Dynamics of Fascia: Cellular, Molecular, and Biochemical Mechanisms
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 31 March 2026 | Viewed by 8
Special Issue Editor
Interests: fascia; pain; extracellular matrix; hyaluronan; collagen; sex hormones; aging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Fascia, long regarded as passive connective tissue merely supporting muscles and organs, is increasingly appreciated as a dynamic and responsive system fundamental for tissue homeostasis, mechanobiology, and intercellular communication. This Special Issue aims to explore the cellular, molecular, and biochemical mechanisms governing fascial dynamics in both physiological and pathological contexts. Particular attention will be given to how fibroblasts, myofibroblasts, and other resident cells transduce mechanical and biochemical cues to maintain tissue homeostasis and respond to stress or injury.
Furthermore, the role of fascia in chronic pain syndromes, inflammation, hormonal balance, and the modulation of connective tissue function represents an emerging and clinically relevant field. Studies investigating biochemical and neuroendocrine interactions within fascial tissues, and how these processes contribute to etiology of pain, are especially welcome. By integrating basic and translational research, this Special Issue aims to provide a comprehensive understanding of fascial biology and its implications for health, disease, and therapeutic innovation.
Dr. Caterina Fede
Guest Editor
Manuscript Submission Information
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Keywords
- fascia
- homeostasis and pathology
- extracellular matrix remodeling
- fibroblast signaling
- chronic pain
- fibrosis and inflammation
- hormonal regulation
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