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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Tumor Necrosis Factor and Inflammatory Diseases

edited by Salah Amasheh

submission deadline 30 Sep 2025 | Viewed by 278 | Submission Open

Keywords: tumor necrosis factor; inflammatory chronic disease; experimental biomedicine; epithelium; pathophysiology; immunology; therapeutic stategies

(This special issue belongs to the Section Molecular Oncology)

Molecular Pathology and Next-Generation Biomarkers in Nephrology

edited by

Marijn Speeckaert

submission deadline 30 Sep 2025 | 1 articles | Viewed by 274 | Submission Open

Keywords: nephrology; genetic mutations; epigenetics; next-generation biomarkers; proteomics; metabolomics; single-cell sequencing; spatial transcriptomics; liquid biopsy; cfDNA; exosomes; microRNAs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Computational Studies of Ionic Liquids and Their Analogues

edited by

Iuliia Voroshylova

and Elisabete Ferreira

submission deadline 30 Sep 2025 | Viewed by 269 | Submission Open

Keywords: ionic liquids; deep eutectic solvents; molecular dynamics; density functional theory; COSMO-RC; machine learning; ab initio

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Pathophysiology of Dermatitis: Mechanisms and Therapeutic Perspectives

edited by

Natalia Karolina Galińska

submission deadline 30 Sep 2025 | Viewed by 237 | Submission Open

Keywords: immune-mediated skin diseases; molecular mechanism of dermatitis; new therapeutic substances and treatment techniques; dermatitis; skin diseases

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Forensics and the Genetic Foundations of Forensic Biology

edited by

Laura Caine

submission deadline 30 Sep 2025 | Viewed by 203 | Submission Open

Keywords: molecular forensics; forensic genetics; epigenetics; biological fluid identification; forensic microbiology; sexual assault

(This special issue belongs to the Section Molecular Biology)

Advances in Biomathematics, Computational Biology, and Bioengineering

edited by

Grzegorz Matyszczak

submission deadline 30 Sep 2025 | 1 articles | Viewed by 201 | Submission Open

Keywords: biomathematics; machine learning; artificial intelligence; data science; systems biology; reaction– diffusion systems; nonlinear dynamics; bioreactors; biochemical reaction engineering

(This special issue belongs to the Section Molecular Informatics)

New Insights into Lactoferrin: 2nd Edition

edited by

Antimo Cutone

and

Giovanni Musci

submission deadline 30 Sep 2025 | Viewed by 181 | Submission Open

Keywords: lactoferrin; lactoferrin structure; lactoferrin functions; infection; inflammation; iron homeostasis; oxidative stress; lactoferrin bioavailability

(This special issue belongs to the Section Molecular Immunology)

Role of Mutations and Polymorphisms in Various Diseases: 2nd Edition

edited by

Anna Cieslinska

submission deadline 30 Sep 2025 | Viewed by 176 | Submission Open

Keywords: nutrigenomics; polymorphism; SNPs; mutations; predisposition; correlation; diversity; deletion; insertion

(This special issue belongs to the Section Molecular Genetics and Genomics)

The Regulation of Microorganisms on Human Endocrine and Metabolic Systems

edited by Thi Phuong Nam Bui and Valentina Tremaroli

submission deadline 30 Sep 2025 | Viewed by 167 | Submission Open

Keywords: human gut microbiome; endocrine signaling; metabolism; obesity; type 2 diabetes; cardiometabolic diseases

(This special issue belongs to the Section Molecular Microbiology)

Future Challenges and Innovation in Gynecological Oncology

edited by

Alejandro Herreros-Pomares

submission deadline 30 Sep 2025 | Viewed by 165 | Submission Open

Keywords: gynecologic oncology; molecular biomarkers; personalized medicine; ovarian cancer; immunotherapy; tumor microenvironment; drug resistance; translational research

(This special issue belongs to the Section Molecular Oncology)

