New Insights into Adipose Tissue Metabolic Function and Dysfunction, 4th Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 September 2025 | Viewed by 511
Special Issue Editor
Interests: pharmacology; natural products; oxidative stress; inflammatory disease; atherosclerosis; metabolic disease; neurodegenerative diseases; autophagy; proliferation and differentiation process
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Adipose tissue is widely known as an endocrine organ that can modulate systemic metabolism due to its effects on energy storage, adipokine production, and adaptive thermogenesis. This endocrine function is carried out in various organs, such as the liver, kidney, pancreas, and brain, thus contributing to homeostatic regulation, energy balance, insulin sensitivity, and vascular–endothelial function.
The dysregulation of adipocyte differentiation, metabolism, and endocrine functions leads to adipose tissue dysfunction, which triggers the activation of molecular pathways involved in the physiopathology of overall metabolic diseases, such as obesity, inflammation, insulin resistance, and type 2 diabetes.
New therapeutic approaches targeting adipose tissue and its signaling molecules and heterogeneity could provide potential advances in understanding its pathophysiology and in treating several metabolic syndromes.
This Special Issue of the International Journal of Molecular Sciences, entitled “New Insights into Adipose Tissue Metabolic Function and Dysfunction”, aims to compile original research papers and/or relevant updates within the literature on new insights into the pathogenesis, molecular pathways, and beneficial effects of novel and safe treatments for metabolic diseases associated with adipose tissue dysfunction. In Volumes I, II, and III, we published more than 30 manuscripts that attracted a high readership and number of citations. We welcome you to read these to inspire your own research contributions (comprehensive review, original article, etc.) to Volume IV.
Dr. Federica Mannino
Guest Editor
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Keywords
- inflammation
- browning
- thermogenesis
- adipogenesis
- diabetes
- adipokines
- energy storage
- insulin resistance
- obesity
- lipolysis
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