The Interaction Between Cell and Virus, 3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 20 April 2026 | Viewed by 707
Special Issue Editor
Interests: Kaposi’s sarcoma-associated herpesvirus post-translational modification proteasome ubiquitin virus
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue follows the publication of the first edition on “The Interaction Between Cell and Virus” (https://www.mdpi.com/journal/ijms/special_issues/Interaction_Cell_and_Virus)” and “The Interaction Between Cell and Virus, 2nd Edition” (https://www.mdpi.com/journal/ijms/special_issues/R9T3G1HP37)”.
Viral infections cause various diseases in host species. Antiviral medications can help relieve the symptoms of some viruses by inhibiting viral enzymes or virus-mediated events. However, over the past half century, very few antiviral drugs (excluding anti-HCV drugs) have been developed for use in the treatment of serious and life-threatening viral infections.
A fundamental step for the effective infection and replication of all viruses is the interaction between cells and the virus. This is achieved through the dysregulation and exploitation of host cell functions (e.g., gene expression, signal transduction, metabolic process, intracellular transport, organelle biogenesis or communication, apoptosis, protein degradation, and immune response) by viral molecules, such as viral proteins and microRNA. Viruses hijack the appropriate cellular functions for the establishment of infection, persistent infection, prolonging survival, the control of cell proliferation, anti-apoptosis, and the evasion of immune surveillance in infected cells. Viruses manipulate these cellular functions in order to create a favorable environment for the virus or the virus-infected cell. However, the host species exerts antiviral effects on virus infection through the interaction between cells and the virus.
A better understanding of the interaction between viruses and host cells could provide new insights into the process of pathogenesis, immune disruption (or activation), and tumorigenesis triggered by viruses and may provide a theoretical basis for the development of novel therapeutic interventions against infectious diseases.
For this Special Issue, original research articles, review articles and short communications are welcome. Research areas of interest include the cell–virus interaction involved in viral replication, gene expression, latent or lytic infection, viral structural proteins and enzymes, virus assembly, cell signaling pathways, post-translational modification, host factors, virus immune evasion, host immune response, viral tumorigenesis or disease, antiviral medication, vaccine, animal models, and gene therapy.
Prof. Dr. Masahiro Fujimuro
Guest Editor
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Keywords
- viral replication
- gene expression
- lytic infection
- viral structure
- viral assembly
- cell signaling pathway
- post-translational modification
- immune evasion
- viral tumorigenesis
- antiviral medication
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