International Journal of Molecular Sciences

Inflammatory Bowel Disease: Pathogenesis and Novel Therapeutic Approaches

edited by Francisco Giner

submission deadline 25 Dec 2026 | 2 articles | Viewed by 5806 | Submission Open

Keywords: coeliac disease; microscopic colitis; Crohn’s disease; ulcerative colitis; microbiota; biological therapies; refractory disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in Graphene-Based Nanocomposites and Perspectives on Their Design

edited by Aleksey E. Kuznetsov

submission deadline 25 Dec 2026 | 3 articles | Viewed by 5648 | Submission Open

Keywords: graphene; graphene oxide; nanocomposite; synthesis; computational study; characterization; application; design

(This special issue belongs to the Section Molecular Nanoscience)

Applications of Mass Spectrometry in the Analysis of Bioactive and Plant Organic Compounds

edited by

Marisabel Mecca

submission deadline 25 Dec 2026 | 3 articles | Viewed by 5628 | Submission Open

Keywords: mass spectrometry; VOCs; bioactive compounds; plant organic compounds; pharmaceutical research; metabolites

(This special issue belongs to the Section Biochemistry)

Mitigating Metal Toxicity: Contaminated Environment, Animal Studies and Human Health

edited by

Agnieszka Scibior

,

Manuel Aureliano

and

Juan Llopis

submission deadline 25 Dec 2026 | 3 articles | Viewed by 5597 | Submission Open

Keywords: heavy metal toxicity; heavy metal pollution; heavy metal bioaccumulation and interactions; health risk; mechanistic analysis; dysregulation of cellular homeostasis; natural plant bioactive compounds; human diseases; environmental pollution; in vitro/animal studies; innovative strategies; polyoxometalates (POMs); metal-organic frameworks (MOFs)

(This special issue belongs to the Section Molecular Toxicology)

Liver Disease and Primary Liver Cancer: Translational Advances and Therapeutic Perspectives

edited by

Cristian Turato

submission deadline 25 Dec 2026 | 6 articles | Viewed by 5474 | Submission Open

Keywords: liver disease; hepatocellular carcinoma; cholangiocarcinoma; molecular mechanisms; translational research; 3D models and organoids; biomarkers and therapeutic strategies; MASH/MASLD: pathogenesis, diagnosis, and management; primary liver cancer: pathogenesis, detection, and treatment; inflammation in liver disease; 3D liver models; microbiota and liver disease; mechanisms of damage and repair: ischemia-reperfusion injury; cellular pathology in acute and chronic liver damage of different origin; biomarkers in liver disease: emerging methods and potential applications; immunology in the liver—from homeostasis to disease

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Nature-Inspired and Synthetic Compounds: New Frontiers in Bioactivity and Drug Discovery

edited by

Alina Bora

and

Luminita Crisan

submission deadline 25 Dec 2026 | 5 articles | Viewed by 5449 | Submission Open

Keywords: natural and synthetic products; drug discovery and development; drug repurposing; artificial intelligence and machine learning; biological evaluation; healthcare; green and sustainable chemistry; natural and synthetic drug applications

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Exploring Abiotic Stress in Plants: Mechanisms, Adaptations, and Mitigation Strategies (2nd Edition)

edited by

Tarek Alshaal

submission deadline 25 Dec 2026 | 4 articles | Viewed by 5423 | Submission Open

Keywords: abiotic stress; plant physiology; stress tolerance; crop resilience; molecular mechanisms; biotechnological interventions

(This special issue belongs to the Section Molecular Plant Sciences)

Innovative Therapeutic Approaches to Endocrine Disorders

edited by

Gilberta Giacchetti

and

Emanuele-Salvatore Scarpa

submission deadline 25 Dec 2026 | 3 articles | Viewed by 5403 | Submission Open

Keywords: endocrine disorders; osteoporosis; diabetes; obesity; synthetic drugs; nutraceuticals; biomarkers

