Highlights in Pathophysiology of the Musculoskeletal System, 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 November 2025 | Viewed by 48
Special Issue Editors
Interests: cartilage tissue engineering; mesenchymal stem cells; osteoarthritis; articular cartilage morphology
Special Issues, Collections and Topics in MDPI journals
Interests: cell biology; physiology; exercise performance; nutition; sports science; morphology; pathopysiology
Special Issues, Collections and Topics in MDPI journals
Interests: regenerative biomaterials; bone tissue engineering; osteoconduction; osteoinduction; osteointegration
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The musculoskeletal system is an organ system that provides support, shape, and stability, and enables the movement of joints in the human body. It mainly consists of bones, skeletal muscles, tendons, ligaments, intervertebral discs, and articular cartilage tissue, as well as their associated nerves and blood vessels. Due to their primary functions, they are by far the most commonly injured tissues in the body, and musculoskeletal disorders represent one of the most common health problems worldwide. During the past few decades, with the advancement of research and technology, much has been discovered concerning the pathophysiological knowledge of the musculoskeletal system. Novel molecular targets have been identified for therapeutic approaches. Innovative methodologies such as tissue engineering, regenerative medicine, gene therapies, drug delivery systems, microgravity conditions, and nutritional interventions have facilitated the development of our understanding of mechanisms of musculoskeletal disorders such as osteoarthritis, rheumatoid arthritis, sarcopenia, muscle wasting, osteoporosis, bone necrosis, and many others.
In this Special Issue of the International Journal of Molecular Sciences, we focus our attention on the latest discoveries and developments in musculoskeletal system pathophysiology at a molecular level and provide a comprehensive update on the literature accessible to scientists in the field. Thus, we wish to invite investigators from basic, pathophysiological, and translational musculoskeletal system research or closely related disciplines to contribute original articles, reviews, communications, and conceptual papers.
Dr. Marta Anna Szychlinska
Dr. Rosario Barone
Dr. Giovanna Calabrese
Guest Editors
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Keywords
- musculoskeletal
- skeletal
- tendon
- ligament
- intervertebral
- articular cartilage
- osteoarthritis
- rheumatoid arthritis
- sarcopenia
- muscle wasting
- osteoporosis
- bone necrosis
- synovium
- pain
- inflammation
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