Plant Natural Products for Human Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 December 2025 | Viewed by 1575
Special Issue Editor
Interests: antioxidants; antioxidant activity; lipid peroxidation; oxidative stress; reactive oxygen species
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Natural products of plant origin have long been recognized for their therapeutic potential, serving as a rich source of bioactive compounds with diverse therapeutic effects and molecular mechanisms. Historically, many modern drugs are derived from phytochemicals such as alkaloids, flavonoids, terpenoids, and polyphenols, which interact at the cellular and molecular levels to modulate physiological pathways. Advances in molecular biology and phytochemistry have deepened our understanding of how these natural compounds affect human health by targeting specific enzymes, receptors, and signalling cascades involved in the pathogenesis of noncommunicable diseases such as cancer, cardiovascular, and neurodegenerative conditions.
This Special Issue aims to highlight recent advances in the elucidation of the molecular mechanisms and bioactivity of plant-derived compounds. It will cover research aimed at the isolation, structural characterization, and bioassays of natural products, as well as their mechanisms of action at the molecular level, including gene expression modulation, enzyme inhibition, antioxidant activity, and immune system regulation. In addition, it will cover emerging approaches such as molecular docking and omics technologies to optimize the therapeutic efficacy of plant natural products. By integrating interdisciplinary research, this collection seeks to accelerate the translation of phytochemicals into novel, effective, and safe interventions for human health and disease management.
Dr. Rumyana Simeonova
Guest Editor
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Keywords
- medicinal plants
- phytochemistry
- bioactive compounds
- metabolomics
- proteomics
- antioxidants
- signal transduction
- immunomodulation
- phytopharmacology
- ethnopharmacology
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