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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Food Processing Industry’s 200th Anniversary: Bioactive Compounds, Antioxidants, and Potential Health Benefits (2nd Edition)

edited by

Vassilis Athanasiadis

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1856 | Submission Open

Keywords: antioxidants; bioactive compounds; food processing; functional foods; green processes; health potentials; molecular mechanisms; polyphenols; shelf life; vitamins

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Drug Repurposing in Rare Diseases: From Molecular Insights to Patient Benefits

edited by Claudia Fuchs

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1812 | Submission Open

Keywords: rare diseases/rare genetic diseases; drug repurposing/repositioning; molecular insights; shared molecular pathways; preclinical trials; case studies

(This special issue belongs to the Section Molecular Pharmacology)

New Advances in Erythrocyte Biology and Functions

edited by

Francesco Misiti

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1707 | Submission Open

Keywords: erythrocyte; red blood cells; red blood functions; vascular function; blood bank storage

(This special issue belongs to the Section Molecular Biology)

Molecular Insight into Bone Diseases

edited by Gaia Palmini

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1162 | Submission Open

Keywords: mineralization; bone diseases; rare bone diseases; non-coding RNAs; fibrous bone dysplasia; tumoral calcinosis; osteosarcoma; Ewing sarcoma; osteoporosis; Gorham-Stout disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Innovative Approaches for Investigations on Protein Interactions

edited by

Fabrizio Dal Piaz

Francesca Mensitieri

and

Maria Laura Bellone

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1155 | Submission Open

Keywords: protein– protein and protein– ligand interactions; proteomics; innovative approaches; LC-MS/MS; immunometric techniques; interactome; drug discovery and development

(This special issue belongs to the Section Biochemistry)

Association Between Oxidative Stress and Metabolic Diseases

edited by

Andrea Silvestrini

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1073 | Submission Open

Keywords: metabolic disease; oxidative stress; low-grade inflammation; antioxidant; endocrine disease; radical species

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Hypoxia: Molecular Mechanism and Health Effects

edited by

Pinar Uysal-Onganer

submission deadline 30 Sep 2025 | Viewed by 844 | Submission Open

Keywords: hypoxia; inflammation; oxidative stress; metabolic conditions; hypoxia-inducible factors (HIFs); oxidative stress; mitochondrial dysfunction; angiogenesis; metabolic reprogramming; apoptosis

(This special issue belongs to the Section Molecular Biology)

MicroRNAs as Biomarkers and Therapeutic Targets in Human Diseases

edited by Elena V. Bichenkova

submission deadline 30 Sep 2025 | 2 articles | Viewed by 826 | Submission Open

Keywords: microRNA biomarkers; diagnostic profiling; expression patterns; miRNA therapeutics; antimiRs; miRNA mimics; hybridisation; sequence-specificity; miRNA knockdown

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Research Advances in Retinal Neurodegeneration and Neuroprotection Strategies

edited by

Maccarone Rita

and

Darin Zerti

submission deadline 30 Sep 2025 | Viewed by 768 | Submission Open

Keywords: retinal neurodegeneration; retinal neuroprotection; retinal pigment epithelium dysfunction; electrophysiology; molecular targets; drug delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Trends in Redox Physiology Research

edited by Fotios Tekos

submission deadline 30 Sep 2025 | Viewed by 518 | Submission Open

Keywords: redox biology; oxidative stress; antioxidant mechanisms; redox signaling; cellular homeostasis; inflammation and redox; nutritional redox modulation; environmental toxicology and redox; mitochondrial dysfunction; oxidative stress biomarkers

(This special issue belongs to the Section Biochemistry)

The Role of Natural Products in Treating Human Diseases

edited by Luís R. Silva

submission deadline 30 Sep 2025 | Viewed by 510 | Submission Open

Keywords: natural products; phytochemicals; biological potential; pharmacological activity; health promoters; chronic diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Osteoblast Differentiation in Human Health and Disease

edited by Younho Han

submission deadline 30 Sep 2025 | 1 articles | Viewed by 500 | Submission Open

Keywords: osteoblast differentiation; bone remodeling; mesenchymal stem cells; skeletal diseases; osteogenesis; bone mineralization; osteoporosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Optical Materials: Molecular Advances of Their Synthesis, Properties and Medical Applications

edited by

Elżbieta Tomaszewicz

submission deadline 30 Sep 2025 | Viewed by 471 | Submission Open

Keywords: optical materials; luminescence; luminescence thermometry; laser materials; phosphors; biocompatible optical materials; optical imaging; fluorescent nanoparticles; rare-earth ion-doped nanomaterials; hard and soft tissue engineering; laser imaging systems

(This special issue belongs to the Section Materials Science)

