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Diagnostics
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Editorial Board Members' Collection Series: Molecular Diagnostics of Infectious Diseases,...
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Editorial Board Members' Collection Series: Molecular Diagnostics of Infectious Diseases, 2nd Edition

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Diagnostic Microbiology and Infectious Disease".

Deadline for manuscript submissions: 31 May 2026 | Viewed by 509

Special Issue Editors

Dr. Thierry Naas

E-Mail Website
Guest Editor
School of Medicine, University Paris Saclay, Hopital de Bicêtre, Service de Bactériologie, Bâtiment Broca, 3ème étage, 78 rue du Gal Leclerc, 94275 Le Kremlin-Bicêtre, France
Interests: genetics of antibiotic resistance; gram negatives; ß-lactamases; carbapenemases; diagnostics (biochemical, phenotypical, molecular) and diagnostics of antibiotics resistance genes; NGS; transcriptomics; microbiota
Special Issues, Collections and Topics in MDPI journals
Dr. Ranjan Ramasamy

E-Mail Website
Guest Editor
IDFISH Technology, 556 Gibraltar Drive, Milpitas, CA 95035, USA
Interests: immunodiagnostics; molecular diagnostics; vector-borne diseases; immunology and biochemistry
Special Issues, Collections and Topics in MDPI journals
Dr. Ilana Lopes Baratella da Cunha Camargo

E-Mail Website
Guest Editor
Laboratório de Epidemiologia e Microbiologia Moleculares—LEMiMo, Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos 13563-120, SP, Brazil
Interests: mechanisms of antimicrobial resistance; epidemiology of resistant bacteria; search for new antimicrobial compounds
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue focuses on the application of molecular diagnostics in infectious diseases. We aim for it to provide an in-depth analysis of the latest research and clinical practices using molecular techniques to detect and identify microorganisms causing infectious diseases. We welcome articles that discuss the potential of molecular diagnostics in areas such as virus detection, antibiotic resistance profiling, and the genotyping of bacterial strains. We hope that this Special Issue will assist infectious disease professionals in understanding and utilizing molecular diagnostics to optimize patient care and infection control.

Dr. Thierry Naas
Dr. Ranjan Ramasamy
Dr. Ilana Lopes Baratella da Cunha Camargo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular diagnostics
  • infectious diseases
  • microorganisms
  • virus detection
  • antibiotic resistance
  • bacterial strains

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Related Special Issue

Published Papers (1 paper)

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Research

12 pages, 554 KB  
Article
Impact of FilmArray Gastrointestinal Panel Compared to Standard-of-Care Diagnostic Tests in Clinical Practice of Acute Gastroenteritis in an HIV Reference Center with Limited Resources
by Guilherme Alves de Lima Henn, Marina Farrel Côrtes, Pedro Pinheiro de Negreiros Bessa, Francisco Breno Ponte de Matos, Jacqueline Sousa and Juliana Festa Ortega
Diagnostics 2026, 16(1), 121; https://doi.org/10.3390/diagnostics16010121 - 1 Jan 2026
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Abstract
Background/Objectives: Gastroenteritis remains a major global health concern, particularly in resource-limited regions, where rapid and accurate diagnosis is crucial for effective patient management. Syndromic multiplex PCR panels, such as the FilmArray gastrointestinal (FAGI) panel, offer the potential to significantly improve diagnostic yield and [...] Read more.
Background/Objectives: Gastroenteritis remains a major global health concern, particularly in resource-limited regions, where rapid and accurate diagnosis is crucial for effective patient management. Syndromic multiplex PCR panels, such as the FilmArray gastrointestinal (FAGI) panel, offer the potential to significantly improve diagnostic yield and turnaround time, enabling more targeted treatments and reducing unnecessary antibiotic use. However, real-world data on their performance in low-resource settings remains scarce. This study evaluates the performance, clinical impact, and cost-effectiveness of the FAGI panel compared to standard of care (SOC) diagnostic methods in gastroenteritis cases at São José Hospital for Infectious Diseases in Fortaleza, Brazil, an HIV Reference Center, in a resource-limited region of a middle-income country. Methods: A retrospective observational study was conducted among patients tested with FAGI (n = 161) and a retrospective control group tested only with SOC methods (n = 166). Results: The FAGI panel was associated with a significant reduction in the turnaround time, antimicrobial use, and total treatment costs while increasing the pathogen detection rate. Specifically, the median diagnostic time was reduced by 18%, with an increase in pathogen detection compared to SOC methods (64% positivity compared to 32%). Moreover, the FAGI group experienced a 30% reduction in antibiotic use, with a corresponding 83% reduction in antimicrobial costs. Conclusions: These results suggest that the FilmArray panel may offer substantial benefits in terms of efficiency and cost savings, highlighting its potential for broader implementation in clinical practice, especially in resource-limited settings, to improve patient outcomes in infectious disease management. Full article
(This article belongs to the Special Issue Editorial Board Members' Collection Series: Molecular Diagnostics of Infectious Diseases, 2nd Edition)
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