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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in the Diagnosis and Management of Chronic Disease

edited by

Lin Zhang

submission deadline 30 Apr 2026 | Viewed by 309 | Submission Open

Keywords: biomarkers; digital health technologies; artificial intelligence in diagnostics; non-invasive imaging; genomic screening; point-of-care testing; risk stratification models; multi-omics integration

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Integrated Point-of-Care Testing (POCT) Systems: Recent Progress and Applications

edited by Kim Wolff

submission deadline 30 Apr 2026 | Viewed by 297 | Submission Open

Keywords: point-of-care testing (POCT); integrated diagnostic systems; nano-diagnostics; artificial intelligence (AI); clinical decision support; multi-biomarker panels; electronic health records (EHRs) connectivity; infectious disease diagnostics; decentralized healthcare

(This special issue belongs to the Section Point-of-Care Diagnostics and Devices)

Pathogenesis, Diagnosis, and Management of Rheumatic Disease: Progress and Challenges

edited by Miguel Ángel González-Gay

submission deadline 30 Apr 2026 | Viewed by 296 | Submission Open

Keywords: rheumatic disease; systemic vasculitis; rheumatoid arthritis; metabolic syndrome; atherosclerosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Operational Neurosurgery: Clinical Features, Diagnosis and Prognosis

edited by Xiaoyu Yang and Mark Wilson

submission deadline 30 Apr 2026 | Viewed by 279 | Submission Open

Keywords: cranial; spinel; peripheral nerve; pediatric; pre-operative evaluation; risk stratification; prognostic models; patient-reported outcomes; peri-operative pathways; equity; AI

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Imaging in Heart Failure: Advances, Applications, and Future Directions

edited by

Attila Frigy

submission deadline 30 Apr 2026 | Viewed by 248 | Submission Open

Keywords: heart failure; echocardiography; cardiovascular magnetic resonance (CMR); computed tomography (CT); nuclear imaging (PET/SPECT); prognosis

(This special issue belongs to the Section Medical Imaging and Theranostics)

Application of Robotics in Disease Diagnosis and Management

edited by Michele Tedeschi

submission deadline 30 Apr 2026 | Viewed by 231 | Submission Open

Keywords: robotic surgery; disease diagnosis; disease management; outcomes; robotic systems

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Precision Medicine for Prostate Cancer: From Molecular Imaging to Targeted Diagnosis and Therapy

edited by

Kalevi Kairemo

and

Finn Edler von Eyben

submission deadline 30 Apr 2026 | Viewed by 231 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; PSMA; prostate cancer

(This special issue belongs to the Section Medical Imaging and Theranostics)

Emerging Imaging Techniques in Reconstructive Microsurgery

edited by Marios N. Papadakis

submission deadline 30 Apr 2026 | Viewed by 212 | Submission Open

Keywords: reconstructive microsurgery; intraoperative imaging; indocyanine green angiography; high-resolution ultrasound; 3D imaging; magnetic resonance imaging (MRI); perfusion monitoring; imaging-guided surgery; dynamic thermography; surgical planning tools

(This special issue belongs to the Section Medical Imaging and Theranostics)

Precision Diagnosis and Treatment of Chorioretinal Diseases: From Biomarkers to Imaging

edited by

Jay Kumar Chhablani

submission deadline 30 Apr 2026 | Viewed by 211 | Submission Open

Keywords: ocular imaging; biomarkers; retinal imaging; retinal diseases

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Ovarian Cancer in 2025–2026: A Comprehensive Look at Characteristics, Screening, Diagnosis and Treatment

edited by

Edward J. Pavlik

submission deadline 1 May 2026 | 2 articles | Viewed by 7735 | Submission Open

Keywords: ovarian cancer; risk; treatment; detection; screening; trial design; treatment; collateral effects; endpoints; costs; efficacy; AI; sojourn time models; vaccines; PARP inhibitors; liquid biopsies; post treatment hematologic malignancies; HIPEC; STIC/STIL