Bioactive Compound Delivery Systems and Microbiome Interactions

edited by

Ramona Suharoschi

Adriana Fodor

and

Oana Lelia Pop

submission deadline 30 Sep 2025 | Viewed by 391 | Submission Open

Keywords: bioactive compounds; delivery systems; gut microbiome; personalized nutrition; bioavailability; encapsulation technologies; microbiome– bioactive interactions; targeted delivery; precision nutrition; synergistic interactions

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanism of VCP/p97 in Health and Diseases

edited by

Isabelle Rouiller

submission deadline 30 Sep 2025 | Viewed by 377 | Submission Open

Keywords: AAA ATPase; VCP/p97/cdc48/TER ATPase; AAA ATPase; protein unfolding; protein degradation; protein quality control; ERAD; mitochondria-associated degradation; lysosome degradation; ribosome-associated degradation; membrane fusion and trafficking; ubiquitin; TDP43; inclusion body myopathy (IBM); paget disease (PD); frontotemporal dementia (FD); MSP1; amyotrophic lateral sclerosis (ALS); charcot-marie-tooth disease 2Y; Parkinson’ s disease; intellectual development disabilities (IDDs); lysosomal diseases; tauopathies

(This special issue belongs to the Section Molecular Biology)

X-Linked Disorders: Epigenetic and Environmental Modulation of Phenotypes

edited by Yoram Chaiter and

Yossy Machluf

submission deadline 30 Sep 2025 | Viewed by 332 | Submission Open

Keywords: X-linked disorders; epigenetics; environmental factors; gene expression; clinical manifestations

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Insights into the Precision Medicine on Neoplastic Diseases: Challenges, Perspectives and Opportunities

edited by

Manuela Montanaro

submission deadline 30 Sep 2025 | Viewed by 324 | Submission Open

Keywords: cancer; molecular biology; precision medicine; targeted therapy

(This special issue belongs to the Section Molecular Oncology)

New Advances in Platelet Biology and Functions: 3rd Edition

edited by

Isabella Russo

submission deadline 30 Sep 2025 | 1 articles | Viewed by 296 | Submission Open

Keywords: platelet microparticles; thrombosis; inflammation; oxidative stress; antiplatelet drug; signal transduction; immunity; tumor growth

(This special issue belongs to the Section Molecular Biology)

Natural Active Substances in Human Diseases

edited by

Hyeung-Jin Jang

submission deadline 30 Sep 2025 | 1 articles | Viewed by 288 | Submission Open

Keywords: natural active substances; bioactive compounds; molecular mechanisms; traditional medicine; metabolic disorders; inflammatory diseases; neurodegenerative diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Mechanisms of Various Diseases and Drugs Involved in Vascular Tone Regulation in Cardiovascular Disease

edited by

Ju-Tae Sohn

submission deadline 30 Sep 2025 | 1 articles | Viewed by 287 | Submission Open

Keywords: vasoconstriction; vasodilation; calcium; protein kinase C; Rho-kinase; hypertension; nitric oxide

(This special issue belongs to the Section Molecular Biology)

Lipid Emulsion and Other Treatment in Drug Toxicity

edited by

Ju-Tae Sohn

submission deadline 30 Sep 2025 | Viewed by 277 | Submission Open

Keywords: lipid emulsions; toxicity; toxic drug; anesthetic drug

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Insights into Hepatocellular Carcinoma: From Carcinogenesis to Liver Transplantation

edited by

Kevin Tak-Pan Ng

submission deadline 30 Sep 2025 | 1 articles | Viewed by 262 | Submission Open

Keywords: hepatocarcinogenesis; molecular pathogenesis; tumor microenvironment; metabolic dysfunction-associated fatty liver disease (MAFLD); metastasis; genetic and epigenetic alterations; biomarkers; precision oncology; targeted therapy; immunotherapy; therapy resistance; immune escape; tumor recurrence; transplant oncology

(This special issue belongs to the Section Molecular Oncology)

Advances in Tumor Necrosis Factor and Inflammatory Diseases

edited by Salah Amasheh

submission deadline 30 Sep 2025 | Viewed by 258 | Submission Open

Keywords: tumor necrosis factor; inflammatory chronic disease; experimental biomedicine; epithelium; pathophysiology; immunology; therapeutic stategies

(This special issue belongs to the Section Molecular Oncology)

Computational Studies of Ionic Liquids and Their Analogues

edited by

Iuliia Voroshylova

and Elisabete Ferreira

submission deadline 30 Sep 2025 | Viewed by 214 | Submission Open

Keywords: ionic liquids; deep eutectic solvents; molecular dynamics; density functional theory; COSMO-RC; machine learning; ab initio

