Intercellular Adhesion and Inflammatory Response in Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 57
Special Issue Editor
Interests: adhesion molecules; intercellular communication; epithelial–mesenchymal transition; cancer; metastasis; gastrointestinal cancer; pancreatic cancer; inflammatory bowel diseases
Special Issue Information
Dear Colleagues,
Adhesion is a remarkable process that holds cells in orderly groups to form tissues. It also allows for interactions between cells and with the extracellular matrix. However, adhesion abnormalities play a key role in the inflammatory processes associated with cancer. Disturbances in adhesion mechanisms can affect interactions between inflammatory cells, vascular endothelial cells, and cancer cells. Adhesive proteins enable the migration of inflammatory cells to the site of tumor development, where they can modulate the immune response, affect the tumor microenvironment, and inhibit cancer cell proliferation. On the other hand, abnormalities in cancer cell adhesion can lead to evasion of the immune response, promoting migration and invasion. Therefore, it is extremely important to understand the role of adhesion processes in the inflammatory response in cancer due to the possibility of developing new therapeutic strategies in cancer treatment.
The aim of this Special Issue is to publish the latest basic and clinical research on the role of intercellular adhesion in the context of the inflammatory response in the neoplastic process.
Dr. Anna Pryczynicz
Guest Editor
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Keywords
- adhesion
- cancer
- cancer therapy
- inflammation
- microenvironment
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