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Immunological Control of Vascular Plasticity: Insights into Arteriogenesis, Angiogenesis, and Atherosclerosis

edited by

Elisabeth Deindl

and

Hector A. Cabrera-Fuentes

submission deadline 25 Dec 2026 | 2 articles | Viewed by 5366 | Submission Open

Keywords: vascular plasticity; arteriogenesis; angiogenesis; atherosclerosis; immune modulation; inflammation and vascular remodeling; translational vascular immunology; smooth muscle cell-/endothelial cell proliferation; sterile inflammation; collateral artery growth

(This special issue belongs to the Section Molecular Immunology)

Advances in Traits in Animals and Aquatic Species, and Their Improvement Technologies

edited by

Lishi Yang

submission deadline 25 Dec 2026 | 5 articles | Viewed by 5350 | Submission Open

Keywords: biotechnology; genetic breeding; stress responses; epigenetics; non-coding RNAs; gene regulation; molecular ecology; animals; aquaculture; development

(This special issue belongs to the Section Molecular Biology)

Antimicrobial Nanoparticles: Mechanisms, Applications, and Future Directions

edited by

Carmen Curutiu

and

Alina Maria Holban

submission deadline 25 Dec 2026 | 5 articles | Viewed by 5330 | Submission Open

Keywords: antimicrobial activity; nanoparticles; biofilm nano-modulators; antibiotic resistence; wastewater treatment; preservative properties of nanoparticles

(This special issue belongs to the Section Molecular Microbiology)

Molecular Endocrine Regulation in Health and Diseases

edited by Fady Hannah-Shmouni

submission deadline 25 Dec 2026 | 1 articles | Viewed by 5026 | Submission Open

Keywords: exposome and endocrine disruptors; endocrine-disrupting chemicals (EDCs); environmental toxicology and hormonal health; epigenetics and endocrine function; endocrine regulation and chronic disease; public health and exposure mitigation; endocrine disruptors in the home and community

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Eukaryotic DNA Replication—from Bench to Bedside

edited by Heinz-Peter Nasheuer

submission deadline 25 Dec 2026 | 1 articles | Viewed by 4969 | Submission Open

Keywords: genome stability; cell cycle; DNA replication; chromatin replication; replication origins—selection, licensing and firing; replication forks—smoothly progressing and under stress; role of DNA replication in cancer and other human diseases; disease treatment opportunities

(This special issue belongs to the Section Molecular Genetics and Genomics)

Heat Shock Proteins (HSPs): Biological Functions and Mechanisms of Actions

edited by

Soumya Patnaik

and

Gregory Blatch

submission deadline 25 Dec 2026 | 4 articles | Viewed by 4951 | Submission Open

Keywords: heat shock proteins; apoptosis; immune cell activation; stress responses; misfolded proteins; cellular chaperones; cell signaling

(This special issue belongs to the Section Biochemistry)

Targeting Epigenetic Complexes and Alternative Protein Degradation Pathways in Medicinal Chemistry

edited by Jean Leandro Dos Santos

submission deadline 25 Dec 2026 | 2 articles | Viewed by 4840 | Submission Open

Keywords: protein degradation; LYTAC; AUTAC; ATTEC; epigenetics; NuRD; HDAC; BRD; SWI/SNF; PRC2; chromatin; conjugates; lysosome; autophagy; drug discovery

(This special issue belongs to the Section Biochemistry)

Antiviral Drug Targets: Structure, Function, and Drug Design—3rd Edition

edited by

Mattia Mori

and

Ilaria Vicenti

submission deadline 25 Dec 2026 | 3 articles | Viewed by 4801 | Submission Open

Keywords: viral infections; drug design; protein structures; functional studies; viruses; antiviral drugs

(This special issue belongs to the Section Molecular Pharmacology)

Natural Compounds: Impact on Health and Disease

edited by

Jaehoon Bae

submission deadline 25 Dec 2026 | 3 articles | Viewed by 4678 | Submission Open

Keywords: natural compounds; bioactive molecules; disease prevention; phytochemicals; functional food; molecular mechanisms; therapeutic potential; oxidative stress; immune modulation

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Medicinal Plants, Animal-Derived Products, and Natural Compounds: Roles in Health and Disease

edited by

Vitor Engrácia Valenti

submission deadline 25 Dec 2026 | 5 articles | Viewed by 4336 | Submission Open

Keywords: natural bioactive compounds; medicinal plants; animal-derived products; marine natural products; chronic diseases; inflammation; oxidative stress; molecular mechanisms; therapeutic peptides; natural toxins; antioxidant activity; anti-inflammatory agents; nanoformulations; nanodelivery systems; drug delivery; pharmacological properties; translational research; integrative medicine; natural therapeutics; disease prevention

