Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors (Third Edition)
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 1947
Special Issue Editors
Interests: procoagulant factors; anticoagulant factors; hemostasis
Special Issues, Collections and Topics in MDPI journals
Interests: procoagulant factors; anticoagulant factors; hemostasis; neuroprotection; ocular diseases
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This is a continuation of the series on the hot topic of the “Genetic, Functional and Therapeutic Aspects of Procoagulant and Anticoagulant Factors”; our 1st and 2nd editions of Special Issue on this topic received interesting contributions and discussions.
https://www.mdpi.com/journal/ijms/special_issues/Anticoagulant_Factors
https://www.mdpi.com/journal/ijms/special_issues/Pro_Anticoagulant
Normal hemostasis is highly dependent on the balance between procoagulant systems (e.g., platelets and procoagulant factors) and anticoagulant systems (e.g., protein C, protein S and antithrombin). The lack or dysfunction of a major procoagulant factor results in a bleeding disorder (e.g., factor VIII deficiency leading to hemophilia A), whereas a defect in an essential anticoagulant system (e.g., protein C deficiency) leads to a thrombotic disorder. Beyond their function in hemostasis, cell signaling pathways that are induced by procoagulant (e.g., thrombin and FVII) and anticoagulant factors (e.g., APC), mediated by specific receptors, have become the focus of increasing attention, with some of them being explored as promising therapeutic targets.
This Special Issue will focus on the genetic, functional and therapeutic aspects of procoagulant and anticoagulant systems. We invite research studies and reviews on the genetics of bleeding and thrombotic disorders and functional and therapeutic studies of procoagulant and anticoagulant factors, as well as studies that explore their involvement in the crosstalk between hemostasis and inflammation.
Dr. Rima Dardik
Prof. Tami Livnat
Guest Editors
Manuscript Submission Information
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Keywords
- procoagulant factors
- anticoagulant factors
- hemostasis
- inflammation
- genetics
- therapeutics
- cell signaling
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