Molecular Research in Airway Diseases

edited by

Giusy Daniela Albano

submission deadline 30 Sep 2025 | Viewed by 160 | Submission Open

Keywords: airway diseases; inflammation; immunopharmacology; cellular models; biomarkers; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Recent Advances in New Biomarkers for Cancers

edited by

Maria Panagopoulou

submission deadline 30 Sep 2025 | Viewed by 159 | Submission Open

Keywords: biomarkers; cancer research; liquid biopsy; epigenetic and genetic biomarkers; precision oncology; diagnosis; prognosis; prediction

(This special issue belongs to the Section Molecular Oncology)

Collagen and Its Derivatives in Tissue Engineering

edited by

István Hornyák

submission deadline 30 Sep 2025 | Viewed by 152 | Submission Open

Keywords: collagen derivatives; tissue engineering; in vitro experiments; in vivo investigations; material degradation

(This special issue belongs to the Section Biochemistry)

Algae-Derived Bioactives: Key Molecular Interactions Govern High-Value Applications

edited by Evan Stephens and Kirsten Heimann

submission deadline 30 Sep 2025 | Viewed by 151 | Submission Open

Keywords: microalgae; macroalgae; cyanobacteria; bioactive compounds; health and nutrition; algal food products; market analysis

(This special issue belongs to the Section Molecular Microbiology)

New Insights in the Mechanism of Obstetrical Complications: Prevention, Diagnosis, Monitoring, Treatment

edited by

Lucia Maria Procopciuc

and

Roxana Liana Lucaciu

submission deadline 30 Sep 2025 | Viewed by 147 | Submission Open

Keywords: high blood pressure; gestational diabetes; infections; preeclampsia; eclampsia; preterm labor; depresion; anxiety; pregnancy loss/miscarriage; stillbirth; premature membrane rupture; vaginal bleeding; placenta previa; anemia; intrauterine growth restriction; maternal risk factors; fetal risk factors; endothelial dysfunction; angiogenesis; oxidative stress; hormonal modifications; dyslipidemia; biochemical; genetic; epigenetic determinations; computational analysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Marine Fungi: From Molecular Biology to Biotechnology Application

edited by

Guang-Lei Liu

submission deadline 30 Sep 2025 | Viewed by 147 | Submission Open

Keywords: marine fungi; marine yeasts; marine filamentous fungi; biosynthesis; metabolic engineering; regulatory mechanism; functional biomolecules; exopolysaccharides; glycolipids; organic acids; biofuel; enzymes; cell factories; gene editing tools; fermentation optimization

(This special issue belongs to the Section Molecular Microbiology)

Genetic Engineering for Stress Tolerance in Crops

edited by

Muhammad Waseem

submission deadline 30 Sep 2025 | Viewed by 146 | Submission Open

Keywords: genetic engineering; stress tolerance; crop improvement; drought resistance; salt tolerance; heat stress; CRISPR; RNAi; genetic modification; synthetic biology; pest resistance; crop transformation; abiotic stress; environmental resilience

(This special issue belongs to the Section Molecular Plant Sciences)

Medicinal Plant Resources—from Molecular Studies to Sustainable Use

edited by Ekaterina Kozuharova

submission deadline 30 Sep 2025 | Viewed by 145 | Submission Open

Keywords: genetic improvement of medicinal plants; sustainable use; bioactive compounds

(This special issue belongs to the Section Molecular Plant Sciences)

Psychobiotics as Next-Generation Probiotics: A Holistic Approach to Mental Health and Gut–Brain Axis Modulation

edited by

Edyta Juszczuk-Kubiak

submission deadline 30 Sep 2025 | Viewed by 144 | Submission Open

Keywords: probiotics; gut microbiota; gut– brain axis; mental health

(This special issue belongs to the Section Molecular Biology)

Foundational Studies Using Model Systems for Molecular Insights into Metabolism, Aging, and Disease

edited by

James T. Arnone

submission deadline 30 Sep 2025 | Viewed by 143 | Submission Open

Keywords: Saccharomyces cerevisiae and yeasts; Caenorhabditis elegans and nematodes; Arabidopsis thaliana and plants; Drosophila melanogaster; Mus musculus; established and emerging model systems

