Multi-Omics Approaches to Disentangle Pathomechanisms in Neurological Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 October 2025 | Viewed by 544
Special Issue Editors
Interests: neurodegeneration; neurobiology; molecular mechanisms; lysosomal storage diseases; in vitro disease models; omics; bioinformatics
Interests: omics; bioinformatics; neurosciences; in vitro disease models; biomarker discovery; bioenergetics; mitochondrial disorders
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Special Issue Information
Dear Colleagues,
We are pleased to invite you to participate in our Special Issue on “Multi-omics Approaches to Disentangle Pathomechanisms in Neurological Disease”, which is being prepared for the International Journal of Molecular Sciences.
Despite significant advancements in recent years, the comprehension of the molecular mechanisms underlying both inherited and acquired neurological diseases still represents a scientific challenge and requires further efforts to be fully achieved. Undeniably, the employment of omics technologies, and especially their integration into the so-called multi-omics approach, has improved our understanding of the molecular basis of diseases affecting the nervous system. Moreover, the possibility of combining datasets from different omics analyses allows us to identify the biomarkers that are suitable for the monitoring of disease progression and eventually develop innovative therapeutical strategies, including the recognition of new molecular candidates for pharmacological targeting.
The aim of this Special Issue is to collect original research articles and review papers dealing with omics technologies and their applications to the investigation of the pathomechanisms underling human disorders affecting the nervous system. Technical papers describing innovative approaches and computational bioinformatic advancements in this field are also highly welcome.
Dr. Francesco Pezzini
Dr. Stefano Doccini
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurological diseases
- molecular mechanisms
- neurodegeneration
- omics
- bioinformatics
- disease biomarkers
- biochemical pathways
- diagnostic and therapeutic targets
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