(This special issue belongs to the Section Bioactives and Nutraceuticals)

MicroRNAs in Physiology and Pathophysiology

edited by Małgorzata Guz

submission deadline 25 Dec 2026 | 3 articles | Viewed by 4335 | Submission Open

Keywords: miRNA; cell physiology; metabolism; cancer; biomarkers; disease; molecular mechanisms; diagnosis; therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Research on Bioactive Natural Products: 2nd Edition

edited by

Alexandros Tsoupras

submission deadline 25 Dec 2026 | 1 articles | Viewed by 4289 | Submission Open

Keywords: chronic disorders; bioactives; natural sources; sustainable sources; biomolecular; structure–activity relationship; synergism; health promoting; bio-functional; products; supplements; nutraceuticals; drugs

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Molecular Research on the Pathology and Treatment of Sepsis and Non-Infectious Inflammatory Conditions

edited by

Andressa Freitas

submission deadline 25 Dec 2026 | 3 articles | Viewed by 4016 | Submission Open

Keywords: sepsis; comorbidities; inflammation; molecular mechanisms; cytokine signaling; oxidative stress; leukocyte recruitment; therapeutic targets

(This special issue belongs to the Section Molecular Immunology)

Highlights in Pathophysiology of the Musculoskeletal System, 3rd Edition

edited by

Marta Anna Szychlinska

,

Rosario Barone

and

Giovanna Calabrese

submission deadline 25 Dec 2026 | 2 articles | Viewed by 4005 | Submission Open

Keywords: musculoskeletal; skeletal; tendon; ligament; intervertebral; articular cartilage; osteoarthritis; rheumatoid arthritis; sarcopenia; muscle wasting; osteoporosis; bone necrosis; synovium; pain; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Insights in Diabetes

edited by

Mariann Harangi

and

Ferenc Sztanek

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3999 | Submission Open

Keywords: insulin signalling pathway; pancreatic beta-cell dysfunction; oxidative stress; epigenetic modifications; metabolic memory; small regulatory RNAs (miRNAs); inflammation and insulin resistance; glucagon-like peptide-1 (GLP-1); glucose-dependent insulinotropic polypeptide (GIP); molecular therapeutic targets; glucose homeostasis regulation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Molecular Advances in Assisted Reproductive Technologies

edited by

Sung Tae Kim

submission deadline 25 Dec 2026 | 1 articles | Viewed by 3875 | Submission Open

Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology; morpho kinetics; in vitro gametogenesis; in vitro oocyte maturation; reproductive tissue cryopreservation; artificial intelligence (AI)

(This special issue belongs to the Section Molecular Biology)

Recent Advances in Molecular Targets for Treatment and Drug Delivery in Tumors: 2nd Edition

edited by

Emily Capone

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3845 | Submission Open

Keywords: targeted therapy; tumor; molecular target; drug delivery; drug design

(This special issue belongs to the Section Molecular Oncology)

Advances in Obesity Research: Metabolic Pathways and Pathophysiological Factors

edited by Aleksandra Stefanović

submission deadline 25 Dec 2026 | 4 articles | Viewed by 3715 | Submission Open

Keywords: obesity; inflammation; oxidative stress; obesity-related diseases; adypocitokines

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Targeting MAPK in Human Diseases

edited by

Elisabetta Rovida

submission deadline 25 Dec 2026 | 1 articles | Viewed by 3683 | Submission Open

Keywords: ERK; DUSP; cancer; inflammation; neurodegenerative diseases; autoimmune diseases; targeted therapy; cell signaling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Pulmonary Hypertension and Interstitial Lung Diseases: Mechanisms and Treatments

edited by

Katarzyna B. Lewandowska

and

Monika Szturmowicz

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3630 | Submission Open

Keywords: pulmonary hypertension; interstitial lung disease; lung fibrosis; pulmonary hemodynamics; pulmonary function testing; pathogenesis; prognosis; survival; treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Cellular Mechanisms Underlying Taste and Smell

edited by

Naina Bhatia-Dey

and

Thomas Heinbockel

submission deadline 25 Dec 2026 | 4 articles | Viewed by 3608 | Submission Open

Keywords: olfaction; anosmia; hyposmia; ageusia; dysgeusia; gustation; chemesthesis; receptors; chemosensory processing; epigenome

