Molecular Endocrine Regulation in Health and Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: 25 December 2025 | Viewed by 22
Special Issue Editor
Special Issue Information
Dear Colleagues,
The exposome—the totality of environmental exposures from conception onward—plays a critical role in endocrine health and disease. Endocrine-disrupting chemicals (EDCs), found in household products, plastics, air pollutants, food packaging, and water sources, interfere with hormonal signaling, leading to metabolic disorders, reproductive dysfunction, thyroid imbalances, and neurodevelopmental conditions. These exposures are particularly concerning due to their cumulative effects over a lifetime, their transgenerational impact, and their potential to exacerbate chronic diseases, including obesity, diabetes, and hormone-dependent cancers.
This Special Issue will explore the molecular mechanisms by which EDCs and other environmental contaminants disrupt endocrine function, highlighting key pathways such as nuclear receptor signaling, epigenetic modifications, oxidative stress, and gut microbiome interactions. Additionally, we welcome research on advanced biomonitoring techniques, risk assessment models, and public health interventions aimed at mitigating exposure.
We invite original research, reviews, and perspectives from diverse fields, including molecular endocrinology, toxicology, environmental health sciences, and systems biology, to deepen our understanding of how the exposome shapes endocrine health across the lifespan.
Dr. Fady Hannah-Shmouni
Guest Editor
Manuscript Submission Information
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Keywords
- exposome and endocrine disruptors
- endocrine-disrupting chemicals (EDCs)
- environmental toxicology and hormonal health
- epigenetics and endocrine function
- endocrine regulation and chronic disease
- public health and exposure mitigation
- endocrine disruptors in the home and community
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