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Thyroid Disorders: New Clinical Diagnosis and Management

edited by

Ioannis P. Iakovou

Rodis D. Paparodis

and

Nicholaos G. Angelopoulos

submission deadline 15 May 2026 | Viewed by 262 | Submission Open

Keywords: thyroid disorders; clinical diagnosis; ultrasound; elastography; thyroid cancer; thyroiditis; hyperthyroidism; hypothyroidism; advanced imaging

Advances in Nephrology

edited by

Marijn M. Speeckaert

submission deadline 30 May 2026 | 9 articles | Viewed by 47526 | Submission Open

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Diagnostic and Therapeutic Strategies for Infectious Diseases

edited by

Margherita Sambo

submission deadline 31 May 2026 | 7 articles | Viewed by 22167 | Submission Open

Keywords: infectious diseases; diagnostic advancements; therapeutic strategies; antimicrobial resistance; molecular diagnostics; clinical management; emerging pathogens; precision medicine

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Diagnosis and Management of Ophthalmic Disorders

edited by Assaf Kratz

submission deadline 31 May 2026 | 11 articles | Viewed by 14430 | Submission Open

Keywords: ocular diseases; early diagnosis; advanced imaging; glaucoma; age-related macular degeneration; diabetic retinopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Medical Imaging in Diagnosis, Prevention and Rehabilitation of Musculoskeletal Injuries

edited by

Yih-Kuen Jan

, W. Catherine Cheung and Suguna Pappu

submission deadline 31 May 2026 | 4 articles | Viewed by 10167 | Submission Open

Keywords: fitting of prostheses and exoskeletons; force-based manipulations; medical imaging (e.g.; MRI; CT; ultrasound elastography); musculoskeletal pain (low-back pain and non-specific causes of chronic pain); myofascial pain syndrome; sports training; surgical scar and postoperative management; thermal and non-thermal modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

Liquid Biopsy: Cancer Diagnostic Biomarkers of the Future

edited by

Dario Marchetti

submission deadline 31 May 2026 | 4 articles | Viewed by 9440 | Submission Open

Keywords: liquid biopsy; circulating tumor cells (CTCs); ctDNA testing; exosomes; blood analytes

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advanced Diagnostic Approaches in Cardiovascular Diseases: From Imaging to Biomarkers

edited by

Ovidiu Mitu

and

Lucia Stefania Magda

submission deadline 31 May 2026 | 9 articles | Viewed by 9093 | Submission Open

Keywords: medical diagnosis; cardiovascular diseases; imaging; biomarkers; AI-driven analytics

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

DNA Sequencing of Infectious Diseases

edited by

Edward R. B. Moore

and

Daniel Jaén Luchoro

submission deadline 31 May 2026 | 4 articles | Viewed by 8495 | Submission Open

Keywords: DNA sequencing; infectious disease; diagnostics; screening; whole-genome sequencing; targeted amplicon sequencing

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Endoscopic Diagnostics for Pancreatobiliary Disorders 2025

edited by

Masataka Kikuyama

submission deadline 31 May 2026 | 4 articles | Viewed by 7714 | Submission Open

Keywords: endoscopic ultrasonography; endoscopic retrograde cholangiopancreatography; EUS– FNA; SPACE; pancreatic cancer; bile duct caner; gallbladder cancer

(This special issue belongs to the Section Biomedical Optics)

Advances in Diagnosis of Skin and Superficial Tissues Disorders—“Old and Emerging” Diagnostic Tools—2nd Edition

edited by Costantino Ricci

submission deadline 31 May 2026 | 5 articles | Viewed by 7533 | Submission Open

Keywords: melanoma; melanocytic pathology; Merkel cell carcinoma; adnexal tumors; anatomy of the skin; histology of the skin; molecular pathology; next-generation sequencing; immunohistochemistry; histology-sonography correlation; high-frequency ultrasound probes and high-level ultrasound machines; line-field confocal optical coherence tomography

