systems; therapeutic targets; biomarkers

(This special issue belongs to the Section Molecular Biology)

Emerging Viral Epidemics

edited by Nikolaos Siafakas

submission deadline 30 Sep 2025 | Viewed by 56 | Submission Open

Keywords: emerging viruses; diagnostic virology; viral epidemiology; viral evolution; zoonotic infections; public health; surveillance

(This special issue belongs to the Section Molecular Microbiology)

Emerging Biomaterials for Cartilage Regeneration

edited by

Valentina Vassallo

submission deadline 30 Sep 2025 | Viewed by 56 | Submission Open

Keywords: osteoarthritis; glycosaminoglycans; biomaterials; cartilage regeneration; mesenchymal cells; chondrocytes

(This special issue belongs to the Section Biochemistry)

Study on the Microenvironment in Lymphoma

edited by

Jonathan P. Butchar

submission deadline 30 Sep 2025 | Viewed by 55 | Submission Open

Keywords: tumor microenvironment; lymphoma; hodgkin lymphoma; non-hodgkin lymphoma; burkitt lymphoma; follicular lymphoma; waldenströ m’ s macroglobulinemia; NK/T-cell lymphoma; diffuse large B-cell lymphoma; mantle cell lymphoma; marginal zone lymphoma; lymphoproliferative disorder; anaplastic large cell lymphoma; mediastinal B cell lymphoma; T-cell lymphomas

(This special issue belongs to the Section Molecular Oncology)

Hemolytic Anemia: From Molecular Mechanisms to Therapeutic Exploitation

edited by Joan-Lluis Vives-Corrons

submission deadline 30 Sep 2025 | Viewed by 54 | Submission Open

Keywords: hemolytic anemias; red blood cells; sickle cell disease; targeted therapies; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The New Developments in Third-Generation Sequencing Methods in Human Rare Diseases

edited by

Rick Kamps

submission deadline 30 Sep 2025 | Viewed by 54 | Submission Open

Keywords: short-read sequencing; long-read sequencing; single-cell rna sequencing; spatial-transcriptomic sequencing; single-nucleotide sequencing; structural-variant sequencing; protein-omics sequencing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Research in Obesity and Obesity Related Disorders: 3rd Edition

edited by

Grażyna Nowicka

submission deadline 30 Sep 2025 | Viewed by 54 | Submission Open

Keywords: biochemistry and molecular medicine; molecular and cellular mechanisms of disease pathogenesis; pathogenesis of metabolic disorders; the role of interaction between genetic and environmental factors in the pathogenesis of non-communicable diseases; atherosclerosis; obesity; obesity-related metabolic diseases and cancers

(This special issue belongs to the Section Molecular Biology)

Advances in Biological Breeding and Molecular Biology of Tropical Crops

edited by Yongzan Wei

submission deadline 30 Sep 2025 | Viewed by 54 | Submission Open

Keywords: tropical crops; biological breeding; tropical fruit; molecular biology; gene editing; transcrip-tional regulation; genomics

(This special issue belongs to the Section Molecular Plant Sciences)

Advances in Plant-Derived Nanomaterials: From Molecular Mechanisms to Biofortification

edited by

Ágnes Szepesi

submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open

Keywords: nanotechnology; green synthesis; sustainable nanomaterials; nano– bio interactions; crop production; plant-based solutions; bio-corona

(This special issue belongs to the Section Molecular Plant Sciences)

New Insights into Chemotherapeutic Agents in Cancer Treatment

edited by

Eleni Stamoula

submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open

Keywords: chemotherapy; molecular mechanisms; signal transduction; apoptosis; drug resistance; biomarkers; DNA damage; targeted therapy; cancer pathways; nanoparticles; nanomedicine; epigenetics

(This special issue belongs to the Section Molecular Pharmacology)

Drug-Induced Toxicity and Its Role in Disease Progression and Therapeutic Outcomes

edited by

Eugenia Gallardo

and

Tiago Rosado

submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open

Keywords: drug-induced toxicity; drug-drug interactions; drug delivery systems; toxicity; disease

