Submit to IJMS Review for IJMS Propose a Special Issue

Journal Menu

Journal Browser

Special Issues

International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

Section

Search by Title/Keyword

Order results

Display

Results per page

Molecular Aspects of Diabetes and Its Complications

edited by

Giuseppe Murdolo

submission deadline 30 Nov 2025 | Viewed by 47 | Submission Open

Keywords: obesity; insulin resistance; type 2 diabetes; atherosclerosis; endothelial dysfunction; cardiovascular disease; peripheral artery disease; diabetic feet; diabetic micoangiopathy; diabetic neuropathy; regenerative medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Current Advance in Infectious and Inflammatory Diseases

edited by

Justyna Agier

and

Paulina Żelechowska

submission deadline 30 Nov 2025 | Viewed by 47 | Submission Open

Keywords: inflammatory diseases; infectious diseases; host– pathogen interactions; antimicrobial resistance; immune modulation; cytokine signaling

(This special issue belongs to the Section Molecular Microbiology)

Advances in Glyco-Based Anticancer Agents

edited by Pedro Colinas

submission deadline 30 Nov 2025 | Viewed by 46 | Submission Open

Keywords: carbohydrates; cancer; Warburg effect; glycolysis; enzyme inhibitors; transporters inhibitors; docking simulations; tumor microenvironment

(This special issue belongs to the Section Biochemistry)

Pathogenesis of Pulmonary Arterial Hypertension: Differences in Molecular Mechanisms Between Neonatal and Adult Pulmonary Hypertension

edited by Germán Ebensperger

submission deadline 30 Nov 2025 | Viewed by 46 | Submission Open

Keywords: pulmonary arterial hypertension; newborn; cardiovascular perinatal transition; vascular remodeling; vascular reactivity; vascular inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Precision Medicine for Cancer-Associated Thrombosis: The Role of Biomarkers

edited by Darko Antic

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: biomarkers; precision medicine; cancer-associated thrombosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advanced Research on Antioxidant Activity

edited by Agnieszka Filipek

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: antioxidants; advanced mechanisms of action; signaling pathways; molecular mechanism; biologically active compounds

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Studies of DNA Strand Exchange

edited by

Masayuki Takahashi

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: DNA strand exchange; homologous recombination: RecA-family recombinases; drug resistance: drug development against recombinases; evolution

(This special issue belongs to the Section Molecular Biophysics)

Molecular Insights into Mechanobiology of Regeneration

edited by

Christopher Robinson

and Timothy R. Deer

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: mechanotransduction; regeneration; stem cells; extracellular matrix; tissue repair

(This special issue belongs to the Section Molecular Biophysics)

Molecular Advances in Translational Infectious Diseases Research

edited by

Carlo Acierno

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: translational medicine; molecular pathogenesis; host– pathogen interaction; antimicrobial resistance; immune evasion; microbiome and infection; biomarkers; multi-omics approaches; infectious disease models; personalized infectious disease therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Glycobiology: The New Discoveries, Approaches, and Technical Developments: 2nd Edition

edited by Sanja Dabelić

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: glycans; lectins; glycoconjugates; glycosylation; genetic disorders of glycosylation; glycomics and glycoproteomics

(This special issue belongs to the Section Macromolecules)

Eukaryotic Cells Under Stress: Biochemical and Physiological Mechanisms of Resistance and Resilience

edited by

Bruno Hay Mele

and

Carmen Arena

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: cellular stress response; oxidative stress; bioactive compounds; ROS; DNA damage/repair; environmental stressors; molecular chaperones; antioxidant in human diseases

(This special issue belongs to the Section Molecular Biology)

Adhesion, Invasion, and Metastasis in Cancer Progression

edited by

Pinar Uysal-Onganer

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: cancer metastasis; cellular adhesion; invasion and migration; noncoding RNAs; EMT; Wnt/β -catenin signalling; tumour microenvironment; biomarkers; AI-driven metastasis prediction

(This special issue belongs to the Section Molecular Oncology)

Circulating Biomarkers for the Diagnosis of Cancer

edited by Fernando Luiz Affonso Fonseca

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: biomarkers; circulating ; lab methods; diagnosis; screening

(This special issue belongs to the Section Molecular Oncology)