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Emergency Medicine: Diagnostic Insights

edited by Ancor Sanz-Garcia and Raúl López-Izquierdo

submission deadline 31 May 2026 | 4 articles | Viewed by 6931 | Submission Open

Keywords: diagnostic tools; point-of-care testing; prehospital; emergency medicine; rapid and accurate diagnosis; imaging modalities; biomarkers; AI-driven algorithms

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis of Digestive Diseases

edited by Noriaki Manabe

submission deadline 31 May 2026 | 4 articles | Viewed by 6692 | Submission Open

Keywords: diagnosis of gastrointestinal disease; functional gastrointestinal disorders; organic diseases; personalized medicine; physiological function evaluation

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Oral and Maxillofacial Imaging

edited by

Jòzsef Piffkó

and

Agnes Janovszky

submission deadline 31 May 2026 | 4 articles | Viewed by 6583 | Submission Open

Keywords: technological advancements; diagnostic imaging; treatment planning; clinical applications; oral and maxillofacial surgery; radiology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Updates in Vascular and Endovascular Surgery: Pathology, Diagnosis and Management

edited by Ombretta Martinelli and

Antonio Marzano

submission deadline 31 May 2026 | 6 articles | Viewed by 6250 | Submission Open

Keywords: aneurysms of the aorta; aneurysms of the arch; arterial stenosis; EVAR (endovascular aneurysm repair); FEVAR (fenestrated endovascular aneurysm repair); BEVAR (branched endovascular aneurysm repair); iliac branches; varicose veins; venous insufficiency; chronic obstructive arteriopathy

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Diagnosis and Management of Cardiovascular Diseases

edited by

Corina Maria Vasile

and Xavier Iriart

submission deadline 31 May 2026 | 4 articles | Viewed by 6035 | Submission Open

Keywords: cardiovascular diseases; artificial intelligence; deep learning; machine learning; wearable devices; imaging techniques; personalized medicine; risk prediction; telemedicine; remote monitoring; ethical considerations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Musculoskeletal Disorders: Diagnosis, Management, and Rehabilitation, 2nd Edition

edited by

Antonio Stecco

submission deadline 31 May 2026 | 4 articles | Viewed by 4985 | Submission Open

Keywords: musculoskeletal disorders; pain; disability; diagnosis; interventions; rehabilitation strategies; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence Approaches for Medical Diagnostics in the USA

edited by

Jinzhong Yang

and Yao Zhao

submission deadline 31 May 2026 | 3 articles | Viewed by 4842 | Submission Open

Keywords: artificial intelligence; medical image segmentation; image registration; image quality enhancement; image artifact reduction; radiomics; image reconstruction; deep learning in diagnostics; AI-driven medical Imaging; diagnostic accuracy; diagnostic imaging innovations

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Histopathology in Cancer Diagnosis and Prognosis—2nd Edition

edited by

Christina Magkou

submission deadline 31 May 2026 | 1 articles | Viewed by 4681 | Submission Open

Keywords: cancer; precision medicine; histopathology; diagnosis; prognostic/predictive markers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in the Diagnosis and Management of Idiopathic Normal Pressure Hydrocephalus

edited by

Elisabeth Kapaki

and

Efstratios-Stylianos Pyrgelis

submission deadline 31 May 2026 | 1 articles | Viewed by 3873 | Submission Open

Keywords: idiopathic normal pressure hydrocephalus (iNPH); neurological disorder; ventricular enlargement; cerebrospinal fluid (CSF) dynamics; cognitive impairment; gait disturbance