(This special issue belongs to the Section Molecular Biology)

Molecular Research and Application of Platelet-Rich Plasma

edited by

Jorge U. Carmona

submission deadline 25 Dec 2026 | 1 articles | Viewed by 3590 | Submission Open

Keywords: platelet-rich plasma; fibrin scaffold; regenerative medicine; molecular biology; translational medicine

(This special issue belongs to the Section Molecular Biology)

Drug and Non-Drug Treatment of Cerebral Diseases

edited by

Silvia Carloni

submission deadline 25 Dec 2026 | 1 articles | Viewed by 3522 | Submission Open

Keywords: cerebral diseases; cerebral ischemia; neonatal hypoxic-ischemic encephalopathy (HIE); neuroprotection; therapeutic hypothermia; neurorehabilitation; oxidative stress; stem cell therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Tools in Environmental Microbiology

edited by

Živilė Strazdaitė-Žielienė

and

Juliana Lukša

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3498 | Submission Open

Keywords: environmental microbiology; molecular methods; microbial community analysis; low-abundance microorganisms; microbial identification; environmental DNA; next-generation sequencing (NGS); high-throughput sequencing

(This special issue belongs to the Section Molecular Microbiology)

The Role of Medicinal Plants in Health and Diseases

edited by

Hamza El Moudden

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3472 | Submission Open

Keywords: medicinal plants; phytochemicals; natural products; pharmacological activity; herbal medicine; drug discovery; traditional medicine; therapeutic potential

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Advances in the Role of Cytoskeletal Proteins in Diseases

edited by

Urko Del Castillo

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3471 | Submission Open

Keywords: cytoskeleton; microtubules; actin filaments; intermediate filaments; neurodegeneration; cancer metastasis; cell migration; cellular mechanotransduction; cytoskeletal remodeling

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms and Therapeutic Targets in Systemic Vasculitis

edited by Andrés González-García

submission deadline 25 Dec 2026 | 1 articles | Viewed by 3405 | Submission Open

Keywords: vasculitis; ANCA-associated vasculitis; EGPA; complement activation; molecular immunopathogenesis; endothelial dysfunction; cytokine signaling; biomarkers; therapeutic targets; autoimmunity

(This special issue belongs to the Section Molecular Immunology)

Exploring Molecular Mechanisms of Prostate Cancer

edited by

Estefania Labanca

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3180 | Submission Open

Keywords: genetic alterations; signlaing pathways; cellular dysregulation; non-coding RNAs; epigenetics; tumor microenvironment; metabolic factors; therapuetic targeting; multi-modal approaches

(This special issue belongs to the Section Molecular Oncology)

Bioactive Molecules in Infection and Toxicity: Antimicrobial Peptides and Drug-Induced Damage in Disease Models

edited by

Oleksii Skorokhod

submission deadline 25 Dec 2026 | 3 articles | Viewed by 3174 | Submission Open

Keywords: antimicrobial peptides (AMPs); infectious diseases; drug-induced toxicity; disease models; therapeutic strategies; drug delivery systems

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Gene Regulation in Endocrine Disease, 2nd Edition

edited by

Alberto Falchetti

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3171 | Submission Open

Keywords: gene regulation; endocrine disease; endocrinology; diabetes mellitus; thyroid disorders

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Gene, Genomics, and Molecular Breeding in Cruciferae Plants (3rd Edition)

edited by

Maoteng Li

submission deadline 25 Dec 2026 | 3 articles | Viewed by 3155 | Submission Open

Keywords: Cruciferae plants; genome analysis; genetic dissection; gene function; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Latest Molecular Advances in Prostate Cancer

edited by Rejane Maira Góes

submission deadline 25 Dec 2026 | 2 articles | Viewed by 3138 | Submission Open

Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy

(This special issue belongs to the Section Molecular Oncology)

