Progress in Prevention and Treatment of Cardiovascular Diseases and Arrhythmias
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 16
Special Issue Editor
Interests: inflammation; redox disorder; heart diseases; arrhythmia substrate; cardiac connexin-43; Cx-hemichannels; antiarrhythmic mechanisms of tested agents; omega-3 fatty acids; melatonin
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Special Issue Information
Dear Colleagues,
Although cardiology has progressed dramatically, cardiovascular diseases (CVDs) and malignant arrhythmias remain the most common cause of death worldwide, and much remains to be accomplished. The next major steps should include more vigorous and widespread prevention as well as the application of the recent remarkable advances in genomics. The best way to avoid cardiovascular diseases (CVDs) and cardiac arrhythmias is to prevent their development. One of the most important risk factors of CVDs is an unhealthy lifestyle. Regular medical screening can reveal warning signs or biomarkers like increased blood pressure, blood glucose, lipid profile, C-reactive protein, and body mass index, which indicates a predisposition to diseases before symptoms manifest. Screenings can improve health outcomes via lifestyle modifications, such as diet, exercise, cold acclimation, or treatment interventions. There is a need to mitigate climate change due to the greenhouse gas emission-associated cardiovascular risk, particularly in vulnerable populations. Recent advancements highlight the potential of naturally derived bio-products with epigenetic properties which offer protection against CVDs and cardiac arrhythmias. To reach the optimal level of protection, a multi-targeted approach directed towards more than one intracellular signaling pathway or cell type is required. One of the most studied targets are mitochondria because of their key involvement in reactive oxygen species (ROS) production facilitating chronic low-grade inflammation that predispose to CVDs and arrhythmias. On the other hand, hydrogen medicine is one of the most promising novel strategies for the prevention and/or treatment of these adverse conditions via molecular hydrogen. "There is still time to share your science’’.
Dr. Narcis Tribulova
Guest Editor
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Keywords
- translational research
- novel animal models
- novel treatment targets
- pleiotropic drugs
- harnessing of molecular H
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