Diagnostic Imaging of Brain Disease, Second Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 479

Special Issue Editor


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Guest Editor
Department of Imaging, Radiation Therapy and Hematology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy
Interests: MRI; CT; neuroradiology; neoplasms and tumor-like lesions of the sellar region
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Special Issue Information

Dear Colleagues,

The sellar region represents a complex anatomical area, composed of multiple structures of different embryological derivation, including the skull base and the pituitary gland, along with vascular, nervous, and meningeal structures.

The aim of this Special Issue on Diagnostic Imaging of Brain Disease is to provide an overview of the common neoplasms and tumor-like conditions of the sellar region, including both those originating from the pituitary gland and those originating from the surrounding structures which secondarily invade the sellar, with an emphasis on the clinical, radiologic and pathologic findings.

Authors are invited to submit original research and reviews about the anatomy of this region, skull base and pituitary tumors, infections, and cystic or vascular lesions, focusing both on the currently used imaging modalities and on innovative MRI radiomic data, relevant for diagnosis, follow up and outcome predictions.

Topics include the following areas: clinical, neuroimaging and neurosurgical areas applied to neoplasms and tumor-like lesions of the sellar region.

Dr. Rosalinda Calandrelli
Guest Editor

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Keywords

  • adenomas
  • craniopharyngiomas
  • skull base lesions
  • infections
  • cystic lesions
  • vascular lesions
  • MRI
  • CT
  • radiomics

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Published Papers (1 paper)

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10 pages, 2624 KiB  
Case Report
A Silent Threat: Internal Carotid Artery Hypoplasia and Its Role in Basilar Artery Aneurysm Formation—A Case Study
by Paula Mežvinska, Artis Brokāns, Sergejs Pavlovičs, Matīss Dravnieks, Ardis Platkājis and Arturs Balodis
Diagnostics 2025, 15(6), 774; https://doi.org/10.3390/diagnostics15060774 - 19 Mar 2025
Viewed by 311
Abstract
Background and Clinical Significance: Hypoplasia of the internal carotid artery (ICA) is a rare vascular anomaly, with an estimated incidence of less than 0.01%. This condition can result in reduced blood flow to the anterior circulation, often compensated by collateral circulation. Radiological imaging, [...] Read more.
Background and Clinical Significance: Hypoplasia of the internal carotid artery (ICA) is a rare vascular anomaly, with an estimated incidence of less than 0.01%. This condition can result in reduced blood flow to the anterior circulation, often compensated by collateral circulation. Radiological imaging, particularly computed tomography angiography (CTA), digital subtraction angiography (DSA), magnetic resonance angiography (MRA), and ultrasound, plays a crucial role in diagnosing this condition, revealing structural abnormalities in the arterial system. Case Presentation: This case is about a 75-year-old woman who lived her entire life unaware of ICAH until a basilar artery aneurysm ruptured, leading to a large, centrally localized SAH. Further diagnostic workup, including CTA and DSA, confirmed left ICA hypoplasia, with the artery terminating as the ophthalmic artery, along with a developmental anomaly of the left middle cerebral artery from posterior circulation territory. Due to the high risk associated with surgical and endovascular intervention, conservative management was pursued, and the patient’s condition stabilized, though she continued to have significant neurological deficits. Conclusions: This case report supports the hypothesis that ICAH may be associated with aneurysm formation. This case demonstrates that if ICAH is not diagnosed early, it can lead to severe complications with permanent neurological deficits. Additionally, it highlights the critical importance of advanced imaging techniques, such as CTA and DSA, in diagnosing complex vascular conditions. Full article
(This article belongs to the Special Issue Diagnostic Imaging of Brain Disease, Second Edition)
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