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Recent Advances in Nanotechnology for Biomedical Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 987

Special Issue Editor


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Guest Editor
Departamento de Ciencias Químicas, Facultad de Farmacia y Bioquímica, Cátedra de Química Analítica Instrumental, Universidad de Buenos Aires, Buenos Aires 1113, Argentina
Interests: nanotechnology; regenerative medicine; medicinal chemistry

Special Issue Information

Dear Colleagues,

Recent advances in nanotechnology have significantly improved biomedical applications, offering innovative solutions for disease diagnosis and treatment. Nanomaterials can deliver drugs directly to targeted sites, increasing treatment efficiency while reducing side effects. This targeted drug delivery is particularly useful in cancer therapy, where precision is crucial. In addition, nanosensors are being developed to detect diseases at very early stages by identifying tiny amounts of biological markers in the body. Nanotechnology also plays an important role in regenerative medicine, helping scientists design better materials for tissue engineering and cell repair. Furthermore, antimicrobial nanocoatings are used on medical devices and implants to prevent infections and improve patient safety. Overall, recent developments in nanotechnology are transforming modern medicine by enabling more accurate diagnostics, personalized treatments, and improved therapeutic outcomes for patients around the world.

Dr. Sofía Municoy
Guest Editor

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Keywords

  • nanotechnology
  • nanosensor
  • drug delivery
  • regenerative medicine

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Published Papers (1 paper)

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Research

16 pages, 8780 KB  
Article
Phytochemistry-Guided Green Synthesis of Antimicrobial Silver Nanoparticles from Cannabis sativa Chemovars
by Fresia M. Silva Sofrás, Sofia Municoy, Jimena Guajardo, Pablo E. Antezana, Nicolás Nagahama, Mariano Cáceres, Pablo L. Santo-Orihuela and Martín F. Desimone
Int. J. Mol. Sci. 2026, 27(9), 3713; https://doi.org/10.3390/ijms27093713 - 22 Apr 2026
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Abstract
The phytochemical variability in Cannabis sativa L. chemovars represents an underexplored factor in environmentally sustainable nanomaterial production. In this study, three distinct chemovars, (i) High-Δ9-Tetrahydrocannabinol (THC) (89% THC), (ii) Balanced (60% Cannabidiol (CBD)), and (iii) High-CBD (89% CBD), were comparatively evaluated [...] Read more.
The phytochemical variability in Cannabis sativa L. chemovars represents an underexplored factor in environmentally sustainable nanomaterial production. In this study, three distinct chemovars, (i) High-Δ9-Tetrahydrocannabinol (THC) (89% THC), (ii) Balanced (60% Cannabidiol (CBD)), and (iii) High-CBD (89% CBD), were comparatively evaluated to determine their suitability for the green synthesis of silver nanoparticles (AgNPs). Ethanolic inflorescence extracts were used to recover bioactive secondary metabolites; among them, the High-CBD extract exhibited the highest total phenolic (3.34 mg gallic acid equivalent/g) and flavonoid (29.49 mg quercetine equivalent/g) contents, together with superior antioxidant capacity (53.16% 2,2-diphenyl-1-picrylhydrazyl free radical (DPPH) inhibition), indicating enhanced redox potential for nanoparticle formation. The terpene profile of High-CBD showed a dominance of myrcene (21.4%), contributing to the stabilization of the system. Using the High-CBD extract, predominantly spherical nanoparticles of 5 ± 0.9 nm were synthesized and confirmed by UV–vis, EDS, and TEM. The biogenic AgNPs demonstrated significant dose-dependent antibacterial activity, with minimum bactericidal concentration (MBC) of 1.0 mg/mL against Staphylococcus aureus and 4.5 mg/mL against Escherichia coli. These findings highlight the critical role of chemovar-dependent phytochemical composition and support a phytochemistry-guided approach for developing silver nanoparticles with potential biomedical applications. Full article
(This article belongs to the Special Issue Recent Advances in Nanotechnology for Biomedical Applications)
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