Molecular Mechanisms and Therapeutic Targets in Cardiovascular Health and Cardiotoxicity

edited by

Rui Vitorino

submission deadline 30 Nov 2025 | Viewed by 45 | Submission Open

Keywords: cardiovascular; ischemia; heart failure; arrhythmogenesis; myocardial remodeling; endothelial dysfunction; cardiology; cardio-oncology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nanobiotechnology: Breaking Barriers in Phytomedicine

edited by

Maria Aparecida Medeiros Maciel

submission deadline 30 Nov 2025 | Viewed by 44 | Submission Open

Keywords: nanotechnology; nanobiotechnology; phytocompounds; phytochemistry; natural products

(This special issue belongs to the Section Molecular Nanoscience)

Non-Coding RNAs’ Functionality—Diagnosis and Therapy in Cancer and Other Indications (2nd Edition)

edited by

Mohamed Raafat El-Gewely

submission deadline 30 Nov 2025 | Viewed by 44 | Submission Open

Keywords: non-coding RNAs (ncRNAs); long non-coding RNAs (lncRNAs); MicroRNAs (miRNAs); circular RNAs (circRNAs); epigenetic and post-transcriptional regulation; epithelial– mesenchymal transition (EMT); cell proliferation and Apoptosis; biomarkers and Liquid biopsy; RNA-based therapeutics; next-generation sequencing (NGS); CRISPR/Cas9 screening; single-cell RNA sequencing (scRNA-seq); RNA interference (RNAi); cancer stem cells; early cancer diagnosis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Computational Cancer Genomics and Molecular Profile in Breast Cancer

edited by Daniel Guimarães Tiezzi and

Stefano Maria Pagnotta

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: breast cancer; computational biology; genomics; molecular biology

(This special issue belongs to the Section Molecular Informatics)

Cellular Memory in Response to Environmental Conditions

edited by

Satoshi Kishigami

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: cellular memory; cellular environment; embryonic development; epigenetics; transgenerational inheritance; mammals; DOHaD

(This special issue belongs to the Section Molecular Biology)

Contemporary Perspective of Cardio-Kidney Metabolic Syndrome: From Prevention to Management

edited by Alberto Palazzuoli,

Francesco Fedele

and

Anna Mattioli

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: cardiovascular risk factors; metabolic syndrome; chronic kidney disease; heart failure; endothelial dysfunction

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gene Regulation in Endocrine Disease, 2nd Edition

edited by

Alberto Falchetti

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: gene regulation; endocrine disease; endocrinology; diabetes mellitus; thyroid disorders

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Roles of Phytochemicals in Molecular Signaling Networks

edited by

Jui-Hung Yen

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: phytochemicals; molecular signaling pathways; inflammation; apoptosis; chronic diseases; cancer; cardiovascular diseases; structure– activity relationships

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Deciphering Allergies—Structural and Immunological Characterization of Allergenic Proteins and Immunomodulatory Agents: 2nd Edition

edited by

Marija Gavrović-Jankulović

submission deadline 30 Nov 2025 | Viewed by 43 | Submission Open

Keywords: allergen; allergenicity; IgE; innate immunity; exposome; cross-reactivity; B cell epitopes; T cell epitopes; in silico prediction

(This special issue belongs to the Section Molecular Immunology)

Omics Approach to Uncovering Signalling and Gene Regulation in Plants

edited by Xiang Li and Jingchun Shi

submission deadline 30 Nov 2025 | Viewed by 42 | Submission Open

Keywords: omics; plant signalling; gene regulation; bioinformatics

(This special issue belongs to the Section Molecular Plant Sciences)

Biometallic Nanoparticles: Synthesis, Functionalization and Multidisciplinary Applications

edited by

Elvira Rozhina

submission deadline 30 Nov 2025 | Viewed by 42 | Submission Open

Keywords: biogenic nanomaterials; antibacterial agents; plant extracts; biogenic silver nanoparticles; biofilms; cytotoxicity

(This special issue belongs to the Section Molecular Nanoscience)