(This special issue belongs to the Section Molecular Toxicology)

Molecular Application of Biomaterial in Skin Diseases

edited by

Danuta Nowicka

submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open

Keywords: chronic dermatoses; autologus material; PRP; stem cells; growth factors

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms of Antiviral Agents and Antiviral Therapy

edited by

Jesus Alberto Silvas

submission deadline 30 Sep 2025 | Viewed by 53 | Submission Open

Keywords: therapeutics; high-throughput screening; viral reverse genetics; luciferase; fluorescent; compound; repurpose; antiviral; diagnostics

(This special issue belongs to the Section Molecular Immunology)

Magnetic Nanoparticles: From Synthesis and Modification to Biomedical Applications

edited by

Ahmet Kertmen

submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open

Keywords: magnetite nanoparticles; colloidal interactions; X-ray characterizations; biomedical applications; method development; imaging

(This special issue belongs to the Section Molecular Nanoscience)

Recent Molecular Research in Colitis

edited by

Pablo García-Miranda

and

María Vázquez-Carretero

submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open

Keywords: colitis; inflammatory bowel disease (IBD); gut-brain axis; intestinal barrier; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Bioactive Peptides: Function, Metabolism and Synthesis

edited by

Leandro Mantovani de Castro

submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open

Keywords: bioactive peptides; antimicrobial peptides; antitumoral peptides; neurodegenerative diseases; metabolic diseases; chemical synthesis; cellular proteolysis; mass spectrometry; peptidomics; intracellular peptides; micropeptides

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research in Triple-Negative Breast Cancer: 2nd Edition

edited by

Yong-Moon Lee

submission deadline 30 Sep 2025 | Viewed by 52 | Submission Open

Keywords: triple negative breast cancer; lymph node metastasis; PMP22; prediction model using deep learning

(This special issue belongs to the Section Molecular Oncology)

Role of Mutations and Polymorphisms in Various Diseases: 2nd Edition

edited by

Anna Cieslinska

submission deadline 30 Sep 2025 | Viewed by 51 | Submission Open

Keywords: nutrigenomics; polymorphism; SNPs; mutations; predisposition; correlation; diversity; deletion; insertion

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research and Immune Landscape of Breast Cancer

edited by

Robson Monteiro

submission deadline 30 Sep 2025 | Viewed by 50 | Submission Open

Keywords: breast cancer; immune landscape; single-cell analysis; omics; therapy resistance; metastasis

(This special issue belongs to the Section Molecular Immunology)

Collagen and Its Derivatives in Tissue Engineering

edited by

István Hornyák

submission deadline 30 Sep 2025 | Viewed by 49 | Submission Open

Keywords: collagen derivatives; tissue engineering; in vitro experiments; in vivo investigations; material degradation

(This special issue belongs to the Section Biochemistry)

Inflammatory Bowel Disease: Molecular Insights—2nd Edition

edited by

Belal Chami

submission deadline 30 Sep 2025 | Viewed by 49 | Submission Open

Keywords: genomic sequencing; microbiome; dysbiosis; commensal flora; omics; immunobiology; colitis; Crohn’ s disease; ulcerative colitis; multiomics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Influence of Genetics on Lymphatic System Diseases

edited by

Tomomi Watanabe-Asaka

submission deadline 30 Sep 2025 | Viewed by 49 | Submission Open

Keywords: lymphatic system; gene expression; disease model; medical application; lymphatic development; lymphatic function

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular and Clinical Advances in Ophthalmic Inflammation, Infection, and Degeneration

edited by Hyun Jin Shin

submission deadline 30 Sep 2025 | Viewed by 49 | Submission Open

Keywords: ophthalmic inflammation; ocular infection; ocular degeneration; molecular mechanisms; translational research