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Pathophysiology of Dermatitis: Mechanisms and Therapeutic Perspectives

edited by

Natalia Karolina Galińska

submission deadline 30 Sep 2025 | Viewed by 150 | Submission Open

Keywords: immune-mediated skin diseases; molecular mechanism of dermatitis; new therapeutic substances and treatment techniques; dermatitis; skin diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advancements in Molecular Science, Material Analysis, and Surface Treatments: Paving the Way for Future Technological Innovations

edited by

Fadoua El-Hajjaji

submission deadline 30 Sep 2025 | Viewed by 137 | Submission Open

Keywords: materials; surface treatments; corrosion; nanomaterials; coatings; molecular interactions; deposition

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms and Functions of Extracellular Vesicles

edited by

Sigrun Lange

and Jameel M. Inal

submission deadline 30 Sep 2025 | Viewed by 136 | Submission Open

Keywords: extracellular vesicles; molecular mechanisms; biomarkers; liquid biopsy; cell-communication; cellular function; pathobiology; clinical

(This special issue belongs to the Section Molecular Biology)

The Regulation of Microorganisms on Human Endocrine and Metabolic Systems

edited by Thi Phuong Nam Bui and Valentina Tremaroli

submission deadline 30 Sep 2025 | Viewed by 134 | Submission Open

Keywords: human gut microbiome; endocrine signaling; metabolism; obesity; type 2 diabetes; cardiometabolic diseases

(This special issue belongs to the Section Molecular Microbiology)

Heat Shock Proteins (HSPs): Biological Functions and Mechanisms of Actions

edited by

Soumya Patnaik

and

Gregory Blatch

submission deadline 30 Sep 2025 | Viewed by 122 | Submission Open

Keywords: heat shock proteins; apoptosis; immune cell activation; stress responses; misfolded proteins; cellular chaperones; cell signaling

(This special issue belongs to the Section Biochemistry)

Advances in Laboratory Animal Research for Precision Medicine in Cardiovascular Diseases

edited by Conrado Calvo

submission deadline 30 Sep 2025 | Viewed by 118 | Submission Open

Keywords: cardiovascular disease; experimental models and research; arrhythmias and cardiac electrophysiology; molecular science and imaging techniques; myocardial ischemia and heart failure; cardiac fibrillation and sudden cardiac death; circulation and blood vessels; diabetes and metabolic disorders; experimental datasets for precision medicine; data-driven in silico approaches

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Applications of Polymers in Organic Functional Materials

edited by

Paola Manini

submission deadline 30 Sep 2025 | Viewed by 104 | Submission Open

Keywords: functional polymers; polymer synthesis; stimuli-responsive polymers; self-healing polymers; nanostructured polymers; polymer composites; smart materials; polymeric catalysts; polymers in (bio)electronics; polymers for sustainable processes

(This special issue belongs to the Section Macromolecules)

Future Challenges and Innovation in Gynecological Oncology

edited by

Alejandro Herreros-Pomares

submission deadline 30 Sep 2025 | Viewed by 82 | Submission Open

Keywords: gynecologic oncology; molecular biomarkers; personalized medicine; ovarian cancer; immunotherapy; tumor microenvironment; drug resistance; translational research

(This special issue belongs to the Section Molecular Oncology)

Natural Products for Neuroprotection and Neurodegeneration

edited by

Patrycja Kupnicka

submission deadline 30 Sep 2025 | Viewed by 80 | Submission Open

Keywords: natural products; bioactive compounds; neuroprotection; neurodegeneration

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Macroporous, Mesoporous, and Microporous Materials

edited by

Magdalena Laskowska

submission deadline 30 Sep 2025 | Viewed by 78 | Submission Open

Keywords: functional materials; nanomaterials; nanostructures; molecular systems; porous materials

(This special issue belongs to the Section Materials Science)

Advances in Microbial Genomics: Insights from Whole Genomes and Metagenomes

edited by

Marcos Quintela Baluja

submission deadline 30 Sep 2025 | Viewed by 78 | Submission Open

Keywords: microbial evolution; whole-genome sequencing; metagenomics; horizontal gene transfer; antimicrobial resistance; computational genomics

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Role of Protein Kinase in Health and Diseases

edited by

Manuela Loi

submission deadline 30 Sep 2025 | Viewed by 77 | Submission Open

Keywords: protein kinases; phosphorylation; cancer; neurological disorder; targeted therapies; metabolic diseases

(This special issue belongs to the Section Biochemistry)

Advancing Regenerative Medicine: Basic Research and Translation in Clinics

edited by

Dragan Primorac

submission deadline 30 Sep 2025 | Viewed by 75 | Submission Open

Keywords: regenerative medicine; stem cells; tissue engineering; exosomes; orthobiologics

(This special issue belongs to the Section Molecular Biology)

New Insights into Lactoferrin: 2nd Edition

edited by

Antimo Cutone

and

Giovanni Musci

submission deadline 30 Sep 2025 | Viewed by 74 | Submission Open

Keywords: lactoferrin; lactoferrin structure; lactoferrin functions; infection; inflammation; iron homeostasis; oxidative stress; lactoferrin bioavailability

