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Molecular Insights and Treatments for Gynecological Cancers

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 35

Special Issue Editor


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Guest Editor
Unità di Ginecopatologia e Patologia Mammaria, Dipartimento Scienze della Salute della Donna, del Bambino e di Sanità Pubblica, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy
Interests: immunohistochemistry

Special Issue Information

Dear Colleagues,

Gynecological cancers, including ovarian, cervical, and endometrial cancers, present significant challenges in both diagnosis and treatment. Biochemistry and molecular biology play pivotal roles in understanding the molecular mechanisms underlying these cancers. Advances in genomic profiling, proteomics, and metabolomics have revealed key biomarkers for early detection, prognosis, and therapeutic targets. Specific mutations, such as those in BRCA1/2 genes, have enhanced personalized treatment strategies, particularly in ovarian cancer. Additionally, molecular signaling pathways, such as those involving PI3K/AKT and MAPK, are critical in cancer progression and resistance to therapies. Understanding the tumor microenvironment, including immune evasion mechanisms, may also open up promising avenues for immunotherapy. This Special Issue explores the intersection of biochemistry and molecular biology in gynecological cancers, emphasizing the development of novel diagnostic tools, therapeutic approaches, and the exploration of molecular markers. These advancements offer hope for improved patient outcomes through targeted precision medicine strategies.

Dr. Nicoletta D'Alessandris
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • gynecological cancers
  • cancers
  • endometrial cancers
  • cervical cancer
  • tumor microenvironment

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Published Papers

This special issue is now open for submission.
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