(This special issue belongs to the Section Molecular Biology)

Structure-Based Design of Drugs and Other Bioactive Molecules

edited by

Antonio Carrieri

submission deadline 30 Sep 2025 | Viewed by 133 | Submission Open

Keywords: three-dimensional structure; molecular descriptor; molecular similarity; database searching; drug repositioning; target fishing; novel algorithm; data prediction

(This special issue belongs to the Section Molecular Informatics)

Applications of Polymers in Organic Functional Materials

edited by

Paola Manini

submission deadline 30 Sep 2025 | Viewed by 132 | Submission Open

Keywords: functional polymers; polymer synthesis; stimuli-responsive polymers; self-healing polymers; nanostructured polymers; polymer composites; smart materials; polymeric catalysts; polymers in (bio)electronics; polymers for sustainable processes

(This special issue belongs to the Section Macromolecules)

Molecular Advances in Assisted Reproductive Technologies

edited by

Sung Tae Kim

submission deadline 30 Sep 2025 | Viewed by 129 | Submission Open

Keywords: preimplantation genetic testing; embryo selection; in vitro fertilization; infertility; implantation failure; miscarriage; mosaicism; segmental aneuploidy; non-invasive technology; morpho kinetics; in vitro gametogenesis; in vitro oocyte maturation; reproductive tissue cryopreservation; artificial intelligence (AI)

(This special issue belongs to the Section Molecular Biology)

Biological Effects of Radiation on Human Cells and Tissues

edited by

Maria Paola Bertuccio

submission deadline 30 Sep 2025 | Viewed by 126 | Submission Open

Keywords: radiation exposure; molecular pathways; inflammation; immune response; biochemical markers; electromagnetic hypersensitivity

(This special issue belongs to the Section Molecular Biology)

Molecular Biology of Periodontal Disease and Periodontal Pathogens

edited by Yago Leira and

João Botelho

submission deadline 30 Sep 2025 | Viewed by 126 | Submission Open

Keywords: periodontitis; general medicine; inflammation; bacteraemia; education

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Drug-Induced Toxicity and Its Role in Disease Progression and Therapeutic Outcomes

edited by

Eugenia Gallardo

and

Tiago Rosado

submission deadline 30 Sep 2025 | Viewed by 125 | Submission Open

Keywords: drug-induced toxicity; drug-drug interactions; drug delivery systems; toxicity; disease

(This special issue belongs to the Section Molecular Toxicology)

Hemolytic Anemia: From Molecular Mechanisms to Therapeutic Exploitation

edited by Joan-Lluis Vives-Corrons

submission deadline 30 Sep 2025 | Viewed by 124 | Submission Open

Keywords: hemolytic anemias; red blood cells; sickle cell disease; targeted therapies; precision medicine

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Studies in Gynecological Oncology: Advancing Diagnosis and Treatment

edited by

Ivonne Nel

submission deadline 30 Sep 2025 | Viewed by 124 | Submission Open

Keywords: biomarker; cancer screening; clinical trial; DNA repair; invasion; metastasis; methylation; molecular diagnostics; molecular tumor pathology; next-generation sequencing; omics; personalized medicine; prognosis; single-cell analysis; targeted therapy; translational cancer research; treatment response; tumor microenvironment

(This special issue belongs to the Section Molecular Oncology)

Multifunctional Nano-Coatings for Biomedical Applications

edited by

Mikhail Kryuchkov

and Jana Valnohova

submission deadline 30 Sep 2025 | Viewed by 119 | Submission Open

Keywords: nanocoatings; nanomedicine; drug delivery; surface functionalization; diagnostics; therapeutics; prevention; stimuli-responsive materials; biomedical nanotechnology; targeted delivery systems; biocompatible coatings

(This special issue belongs to the Section Molecular Nanoscience)

Drug Development and Discovery for Alzheimer's Disease

edited by Martha Cecilia Rosales-Hernández

submission deadline 30 Sep 2025 | Viewed by 119 | Submission Open

Keywords: Alzheimer's disease; drug design; repurposed molecules; therapeutic targets; amyloid-β ; β -secretase; acetylcholin-esterase; in silico studies; oxidative stress; chemical synthesis

