Molecular Research on the Pathology and Treatment of Sepsis and Non-Infectious Inflammatory Conditions
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 60
Special Issue Editor
Special Issue Information
Dear Colleagues,
Sepsis and non-infectious inflammatory disorders are significant global health challenges, and they are associated with a high prevalence of morbidity and mortality. Although our understanding of immune responses has advanced in recent years, the complex interactions within inflammatory networks and how they become dysregulated during disease remain incompletely understood. Molecular studies have been crucial in elucidating the mechanisms that promote inflammation, identifying biomarkers, and suggesting novel therapeutic targets.
This Special Issue welcomes the submission of original research and reviews that address the molecular mechanisms involved in sepsis and sterile inflammation, including leukocyte recruitment, efferocytosis, cytokine signaling, oxidative stress, and resolution pathways. We welcome contributions that investigate the impact of comorbidities on the progression of disease and provide molecular insights into how underlying conditions influence inflammation and clinical outcomes. Contributions related to novel anti-inflammatory therapies, drug development, and translational research are also encouraged.
This Special Issue aims to enhance our understanding of inflammation in order to support the development of innovative therapies.
Dr. Andressa Freitas
Guest Editor
Manuscript Submission Information
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Keywords
- sepsis
- comorbidities
- inflammation
- molecular mechanisms
- cytokine signaling
- oxidative stress
- leukocyte recruitment
- therapeutic targets
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