Advanced Research in Alzheimer’s Disease: From Pathology to Therapy

edited by Sofía Yolanda Díaz Miranda

submission deadline 30 Nov 2025 | Viewed by 42 | Submission Open

Keywords: multifunctional compounds in Alzheimer’ s disease therapy; translational medicine in Alzheimer's disease; novel drug candidates for Alzheimer's disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Dermatology: Advances in Pathophysiology and Therapies (3rd Edition)

edited by

Montserrat Fernández-Guarino

submission deadline 30 Nov 2025 | Viewed by 42 | Submission Open

Keywords: immunodermatology; cutaneous lymphoma; cutaneous drug reaction; erythroderma; psoriasis; atopic dermatitis; eczematous reactions; cutaneous manifestation of systemic diseases; cutaneous vasculitis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neuroinflammation: Emerging Insights and Advances in Drug Development

edited by

Guya Diletta Marconi

Francesca Diomede

Jacopo Pizzicannella

and Paolo Gugliemi

submission deadline 30 Nov 2025 | Viewed by 42 | Submission Open

Keywords: neuroinflammation; drugs; neurodegenerative; Parkinson’ s disease; Alzheimer’ s disease; multiple scleroris; stroke

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Mechanisms and Therapeutic Targeting of Inflammatory Complications

edited by

Kota V. Ramana

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: inflammation; oxidative stress; cytokines; autoimmune diseases; infectious diseases; cancer; targeted therapies; molecular pathways; asthma; sepsis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in the Genetics and Precision Breeding of Tomato

edited by Younghoon Park

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: climate change; gene editing; genomic selection; flavor; functional compounds; molecular marker; omics; precision breeding; Solanum lycopersicum; tomato

(This special issue belongs to the Section Molecular Plant Sciences)

Protein–Protein Interactions in Human Cancer

edited by

Geng Wu

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: protein– protein interactions; protein– protein complexes; human cancer; signal transduction pathways; protein structure and function

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Pharmacological Insights on Natural Macromolecules and Natural Small Molecules: 2nd Edition

edited by

Dong-Sung Lee

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: bioactive natural molecules; natural macromolecules; natural small molecules; drug delivery; inflammatoty diseases; neurodegenerative diseases; skin diseases; cancer; metabolic diseases

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Stem Cell and Epigenetic Regulation in Regenerative Medicine

edited by

Giuseppe Garroni

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: mesenchymal stem cells; regenerative medicine; stemness genes; stem cell differentiation; molecular regulation; gene expression; cell– environment interactions; conditioned medium; secreted factors; epigenetic modification

(This special issue belongs to the Section Molecular Biology)

Interstitial Lung Diseases: From Molecular Pathology to New Treatments

edited by

Yasuhiko Koga

submission deadline 30 Nov 2025 | Viewed by 41 | Submission Open

Keywords: interstitial lung diseases (ILDs); therapeutic strategies; molecular pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Structural, Optical and Electrical Properties of Metal Complexes

edited by

Jana Pisk

and

Luka Pavic

submission deadline 30 Nov 2025 | Viewed by 40 | Submission Open

Keywords: metal complexes; transition metal (TM) complexes; TM-based materials; ligand field; electronic configuration; optical properties; density functional theory; time-dependent DFT; structure– property– function relationships

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Microglia in Neurological Disorders: Potential Therapeutic Targets and Underlying Mechanisms

edited by

Masashi Tanaka

submission deadline 30 Nov 2025 | Viewed by 40 | Submission Open

Keywords: cerebral amyloid angiopathy; Alzheimer's disease; amyloid-β fibril formation

(This special issue belongs to the Section Molecular Neurobiology)

New Advances in Metal Nanoparticles

edited by

Emilia Konował

submission deadline 30 Nov 2025 | Viewed by 40 | Submission Open

Keywords: metal nanoparticles; molecular-level mechanisms; functional nanostructures; environmental nanotechnology; nanoparticle stability; catalysis; hybrid nanomaterials; bimetallic systems; ligand– nanoparticle interactions

(This special issue belongs to the Section Molecular Nanoscience)

Molecular View of Natural Products with Antiviral Effects

edited by

Jin-ching Lee

submission deadline 30 Nov 2025 | Viewed by 40 | Submission Open

Keywords: virus; phytochemicals; nutritional supplements; marine extracts; antioxidants

(This special issue belongs to the Section Molecular Microbiology)

