Radiation-Induced DNA Damage and Toxicity
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".
Deadline for manuscript submissions: 30 October 2025 | Viewed by 2171
Special Issue Editors
Interests: radiation; DNA damage; skin cancer (melanoma and non-melanoma); immunosuppression
Special Issues, Collections and Topics in MDPI journals
Interests: materials for radiation shielding and protection; optical materials for biomedical applications; nanostructured materials for biomedical applications; radiation dosimetry and assessment biophotonics; optics and photonics; non-ionizing radiation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Radiation-induced DNA damage and toxicity is a critical area of study that explores how ionizing radiation interacts with biological systems, leading to cellular and molecular damage, particularly at the DNA level. When exposed to radiation, cells can experience direct DNA damage, such as double-strand breaks, or indirect damage through the generation of reactive oxygen species (ROS). This damage can lead to mutations, chromosomal aberrations, and carcinogenesis if not properly repaired.
Radiation-induced toxicity also extends to tissues and organs, contributing to both acute and long-term health effects, such as radiation sickness, increased cancer risk, and tissue necrosis. Understanding the mechanisms of DNA repair, the influence of dose and dose rate, and the role of individual susceptibility is crucial for developing protective strategies and therapies.
This topic is increasingly relevant in medical, environmental, and occupational settings, where radiation exposure is a concern. It also has implications for cancer treatment, where balancing the therapeutic benefits of radiation against its potential to cause DNA damage in healthy tissues is a constant challenge.
This Special Issue will gather cutting-edge research on the molecular mechanisms of radiation-induced DNA damage, advancements in DNA repair strategies, the development of biomarkers for radiation exposure, and novel therapeutic strategies to mitigate toxicity, and will help in understanding the implications of radiation for public health and safety.
In this Special Issue, original research articles, brief reports, reviews, and interviews are welcome. The research areas may include all aspects of ionizing and non-ionizing radiation-induced DNA damage, ionizing and non-ionizing radiation's effects on cancer, and ionizing and non-ionizing radiation on the immune system, among other relevant topics.
We look forward to receiving your contributions.
Dr. Mohammad Asif Sherwani
Prof. Dr. Muhammad Maqbool
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- radiation
- DNA damage
- toxicity
- immune response
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.