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Insights into Probiotics and Prebiotics in Gut Health and Disease

edited by

Hikmate Abriouel

submission deadline 30 Sep 2025 | Viewed by 114 | Submission Open

Keywords: probiotics; prebiotics; gut microbiota; intestinal health; dysbiosis; host– microbe interactions; omics; gut– brain axis

(This special issue belongs to the Section Molecular Microbiology)

Molecular Research and Insights into COVID-19: Third Edition

edited by

Manuela Rizzi

and

Pier Paolo Sainaghi

submission deadline 30 Sep 2025 | Viewed by 113 | Submission Open

Keywords: SARS-CoV-2; COVID-19; prognostic and diagnostic biomarkers; molecular mechanism of infection; molecular pathophysiology; immune response

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Metallopharmaceuticals: Current Trends and Future Perspectives in Cancer Immunoediting

edited by

Marialuisa Piccolo

and

Claudia Riccardi

submission deadline 30 Sep 2025 | Viewed by 113 | Submission Open

Keywords: metal-based drugs; anticancer activity; mechanisms of action; tumor microenvironment; immune cell regulation; cancer immunity; metal– protein interactions; metal– nucleic acid interactions

(This special issue belongs to the Section Molecular Pharmacology)

The New Developments in Third-Generation Sequencing Methods in Human Rare Diseases

edited by

Rick Kamps

submission deadline 30 Sep 2025 | Viewed by 113 | Submission Open

Keywords: short-read sequencing; long-read sequencing; single-cell rna sequencing; spatial-transcriptomic sequencing; single-nucleotide sequencing; structural-variant sequencing; protein-omics sequencing

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Colorectal Cancers: New Approach to Their Pathology, Diagnosis and Therapy

edited by

Mariusz Chabowski

submission deadline 30 Sep 2025 | Viewed by 111 | Submission Open

Keywords: occult blood test; colorectal cancer; colonoscopy; rectal bleeding; abdominal pain; hemicolectomy; novel oncological drugs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Exploring Therapeutic Targets in the Evolving Landscape of Cancer Immunotherapy: 2nd Edition

edited by

Domenico Galati

submission deadline 30 Sep 2025 | Viewed by 111 | Submission Open

Keywords: immune checkpoints; targeted therapies; tumor microenvironment; cancer immunology; precision medicine; cell-based cancer therapy

(This special issue belongs to the Section Molecular Immunology)

Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors (Third Edition)

edited by

Rima Dardik

and

Tami Livnat

submission deadline 30 Sep 2025 | Viewed by 111 | Submission Open

Keywords: procoagulant factors; anticoagulant factors; hemostasis; inflammation; genetics; therapeutics; cell signaling

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oral Microbiota in Health and Disease: Novel Insights and Therapeutic Approaches

edited by

Biagio Rapone

submission deadline 30 Sep 2025 | Viewed by 110 | Submission Open

Keywords: oral microbiome; periodontal health and disease; host-microbiome interactions; oral pathogens; antimicrobial strategies; probiotics; prebiotics; postbiotics; ioactive metabolites; immunocompromised

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment—2nd Edition

edited by

Morris Karmazyn

submission deadline 30 Sep 2025 | Viewed by 110 | Submission Open

Keywords: cardiac hypertrophy; myocardial remodelling; heart failure; cellular mechanisms; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Horizons in Pain Therapeutics

edited by Alaa Abd-Elsayed

submission deadline 30 Sep 2025 | Viewed by 110 | Submission Open

Keywords: spinal cord stimulation; peripheral nerve stimulation; stem cell therapy; platelet-rich plasma (PRP) injections; chronic pain management; interventional pain procedure