Research Progress on Photosensitizers and Photodynamic Therapy

edited by

Michal Heger

submission deadline 30 Nov 2025 | Viewed by 40 | Submission Open

Keywords: photodynamic therapy; photosensitizers; tumor microenvironment; nanotechnology; immunotherapy; targeted drug delivery; reactive oxygen species; hypoxia; combination therapy; molecular mechanisms

(This special issue belongs to the Section Biochemistry)

Natural Antioxidants—Sources, Characteristics, and Biological Activity

edited by

Maciej Spiegel

submission deadline 30 Nov 2025 | Viewed by 39 | Submission Open

Keywords: natural antioxidants; oxidative stress; reactive oxygen species; inflammation; free radicals; structure– activity relationship; nutraceuticals; synergistic effects; plant-derived compounds; drug discovery

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Artificial Intelligence and Data Science for the Discovery of Anticancer Targets and Decision Support

edited by

Soumia Ziti

submission deadline 30 Nov 2025 | Viewed by 39 | Submission Open

Keywords: artificial intelligence in oncology; data science and decision support in cancer therapy; target discovery and biomarker identification; machine learning and multi-omics integration; predictive modeling in precision medicine

(This special issue belongs to the Section Molecular Informatics)

Bioactive Small Molecules in Tissue Repair and Regeneration

edited by

Ildiko Bock-Marquette

submission deadline 30 Nov 2025 | Viewed by 38 | Submission Open

Keywords: small molecules; organ and tissue regeneration; development; aging

(This special issue belongs to the Section Molecular Biology)

Plant Metabolites under Environmental Stress: Mechanisms, Responses and Adaptation Strategies

edited by

Alfosea-Simón Marina

submission deadline 30 Nov 2025 | Viewed by 38 | Submission Open

Keywords: omics; biosynthesis; defense; stress; adaptation; metabolites

(This special issue belongs to the Section Molecular Plant Sciences)

Novel Cell Signaling Targets and Mechanism for Effective Individualized Therapies

edited by Kazuyuki Matsushita

submission deadline 30 Nov 2025 | Viewed by 38 | Submission Open

Keywords: novel cell signaling targets; individualized therapies; addiction signal pathway; diagnosis and treatment; cancer; neurodegenerative diseases; cell development

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Modeling: Latest Advances and Applications, 2nd Edition

edited by

Maria Alexandra Mernea

and

Dan Florin Mihǎilescu

submission deadline 30 Nov 2025 | Viewed by 38 | Submission Open

Keywords: molecular modeling; computational chemistry; drug design; material science; biomolecular interactions; algorithmic advances; theoretical chemistry; simulation techniques; predictive modeling; interdisciplinary applications

(This special issue belongs to the Section Molecular Biophysics)

Kidney Diseases: Molecular Research and Novel Therapies

edited by Niels Olsen Saraiva Camara

submission deadline 30 Nov 2025 | Viewed by 38 | Submission Open

Keywords: kidney disease; immunology and inflammation; zebrafish models; therapeutic targets; modern-era drivers of renal pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Antimicrobial Nanoparticles: Mechanisms, Applications, and Future Directions

edited by

Carmen Curutiu

and

Alina Maria Holban

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: antimicrobial activity; nanoparticles; biofilm nano-modulators; antibiotic resistence; wastewater treatment; preservative properties of nanoparticles

(This special issue belongs to the Section Molecular Microbiology)

Natural Product-Inspired Anticancer Drug Development

edited by

Erzsébet Mernyák

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: anticancer; antiproliferative; cytotoxic; natural product; drug development; semi-synthesis; total synthesis; structure– activity relationship; computational simulation; enzyme inhibition

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Updates and Advances in the Field of Glioblastomas: Mechanisms, Microenvironment and Treatments

edited by

Samantha Epistolio

submission deadline 30 Nov 2025 | Viewed by 37 | Submission Open

Keywords: GBM; molecular classification; pediatric diffuse gliomas; signaling pathways in GBMs; recurrent gliomas; midbrain gliomas; immunotherapy; targeted therapies for GBMs

(This special issue belongs to the Section Molecular Oncology)

Antibacterial Nanomaterials for Medicinal Applications

edited by