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Statin Induced Neurotoxicity

edited by

Iain P. Hargreaves

and

Adam P. Lightfoot

submission deadline 30 Sep 2025 | Viewed by 48 | Submission Open

Keywords: mitochondrial dysfunction; oxidative stress; coenzyme Q10; simvastatin; neurotoxicity; blood brain barrier

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanism and Breeding of Abiotic and Biotic Stress Tolerance in Crops

edited by

Waltram Ravelombola

submission deadline 30 Sep 2025 | Viewed by 48 | Submission Open

Keywords: crop production; abiotic stress; biotic stress; genetic mechanism; molecular markers; crop variety improvement

(This special issue belongs to the Section Molecular Plant Sciences)

Machine Learning Applications in Bioinformatics and Biomedicine: 3rd Edition

edited by Hao Lv

submission deadline 30 Sep 2025 | Viewed by 47 | Submission Open

Keywords: genome; transcriptome; proteome; metabolome; drug target; machine learning; prediction of drug side effects; epigenetic marker discovery for diseases; molecular network marker; early screening of diseases

(This special issue belongs to the Section Molecular Informatics)

New Insights in the Mechanism of Obstetrical Complications: Prevention, Diagnosis, Monitoring, Treatment

edited by

Lucia Maria Procopciuc

and

Roxana Liana Lucaciu

submission deadline 30 Sep 2025 | Viewed by 47 | Submission Open

Keywords: high blood pressure; gestational diabetes; infections; preeclampsia; eclampsia; preterm labor; depresion; anxiety; pregnancy loss/miscarriage; stillbirth; premature membrane rupture; vaginal bleeding; placenta previa; anemia; intrauterine growth restriction; maternal risk factors; fetal risk factors; endothelial dysfunction; angiogenesis; oxidative stress; hormonal modifications; dyslipidemia; biochemical; genetic; epigenetic determinations; computational analysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights into Rare Diseases: From Pathogenesis to Innovative Therapies

edited by Grażyna Gromadzka

submission deadline 30 Sep 2025 | Viewed by 47 | Submission Open

Keywords: rare diseases; orphan disorders; orphan drugs; gene therapy; precision medicine; biomarkers in rare diseases; gene therapy; CRISPR therapy; CRISPR-mediated DNA editing; CRISPR technology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Therapies, Pathogenetic and Inflammatory Mechanisms in Thrombosis

edited by

Matteo Becatti

submission deadline 30 Sep 2025 | Viewed by 46 | Submission Open

Keywords: thromboinflammation; endothelial dysfunction; antithrombotic therapies; oxidative stress; thrombosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Latest Molecular Advances in Prostate Cancer

edited by Rejane Maira Góes

submission deadline 30 Sep 2025 | Viewed by 46 | Submission Open

Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy

(This special issue belongs to the Section Molecular Oncology)

New Molecular Insights into Antibacterial Material

edited by Rahela Carpa

submission deadline 30 Sep 2025 | Viewed by 46 | Submission Open

Keywords: antimicrobial resistance; nanoparticles; biopolymers; antimicrobial peptides; antimicrobial materials

(This special issue belongs to the Section Materials Science)

Exploring Therapeutic Targets in the Evolving Landscape of Cancer Immunotherapy 2nd Edition

edited by

Domenico Galati

submission deadline 30 Sep 2025 | Viewed by 46 | Submission Open

Keywords: immune checkpoints; targeted therapies; tumor microenvironment; cancer immunology; precision medicine; cell-based cancer therapy

(This special issue belongs to the Section Molecular Immunology)

Regulatory Mechanisms in Kidney Development and Function

edited by Gary F. Gerlach

submission deadline 30 Sep 2025 | Viewed by 45 | Submission Open

Keywords: drosophila nephrocyte; zebrafish pronephros; mesonephros; murine nephrogenesis; slit diaphragm; podocytes; junctions; tubule; mesenchymal-to-epithelia transition (MET); epithelial-to-mesenchymal transition (EMT); tubule segmentation; transcription factors; signaling pathways; foot processes; cytoskeleton; brush boarder; intercalated cells; renin angiotensin; diabetic kidney disease; podocytopathies; FSGS; minimal change disease; IgAN

