Immunological Control of Vascular Plasticity: Insights into Arteriogenesis, Angiogenesis, and Atherosclerosis
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 39
Special Issue Editors
Interests: cardiovascular research; immunology
Special Issues, Collections and Topics in MDPI journals
Interests: basic science and clinical research in organ protection against acute ischaemia/reperfudion injury with a special focus on cardiac protection and acute inflammation and remodeling; basic science and translational research in atherosclerosis and chronic inflammation processes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Blood vessels possess an extraordinary capacity for adaptation, responding dynamically to physiological demands and pathological insults. Recent advances have revealed that this plasticity is not governed solely by hemodynamic forces or growth factor signaling, but is deeply intertwined with immune regulation. Innate and adaptive immune responses modulate vascular remodeling at every stage: from the initiation of arteriogenesis and the fine-tuning of angiogenic sprouting, to the progression and destabilization of atherosclerotic plaques.
This Special Issue will bring together ground-breaking research and distinguished perspectives at the intersection of vascular biology and immunology. We seek contributions that dissect the molecular and cellular mechanisms through which immune cells influence endothelial behavior, mural cell recruitment, extracellular matrix remodeling, and vascular integrity. Particularly welcome are studies integrating single-cell and spatial omics, advanced imaging, and in vivo modeling to illuminate immune–vascular interactions in both health and disease.
By bridging fundamental science with translational insight, this Special Issue aims to define a new framework for targeting immune pathways to modulate vascular growth, restore perfusion in ischemic tissues, or attenuate vascular inflammation. We invite original articles, expert reviews, and perspective pieces that will help shape the future of immunovascular medicine.
Prof. Dr. Elisabeth Deindl
Prof. Dr. Hector A. Cabrera-Fuentes
Guest Editors
Manuscript Submission Information
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Keywords
- vascular plasticity
- arteriogenesis
- angiogenesis
- atherosclerosis
- immune modulation
- inflammation and vascular remodeling
- translational vascular immunology
- smooth muscle cell-/endothelial cell proliferation
- sterile inflammation
- collateral artery growth
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