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Ultrasound Imaging in Clinical Diagnosis

edited by

Jinbum Kang

submission deadline 31 May 2026 | 5 articles | Viewed by 3709 | Submission Open

Keywords: diagnostic ultrasound imaging and systems; doppler ultrasound techniques and applications; elastography for tissue characterization; contrast-enhanced ultrasound (CEUS); artificial intelligence in diagnostic ultrasound; point-of-care ultrasound (POCUS); ultrasound-guided interventions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Applications of CT and MRI

edited by

Francis Zarb

submission deadline 31 May 2026 | 2 articles | Viewed by 3555 | Submission Open

Keywords: CT; MRI; diagnosis; prognosis; oncology; neurology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Medical Imaging Diagnosis of Oral and Maxillofacial Diseases

edited by

Julien Issa

Marta Dyszkiewicz-Konwińska

and Erwin Berkhout

submission deadline 31 May 2026 | 4 articles | Viewed by 3380 | Submission Open

Keywords: oral radiology; digital dentistry; dental imaging; diagnosis; treatment planning

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Diagnosis and Integrated Management of Bone and Soft Tissue Tumors

edited by Tiao Lin

submission deadline 31 May 2026 | 6 articles | Viewed by 3366 | Submission Open

Keywords: musculoskeletal neoplasms; diagnostic imaging; molecular pathology; multidisciplinary treatment; personalized medicine; translational research; multidisciplinary collaboration

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Cardiometabolic Disease: Diagnosis and Management

edited by Muhammad Shariq Usman

submission deadline 31 May 2026 | 1 articles | Viewed by 3334 | Submission Open

Keywords: cardiometabolic disease; diagnosis; management; diabetes; obesity; personalized medicine

(This special issue belongs to the Section Clinical Laboratory Medicine)

Current Diagnosis and Management of Metabolic Bone Diseases

edited by Liming Xiong

submission deadline 31 May 2026 | 3 articles | Viewed by 3202 | Submission Open

Keywords: metabolic bone disease; bone turnover markers; maintenance of bone homeostasis; multiorgan– bone axis; fracture risk assessment; diabetic osteopathy; precision management

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Collaborative Robotics and Total Laboratory Automation in Clinical Diagnostics

edited by

Robert S. Ohgami

submission deadline 31 May 2026 | 2 articles | Viewed by 3106 | Submission Open

Keywords: collaborative robotics; total laboratory automation (TLA); diagnostic medicine; clinical validation ; robotic liquid handling ; digital pathology ; clinical microbiology

(This special issue belongs to the Section Clinical Laboratory Medicine)

Advances in the Use of Artificial Intelligence for the Diagnosis and Management of Hand Conditions

edited by

Ishith Seth

submission deadline 31 May 2026 | 1 articles | Viewed by 2947 | Submission Open

Keywords: artificial intelligence; machine learning; hand conditions; preoperative diagnosis; postoperative prognosis; surgical outcomes; imaging techniques

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Clinical Advances and Applications in Neuroradiology: 2nd Edition

edited by

Houman Sotoudeh

submission deadline 31 May 2026 | 2 articles | Viewed by 2896 | Submission Open

Keywords: neuroradiology; advanced imaging; susceptibility-weighted imaging (SWI); diffusion tensor imaging (DTI); functional MRI (fMRI); CT perfusion; MR perfusion; MR spectroscopy; PET; molecular imaging; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

From Data to Decisions: Deep Learning in Clinical Diagnostics

edited by Jianfu Li

submission deadline 31 May 2026 | 1 articles | Viewed by 2669 | Submission Open

Keywords: deep learning; clinical diagnostics; medical AI; diagnostic accuracy; clinical decision support; medical imaging; biomarker discovery; healthcare implementation

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence in Medical Imaging: Innovations and Diagnostic Applications

edited by

Ayman El-Baz

, Moumen Elmelegy,

Asem M. Ali

and

Ali H. Mahmoud

submission deadline 31 May 2026 | 3 articles | Viewed by 2613 | Submission Open

Keywords: medical imaging; artificial intelligence; disease diagnosis; radiomics

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

The Application of Large Language Models (LLMs) and Vision-Language Models (VLMs) in Healthcare

edited by

Shuo-Chen Chien

and

Wen-Shan Jian

submission deadline 31 May 2026 | 2 articles | Viewed by 2384 | Submission Open

Keywords: large language models (LLMs); vision-language models (VLMs); artificial intelligence in healthcare; natural language processing (NLP); clinical decision support systems; medical imaging analysis; multimodal learning; healthcare data analytics; patient-centered care; ethical AI in medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Precise Diagnosis, Classification, and Monitoring of Pulmonary Diseases

edited by

Barbara Ruaro

Paola Confalonieri

and

Francesco Salton

submission deadline 31 May 2026 | 1 articles | Viewed by 2172 | Submission Open

Keywords: lung diseases; pulmonary diseases; imaging techniques; causal biological pathways; clinical biomarkers

