Molecular Diagnostics in Cardiovascular Diseases: From Biomarkers to Personalized Medicine

Dear Colleagues,

Cardiovascular diseases (CVDs) remain the leading cause of death globally, highlighting the urgent need for innovative diagnostic tools that enable early detection, risk stratification, and personalized therapy. This Special Issue aims to explore the evolving role of molecular diagnostics in transforming cardiovascular care, from traditional biomarkers to advanced genomic, proteomic, and metabolomic technologies. As precision medicine becomes an integral part of clinical practice, identifying and validating reliable molecular markers is critical to guiding targeted interventions and improving outcomes.

We invite original research articles and reviews focused on the discovery, validation, and clinical application of molecular diagnostics in cardiovascular settings. Topics of interest include, but are not limited to, the following: circulating biomarkers (e.g., troponins, natriuretic peptides, sST2, and galectin-3), genetic and epigenetic profiling, RNA-based diagnostics, multi-omics integration, liquid biopsy approaches, biomarker-guided therapy, and the use of artificial intelligence in biomarker discovery and risk prediction. Studies addressing molecular diagnostics in specific conditions such as heart failure, coronary artery disease, myocarditis, and cardiomyopathies are especially welcome. This Special Issue seeks to provide a comprehensive overview of the current landscape and future directions in molecular diagnostics for CVDs, with an emphasis on translational relevance and clinical impact.

Dr. Otilia Țica
Guest Editor

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