Emerging Biomaterials for Cartilage Regeneration
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 63
Special Issue Editor
Interests: mechanical and biochemical characterization of gels and/or biomaterials; isolation of primary human cells; diseases in vitro models; cellular differentiation toward a specific phenotype; biocompatibility; cells proliferation assay; wound healing assay; evaluation of specific genes and proteins expression; cytochines and chemokines secretion evaluation through multiplex assay; anti-inflammatory and anti-oxidant activity
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Even though there have been many advances in the field of regenerative medicine, currently, there is no definitive cure for osteoarthritic diseases. However, the use of medical devices based on glycosaminoglycans to treat osteoarthritis symptoms and attempt to delay surgery are increasingly widespread.
Implanting mesenchymal cells and chondrocytes with specifically functionalized scaffolds/biomaterials/gels/nanoparticles allows for the generation of a suitable environment for cartilage recovery. Furthermore, the in vitro pre-conditioning of cells may facilitate the local environment for tissue regeneration.
The aim of this Special Issue is to share with the scientific community useful results for the development and application of glycosaminoglycan (also chemically modified)-based materials/scaffolds/gels/sheets to improve cartilage regeneration. Another purpose is to shed light on the new biochemical mechanisms related to cartilage regeneration.
Original research articles and mini- and complete reviews are welcome.
Potential topics include, but are not limited to, the following:
- The design and preparation of scaffolds based on modified or unmodified glycosaminoglycans for the purpose of cartilage regeneration;
- The development of gels/scaffolds/biomaterials/sheets for implanting mesenchymal or articular cells;
- The regulation of anti-oxidant and anti-inflammatory effects;
- The development of methods to prepare cells for use in cartilage regeneration;
- New strategies for the functionalization of biomaterials;
- The development of medical devices based on glycosaminoglycans produced by biotechnological means with potential applications in the treatment of osteoarthritic diseases.
Dr. Valentina Vassallo
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- osteoarthritis
- glycosaminoglycans
- biomaterials
- cartilage regeneration
- mesenchymal cells
- chondrocytes
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