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Clinical and Laboratory Diagnosis of Inherited Metabolic Diseases in Children

edited by

Patryk Lipiński

submission deadline 31 May 2026 | 1 articles | Viewed by 2002 | Submission Open

Keywords: newborn screening; selective screening; inherited metabolic disease; biochemical diagnostics; biomarkers; molecular analysis; next-generation sequencing

(This special issue belongs to the Section Clinical Laboratory Medicine)

Emerging Predictive Biomarkers in Breast Cancer

edited by

Giuseppina Rosaria Rita Ricciardi

and Maria Vita Sanò

submission deadline 31 May 2026 | 1 articles | Viewed by 1882 | Submission Open

Keywords: breast cancer; HER2-positive; TNBC; ER+; HER2-negative; HER2-low; PD-L1; 18F-FES PET; hormonotherapy; immunotherapy; immune checkpoint inhibitors; liquid biopsy; circulating tumor cells; ctDNA; antibody drug conjugates; PARP inhibitors; CDK4/6 inhibitors; predictive biomarkers

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

New Advances in Diagnostic Bronchoscopy

edited by

Kassem Harris

submission deadline 31 May 2026 | 1 articles | Viewed by 1719 | Submission Open

Keywords: diagnostic bronchoscopy; advanced imaging techniques; interventional bronchoscopy; minimally invasive techniques

(This special issue belongs to the Section Biomedical Optics)

Advances in Diagnostic Options and Treatment Strategies for Neurological Disorders

edited by

Julia Koehn

and Jenny Stritzelberger

submission deadline 31 May 2026 | 3 articles | Viewed by 1673 | Submission Open

Keywords: neuroscience; diagnostic tools; point-of-care testing; prehospital care; emergency medicine; rapid and accurate diagnosis; treatment strategies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Artificial Intelligence in Biomedical Signal and Imaging Processing

edited by

Ankush D. Jamthikar

submission deadline 31 May 2026 | 1 articles | Viewed by 1533 | Submission Open

Keywords: artificial intelligence; biomedical imaging; signal processing; unsupervised learning; generative artificial intelligence; image reconstruction; image segmentation; data augmentation; physiological signal analysis; personalized medicine; artificial intelligence-driven diagnostics; self-supervised learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnostic Imaging in Ocular Surface

edited by

Nir Erdinest

and David Berkow

submission deadline 31 May 2026 | 3 articles | Viewed by 1459 | Submission Open

Keywords: ocular surface imaging; contact lens fitting; ultra-high-resolution oct; corneal topography; corneal tomography; scleral profilometry; wavefront aberrometry; in vivo confocal microscopy; artificial intelligence in eye imaging; meibomian gland imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Inflammation and Infection Imaging: 2nd Edition

edited by

Giorgio Treglia

submission deadline 31 May 2026 | 2 articles | Viewed by 1407 | Submission Open

Keywords: imaging; infection; inflammation; radiology; nuclear medicine; molecular imaging; hybrid imaging

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis and Management of Inflammatory Respiratory Diseases

edited by Kęstutis Malakauskas and

Andrius Januskevicius

submission deadline 31 May 2026 | 1 articles | Viewed by 1389 | Submission Open

Keywords: asthma; chronic obstructive pulmonary disease; inflammatory respiratory diseases; inflammation; biomarkers; respiratory diagnostics; anti-inflammatory therapy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Displaying special issue 51-100 on page 2 of 14.

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