(This special issue belongs to the Section Molecular Immunology)

Genetic Engineering for Stress Tolerance in Crops

edited by

Muhammad Waseem

submission deadline 30 Sep 2025 | Viewed by 73 | Submission Open

Keywords: genetic engineering; stress tolerance; crop improvement; drought resistance; salt tolerance; heat stress; CRISPR; RNAi; genetic modification; synthetic biology; pest resistance; crop transformation; abiotic stress; environmental resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Molecular Advances in Assisted Reproductive Technologies

edited by

Sung Tae Kim

submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open

Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology; morpho kinetics; in vitro gametogenesis; in vitro oocyte maturation; reproductive tissue cryopreservation; artificial intelligence (AI)

(This special issue belongs to the Section Molecular Biology)

Neurogenesis and Neurodegeneration: Insights into Regeneration and the Impact of Neurotrophins

edited by

Eva Terzibasi Tozzini

submission deadline 30 Sep 2025 | Viewed by 71 | Submission Open

Keywords: neurogenesis; neurodegeneration and regeneration; neurotrophins; brain plasticity

(This special issue belongs to the Section Molecular Neurobiology)

Psychobiotics as Next-Generation Probiotics: A Holistic Approach to Mental Health and Gut–Brain Axis Modulation

edited by

Edyta Juszczuk-Kubiak

submission deadline 30 Sep 2025 | Viewed by 70 | Submission Open

Keywords: probiotics; gut microbiota; gut– brain axis; mental health

(This special issue belongs to the Section Molecular Biology)

Foundational Studies Using Model Systems for Molecular Insights into Metabolism, Aging, and Disease

edited by

James T. Arnone

submission deadline 30 Sep 2025 | Viewed by 69 | Submission Open

Keywords: Saccharomyces cerevisiae and yeasts; Caenorhabditis elegans and nematodes; Arabidopsis thaliana and plants; Drosophila melanogaster; Mus musculus; established and emerging model systems

(This special issue belongs to the Section Molecular Biology)

Molecular-Scale Design, Synthesis, and Applications of (Photo)Electrochemical Materials for Sustainable Energy and Environmental Solutions

edited by

Shiwei Lin

and

Zhaohui Xiao

submission deadline 30 Sep 2025 | Viewed by 68 | Submission Open

Keywords: molecular-scale material engineering; photoelectrocatalysis/electrocatalysis; sustainable energy conversion; atomic-precision synthesis; environmental remediation technologies

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Algae-Derived Bioactives: Key Molecular Interactions Govern High-Value Applications

edited by Evan Stephens and Kirsten Heimann

submission deadline 30 Sep 2025 | Viewed by 67 | Submission Open

Keywords: microalgae; macroalgae; cyanobacteria; bioactive compounds; health and nutrition; algal food products; market analysis

(This special issue belongs to the Section Molecular Microbiology)

Recent Advances in New Biomarkers for Cancers

edited by

Maria Panagopoulou

submission deadline 30 Sep 2025 | Viewed by 65 | Submission Open

Keywords: biomarkers; cancer research; liquid biopsy; epigenetic and genetic biomarkers; precision oncology; diagnosis; prognosis; prediction

(This special issue belongs to the Section Molecular Oncology)

Biological Effects of Radiation on Human Cells and Tissues

edited by

Maria Paola Bertuccio

submission deadline 30 Sep 2025 | Viewed by 65 | Submission Open

Keywords: radiation exposure; molecular pathways; inflammation; immune response; biochemical markers; electromagnetic hypersensitivity

(This special issue belongs to the Section Molecular Biology)

Metallopharmaceuticals: Current Trends and Future Perspectives in Cancer Immunoediting

edited by

Marialuisa Piccolo

and

Claudia Riccardi

submission deadline 30 Sep 2025 | Viewed by 63 | Submission Open

Keywords: metal-based drugs; anticancer activity; mechanisms of action; tumor microenvironment; immune cell regulation; cancer immunity; metal– protein interactions; metal– nucleic acid interactions

(This special issue belongs to the Section Molecular Pharmacology)

Molecular Research in Airway Diseases

edited by

Giusy Daniela Albano

submission deadline 30 Sep 2025 | Viewed by 63 | Submission Open

Keywords: airway diseases; inflammation; immunopharmacology; cellular models; biomarkers; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Medicinal Plant Resources—from Molecular Studies to Sustainable Use

edited by Ekaterina Kozuharova

submission deadline 30 Sep 2025 | Viewed by 62 | Submission Open

Keywords: genetic improvement of medicinal plants; sustainable use; bioactive compounds

(This special issue belongs to the Section Molecular Plant Sciences)

Displaying special issue 2451-2500 on page 50 of 70.

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