Cardiometabolic Disease: Diagnosis and Management

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Clinical Laboratory Medicine".

Deadline for manuscript submissions: closed (30 September 2025) | Viewed by 655

Special Issue Editor


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Guest Editor
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA
Interests: cardiology; myocardial infarctions; heart failure; cardiovascular interventions

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the intricate relationship between cardiovascular diseases and metabolic disorders, such as diabetes and obesity. It explores innovative diagnostic techniques, biomarkers, and imaging technologies that enhance early detection and treatment strategies. This Special Issue highlights the importance of multidisciplinary approaches in improving clinical outcomes, emphasizing lifestyle interventions, and emerging treatments. Moreover, it addresses health disparities and the need for personalized medicine in managing cardiometabolic conditions, ensuring that diverse populations receive tailored care. Together, the articles provide valuable insights into the complexities of managing these intertwined diseases and advocate for comprehensive strategies to reduce their prevalence and impact on public health.

Dr. Muhammad Shariq Usman
Guest Editor

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Keywords

  • cardiometabolic disease
  • diagnosis
  • management
  • diabetes
  • obesity
  • personalized medicine

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Published Papers (1 paper)

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Research

14 pages, 510 KB  
Article
Interplay of Modifiable and Non-Modifiable Risk Factors for Diabetes Mellitus in Saudi Adults
by Mohammad A. Jareebi and Ibrahim M. Gosadi
Diagnostics 2025, 15(19), 2451; https://doi.org/10.3390/diagnostics15192451 - 25 Sep 2025
Viewed by 469
Abstract
Background/Objectives: Diabetes Mellitus (DM) remains a critical public health issue in Saudi Arabia, shaped by complex interactions among genetic, lifestyle, and sociodemographic factors. This study explores interplay of modifiable and non-modifiable determinants of DM among Saudi adults. Methods: An analytical cross-sectional study was [...] Read more.
Background/Objectives: Diabetes Mellitus (DM) remains a critical public health issue in Saudi Arabia, shaped by complex interactions among genetic, lifestyle, and sociodemographic factors. This study explores interplay of modifiable and non-modifiable determinants of DM among Saudi adults. Methods: An analytical cross-sectional study was conducted among 3411 adults aged 18 years and above in the Jazan region, southwest of Saudi Arabia, in May–June 2024. Data was collected via a structured, pretested questionnaire assessing sociodemographic, dietary patterns, physical activity, smoking habits, and family history of DM. Bivariate analysis and logistic regression were used to identify associations with self-reported diabetes. Results: Out of 3411 participants (1735 males and 1676 females), 424 (12.4%) reported DM. Diabetics were older (48 vs. 32 years), more often male, married, had lower education, had larger families, had higher BMIs, and exhibited more tobacco use (p < 0.05), and a family history of diabetes was strongly associated with diagnosis of DM (p < 0.001). Diabetics were more likely to choose low-fat meats, avoid sugary foods, and select low-fat products (p < 0.05). In multivariate analysis, predictors were age (OR = 1.07, 95% CI: 1.06–1.09), male sex (OR = 1.65, 95% CI: 1.26–2.16), family history (OR = 7.68, 95% CI: 5.67–10.57), traditional housing (OR = 1.82, 95% CI: 1.11–3.05), and whole grain intake (OR = 0.67, 95% CI: 0.52–0.85). Conclusions: DM in Saudi Arabia is driven by both inherited and behavioral risks. These findings support the urgent need for integrated, culturally tailored prevention strategies that combine early screening for individuals with higher risk. Targeted actions such as relevant lifestyle interventions can help reduce disease burden and align with Saudi Vision 2030 health priorities. Full article
(This article belongs to the Special Issue Cardiometabolic Disease: Diagnosis and Management)
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