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Application of NMR Spectroscopy in Biomolecules: 2nd Edition

edited by

Luigi Russo

submission deadline 30 Sep 2025 | Viewed by 109 | Submission Open

Keywords: advanced solution and solid state biomolecular NMR techniques; structure and dynamics of biomolecules: proteins; peptides; and nucleic acids; paramagnetic NMR; in/on cell-NMR; protein– ligand; protein– DNA; protein– RNA interaction; protein folding and misfolding; structure-based drug screening; fragment-based drug screening; computational NMR methods; sample preparation and isotope labeling strategies; NMR metabolomics and foodomics; membrane proteins and lipids; natural-abundance NMR spectroscopy; pharmaceutical NMR applications; disordered proteins and peptides; drugs development; metal-binding biomolecules; hyperpolized NMR techniques; 19F NMR spectroscopy; NMR techniques for the analysis of complex mixtures; integrated NMR-based methodologies

(This special issue belongs to the Section Molecular Biophysics)

Molecular Mechanisms of Antiviral Agents and Antiviral Therapy

edited by

Jesus Alberto Silvas

submission deadline 30 Sep 2025 | Viewed by 109 | Submission Open

Keywords: therapeutics; high-throughput screening; viral reverse genetics; luciferase; fluorescent; compound; repurpose; antiviral; diagnostics

(This special issue belongs to the Section Molecular Immunology)

Latest Molecular Advances in Prostate Cancer

edited by Rejane Maira Góes

submission deadline 30 Sep 2025 | Viewed by 107 | Submission Open

Keywords: prostate cancer; androgen signaling; metabolic reprogramming; tumor microenvironment; inflammation; immunotherapy; chemoprotection; phytotherapy

(This special issue belongs to the Section Molecular Oncology)

Dialogue Between Inflammation and Immunity: From Mechanism to Therapy

edited by

Nikolina Mihaylova

submission deadline 30 Sep 2025 | Viewed by 106 | Submission Open

Keywords: inflammation; immune activation; immunomodulation; tolerance; immunotherapy; autoimmune diseases; cancer

(This special issue belongs to the Section Molecular Immunology)

Recent Molecular Research in Colitis

edited by

Pablo García-Miranda

and

María Vázquez-Carretero

submission deadline 30 Sep 2025 | Viewed by 106 | Submission Open

Keywords: colitis; inflammatory bowel disease (IBD); gut-brain axis; intestinal barrier; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Intercellular Adhesion and Inflammatory Response in Cancer

edited by Anna Pryczynicz

submission deadline 30 Sep 2025 | Viewed by 105 | Submission Open

Keywords: adhesion; cancer; cancer therapy; inflammation; microenvironment

(This special issue belongs to the Section Molecular Biology)

Genetics and Omics in Autoimmune Diseases

edited by

Julian Ramírez-Bello

submission deadline 30 Sep 2025 | Viewed by 104 | Submission Open

Keywords: autoimmune diseases; genetics; genomics; omics; single-nucleotide variants; copy number variants; variation; susceptibility; mRNAs; microRNAs; long non-coding RNAs; masive sequencing

(This special issue belongs to the Section Molecular Genetics and Genomics)

Novel Genotypes and Experimental Advances in Xenotransplantation

edited by Konrad Fischer

submission deadline 30 Sep 2025 | Viewed by 103 | Submission Open

Keywords: xenotransplantation; genetic engineering; preclinical models; genetically modified donor organs

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Pesticide Exposure and Toxicity Research: Impacts on Endocrine and Nervous System Pathophysiology

edited by

Jorgelina Varayoud

submission deadline 30 Sep 2025 | Viewed by 103 | Submission Open

Keywords: pesticide exposure; neurotoxicity; endocrine disruption; risk assessment; toxicological mechanisms; human health effects; biomonitoring; animal models

(This special issue belongs to the Section Molecular Toxicology)

Bioactive Phenolics and Polyphenols 2025

edited by

Davide Barreca

submission deadline 30 Sep 2025 | Viewed by 102 | Submission Open

Keywords: phenolic metabolism; biological activities; stability to food processing; elicitation; methods of analysis; dietary supplements; nutraceutical ingredients; non-thermal processing; extraction and purification

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Displaying special issue 951-1000 on page 20 of 68.

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