(This special issue belongs to the Section Molecular Biology)

Molecular Biology of Periodontal Disease and Periodontal Pathogens

edited by Yago Leira and

João Botelho

submission deadline 30 Sep 2025 | Viewed by 45 | Submission Open

Keywords: periodontitis; general medicine; inflammation; bacteraemia; education

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lung Cancer: From Molecular Mechanisms to Novel Therapeutics: 2nd Edition

edited by

Mariacarmela Santarpia

and

Giulia Pasello

submission deadline 30 Sep 2025 | Viewed by 45 | Submission Open

Keywords: lung cancer; oncogene; targeted therapy; immunotherapy; predictive biomarkers; liquid biopsy

(This special issue belongs to the Section Molecular Oncology)

Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment—2nd Edition

edited by

Morris Karmazyn

submission deadline 30 Sep 2025 | Viewed by 45 | Submission Open

Keywords: cardiac hypertrophy; myocardial remodelling; heart failure; cellular mechanisms; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanomedicine: Application of Nanostructured Biomaterials in the Biomedical Field

edited by

Yaser Dahman

submission deadline 30 Sep 2025 | Viewed by 44 | Submission Open

Keywords: nanomedicine; nanostructured biomaterials; targeted drug delivery; tissue regeneration; biosensing

(This special issue belongs to the Section Molecular Nanoscience)

Relationship Between Plant Microbiome and Immunity

edited by

Sergio Molinari

submission deadline 30 Sep 2025 | Viewed by 43 | Submission Open

Keywords: microbiome; plant immune system; rhizosphere of plant roots; microbe-associated molecular patterns (MAMPs)

(This special issue belongs to the Section Molecular Plant Sciences)

Dialogue Between Inflammation and Immunity: From Mechanism to Therapy

edited by

Nikolina Mihaylova

submission deadline 30 Sep 2025 | Viewed by 43 | Submission Open

Keywords: inflammation; immune activation; immunomodulation; tolerance; immunotherapy; autoimmune diseases; cancer

(This special issue belongs to the Section Molecular Immunology)

Roles of Non-Coding RNAs in Cancer

edited by Amit K. Mitra

submission deadline 30 Sep 2025 | Viewed by 43 | Submission Open

Keywords: lncRNA; miRNA; cancer; genomics; targeted therapy; biomarkers; drug resistance

(This special issue belongs to the Section Molecular Genetics and Genomics)

Bioactive Compounds in Bee Products: Chemistry, Mechanisms of Action and Nutritional Applications

edited by

Jarosław Widelski

and

Ioanna Chinou

submission deadline 30 Sep 2025 | Viewed by 43 | Submission Open

Keywords: honey; propolis; royal jelly; polyphenols; nutritional properties; bioactivity; analytical and isolation methods; bee pollen

(This special issue belongs to the Section Bioactives and Nutraceuticals)

The Role of Micronutrients in Cancer Prevention

edited by Jacek Baj

submission deadline 30 Sep 2025 | Viewed by 42 | Submission Open

Keywords: micronutrient; metallomics; metallomic analysis; nutrient; ICP-MS; ICP-OES; prevention; carcinogenesis

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research and Insights into COVID-19: Third Edition

edited by

Manuela Rizzi

and

Pier Paolo Sainaghi

submission deadline 30 Sep 2025 | Viewed by 42 | Submission Open

Keywords: SARS-CoV-2; COVID-19; prognostic and diagnostic biomarkers; molecular mechanism of infection; molecular pathophysiology; immune response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Pharmacology and Interventions in Cardiovascular Disease: 2nd Edition

edited by

Magdalena Zabielska-Kaczorowska

submission deadline 30 Sep 2025 | Viewed by 42 | Submission Open

Keywords: cardiovascular pharmacology; cardiovascular interventions; cardioprotection; myocardial ischemia and infarction; heart failure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Displaying special issue 2501-2550 on page 51 of 70.

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