Role and Application of Stem Cells in Regenerative Medicine (Volume 5)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (20 September 2025) | Viewed by 2429
Special Issue Editors
Interests: stem cells; biomaterials; regenerative medicine
Special Issues, Collections and Topics in MDPI journals
Interests: regenerative medicine; stem cells; oral stem cells; biomaterials; extracellular vesicles; exosomes; epithelial–mesenchymal transition
Special Issues, Collections and Topics in MDPI journals
Interests: regenerative medicine; stem cells; biomaterials; extracellular vesicles; exosomes; cardiac regeneration; cardiomyocytes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue is the fifth version of our previous Special Issue "Role and Application of Stem Cells in Regenerative Medicine”.
https://www.mdpi.com/journal/ijms/special_issues/stem_cells_med
https://www.mdpi.com/journal/ijms/special_issues/stem_cells_med2
https://www.mdpi.com/journal/ijms/special_issues/stem_cells_med3
https://www.mdpi.com/journal/ijms/special_issues/59769A8GJ0
Mesenchymal stem cells (MSCs) are currently being used in preclinical and clinical trials for their ability to promote wound healing and tissue regeneration.
In particular, oral-derived mesenchymal stem cells (oral-MSCs) are accessible and can be collected and used in regenerative medicine, avoiding ethical concerns. They can be derived from different oral tissues, such as human exfoliated deciduous teeth (SHED), periodontal ligaments (PDLSCs), dental follicles (as progenitor (P) cells, DFPCs), apical papilla (SCAP), dental pulp (DPSCs), and gingival tissue (GMSCs), and possess multipotential properties and high proliferation and differentiation abilities. Moreover, oral MSCs have paracrine and immunomodulatory capacities, representing an innovative tool for the treatment of various degenerative and traumatic processes, including skeletal and maxilla-facial degeneration, trauma or ischemia injuries, and neurodegenerative and immune disorders.
This new Special Issue will comprise a selection of research papers and reviews contributing to the evaluation of the aptitude of oral-MSCs and their secretome for tissue regeneration, thereby facilitating the fabrication of 3D living constructs for future clinical applications.
Moreover, in vitro and in vivo studies on the molecular mechanisms involved in tissue regeneration are of interest, since they will provide a possibly important contribution to the development of stem-cell-based regeneration strategies and to the identification of key biological regulation processes that remain uncovered.
Prof. Dr. Oriana Trubiani
Dr. Francesca Diomede
Dr. Jacopo Pizzicannella
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mesenchymal stem cells
- tissue regeneration
- regenerative medicine
- immunomodulatory process
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