Molecular and Physiological Strategies for Plant Drought Resilience

edited by

Mariapina Rocco

submission deadline 25 Dec 2026 | 1 articles | Viewed by 3090 | Submission Open

Keywords: abiotic stress; reactive oxygen species; oxidative stress; adaptive response; signaling pathways; phytohormones; physiological adaptation; molecular adaptation

(This special issue belongs to the Section Molecular Plant Sciences)

Psychobiotics as Next-Generation Probiotics: A Holistic Approach to Mental Health and Gut–Brain Axis Modulation

edited by

Edyta Juszczuk-Kubiak

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2983 | Submission Open

Keywords: probiotics; gut microbiota; gut–brain axis; mental health

(This special issue belongs to the Section Molecular Biology)

The Role of Complement Regulation in Kidney Disease

edited by Jasmina Marković Lipkovski

submission deadline 25 Dec 2026 | 2 articles | Viewed by 2886 | Submission Open

Keywords: complement system; kidney disease; glomerulonephritis; C3 glomerulopathy; membranous nephropathy; complement regulation; innate immunity; molecular pathology

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Biology of 3D Cell and Tissue Culture Systems: Benefits to Research and Disease Diagnostics

edited by

Thomas J. Goodwin

submission deadline 25 Dec 2026 | 2 articles | Viewed by 2835 | Submission Open

Keywords: 3D physiological relevance vs. 2D biology, 3D research, and diagnostic systems; evolving 3D “omics” applications; research and clinical medicine; drug applications; toxicity evaluations; “Omics” ; spatial biology of 3D

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Gut Microbiota-Derived Metabolites in Human Health and Disease

edited by Zeneng Wang

submission deadline 25 Dec 2026 | 3 articles | Viewed by 2808 | Submission Open

Keywords: microbiome; microbiota; gut; metabolomics; health; disease; inflammation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Recent Advances in Genome-Edited Animal Models

edited by Takayuki Sakurai and

Masahiro Sato

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2769 | Submission Open

Keywords: genome editing; prime editing; base editing; CRISPRa/CRISPRi; knock-in/out; conditional genome editing; multiplex genome editing; manipulation of early embryos and germ cells; in vivo gene delivery; genome-edited animals; disease animal model

(This special issue belongs to the Section Molecular Genetics and Genomics)

Progress in Prevention and Treatment of Cardiovascular Diseases and Arrhythmias

edited by

Narcis Tribulova

submission deadline 25 Dec 2026 | 2 articles | Viewed by 2745 | Submission Open

Keywords: translational research; novel animal models; novel treatment targets; pleiotropic drugs; harnessing of molecular H

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular and Genetic Insights into Neuropsychiatric Disorders: From Mechanisms to Management

edited by

James Alan Bourgeois

submission deadline 25 Dec 2026 | 3 articles | Viewed by 2703 | Submission Open

Keywords: psychiatry; neurology; psychotic disorders; depressive disorders; neurocognitive disorders; neuropsychiatry; genetics; psychopharmacology; neuromodulation; genome-wide association studies (GWAS); transcriptomics; epigenetics; gene-environment interactions

(This special issue belongs to the Section Molecular Neurobiology)

Atherosclerosis and Comorbidities: From Molecular Pathogenesis to Diagnosis and Therapeutic Targets

edited by

Alexandr Ceasovschih

,

Victoriţa Şorodoc

and

Yusuf Ziya Şener

submission deadline 25 Dec 2026 | 1 articles | Viewed by 2696 | Submission Open

Keywords: atherosclerosis; comorbidities; lipidology; inflammation; obesity; arterial stiffness; vascular remodeling; cardiovascular risk; cardiovascular diseases; targeted therapies; lifestyle

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Deciphering the Molecular Mechanisms That Regulate Plant Disease and Immunity

edited by Bourlaye Fofana and

Champa Wijekoon

submission deadline 25 Dec 2026 | 3 articles | Viewed by 2666 | Submission Open

Keywords: plants; biotic stressors; molecular mechanisms; omics technologies; plant immunity

(This special issue belongs to the Section Molecular Plant Sciences)

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