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Diagnostics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnosis and Management of Spinal Diseases

edited by Jwo-Luen Pao

submission deadline 31 Aug 2025 | 2 articles | Viewed by 1114 | Submission Open

Keywords: spinal diseases; spinal conditions; endoscopy; artificial intelligence (AI); radiological techniques; MRI; CT scans; X-rays; management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Radiomics and Artificial Intelligence Applications in the Diagnosis of Brain Lesions

edited by

Calin G. Buzea

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1066 | Submission Open

Keywords: brain lesions; biomarker; prognosis; diagnosis; radiomics; artificial intelligence

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Advances in Mental Health Diagnosis and Screening, 2nd Edition

edited by Elaine Chapman

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1057 | Submission Open

Keywords: mental health; diagnosis; screening; marker; prognosis

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Future Concepts in Dermatologic Diagnosis

edited by Jonathan Shapiro

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1025 | Submission Open

Keywords: skin diseases; skin pathology; molecular profiling; dermatologic diagnostics

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advancements in Diagnosis of Colorectal Cancer

edited by

Piero Boraschi

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1013 | Submission Open

Keywords: colorectal cancer; metastatic disease; colorectal liver metastases; chemotherapy; surgery; therapeutic response assessment; biomarkers; tumor regression grading; computed tomography; MRI; PET; intraoperative ultrasound; multidisciplinary management

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Endoscopy in Gynecology and Gynecologic Oncology

edited by

Rudolf Lampé

submission deadline 31 Aug 2025 | 1 articles | Viewed by 958 | Submission Open

Keywords: gynecology; endoscopy; operative gynecology

(This special issue belongs to the Section Medical Imaging and Theranostics)

Clinical Advances of Diagnosis and Management in Emergency Medicine

edited by

Ho Kyung Sung

submission deadline 31 Aug 2025 | 1 articles | Viewed by 902 | Submission Open

Keywords: emergency medicine; diagnostics; medical imaging; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Subjective Experiences of Decline and Dementia Risk: Cognitive, Functional, and Emotional Predictors of Cognitive Decline

edited by Katya Numbers

submission deadline 31 Aug 2025 | 1 articles | Viewed by 873 | Submission Open

Keywords: subjective cognitive decline (SCD); dementia risk; cognitive complaints; functional decline; emotional well-being; early diagnosis and intervention

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Epigenetics and Epigenomics: Diagnosis and Prognosis

edited by Biaoru Li

submission deadline 31 Aug 2025 | 1 articles | Viewed by 829 | Submission Open

Keywords: epigenetics; epigenomics; diagnosis; prognosis

(This special issue belongs to the Section Clinical Laboratory Medicine)

Recent Advances in Diagnosis and Management of Heart Failure

edited by

Attila Frigy

submission deadline 31 Aug 2025 | 1 articles | Viewed by 814 | Submission Open

Keywords: heart failure diagnosis; therapeutic advances; multidisciplinary care; personalized medicine; advanced imaging; novel biomarkers; emerging therapies

(This special issue belongs to the Section Medical Imaging and Theranostics)

Thyroid Cancer: Types, Symptoms, Diagnosis and Management

edited by

Mara Carsote

, Mihai-Lucian Ciobica and

Claudiu Nistor

submission deadline 31 Aug 2025 | 2 articles | Viewed by 745 | Submission Open

Keywords: thyroid neoplasia; thyroiditis; imaging; functional imaging; thyroidectomy; tumor markers; histological exam; molecular findings; pediatric population; pregnancy and thyroid conditions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Challenges in Sports Cardiology—2nd Edition

edited by

Łukasz A. Małek

submission deadline 31 Aug 2025 | 1 articles | Viewed by 739 | Submission Open

Keywords: sports cardiology; MRI; echocardiography; heart rate

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Diagnosis and Management of Endometrial Cancer

edited by

Fulvio Borella

submission deadline 31 Aug 2025 | Viewed by 601 | Submission Open

Keywords: cancer biology; gynecologic oncology; tumor biomarkers; cancer diagnostics; breast cancer; ovarian cancer; endometrial cancer; vulvar cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Radiology in Head and Neck Diseases

edited by

Daniel Ginat

submission deadline 31 Aug 2025 | 1 articles | Viewed by 558 | Submission Open

Keywords: head ; neck ; imaging ; radiology ; magnetic resonance imaging ; computed tomography

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advances in Nuclear Medicine and Molecular Imaging

edited by

Gabriele Masselli

submission deadline 31 Aug 2025 | 1 articles | Viewed by 474 | Submission Open

Keywords: cancer; cardiovascular imaging; neurodegenerative conditions; computed tomography; molecular imaging; neuroimaging; positron emission tomography (PET); single-photon emission computed tomography (SPECT); nuclear medicine; molecular imaging; theranostics; response evaluation

(This special issue belongs to the Section Medical Imaging and Theranostics)

Progression of Ano-Genital Intraepithelial Neoplasia and Tumors in Relation to Biomarkers

edited by Attila Louis Major

submission deadline 31 Aug 2025 | Viewed by 437 | Submission Open

Keywords: intraepithelial neoplasia: cervical; vaginal; vulvar; anal; high-risk human papillomavirus (hr HPV); cancer biomarkers; oncoproteins; P16; Ki-67; immunoscore; epigenetic tests; methylation; prediction of cancer progression; HPV oncogenes E6 and E7; condyloma acuminata; condylomata acuminata gigantea (Buschke– Lö wenstein tumor); molecular; immunologic; and genetic risk factors for persistent and recurrent high-risk HPV infection; anamnestic risk factors for persistent and recurrent high-risk HPV infection; non-HPV-related precancer and cancer of ano-genital organs

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Risk and Prediction of Sudden Cardiac Death and Arrhythmias

edited by

Marisa Varrenti

submission deadline 31 Aug 2025 | Viewed by 351 | Submission Open

Keywords: arrhythmic risk stratification; sudden death; genetics; cardiomyopathy; cardiac magnetic resonance; ventricular arrhythmias; heart failure

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Integrating Health Informatics and Artificial Intelligence for Advanced Medicine

edited by

Joaquim Carreras

submission deadline 31 Aug 2025 | Viewed by 304 | Submission Open

Keywords: artificial intelligence; machine learning; artificial neural networks; prognosis; treatment; medicine; health care; pathology

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Recent Progress in Abdominal Ultrasound

edited by Andrea Boccatonda,

Antonio Corvino

and

Giulio Cocco

submission deadline 31 Aug 2025 | Viewed by 257 | Submission Open

Keywords: ultrasound; abdomen; CEUS; doppler; bowel

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnosis of Aortic Stenosis—2nd Edition

edited by

Maria Angela Losi

submission deadline 31 Aug 2025 | Viewed by 238 | Submission Open

Keywords: aortic stenosis; diagnosis; prognosis; cardiovascular imaging; echocardiography

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Diagnosis and Management of Retinopathy—2nd Edition

edited by

Joanna Gołȩbiewska

submission deadline 31 Aug 2025 | Viewed by 229 | Submission Open

Keywords: diabetic retinopathy; hypertensive retinopathy; inherited retinal diseases; imaging; OCT

(This special issue belongs to the Section Medical Imaging and Theranostics)

Pathophysiologic Mechanisms, Diagnosis and Management of Venous Thromboembolism

edited by Emanuele Valeriani

submission deadline 31 Aug 2025 | Viewed by 186 | Submission Open

Keywords: anticoagulants; deep vein thrombosis; diagnosis; pathophysiology; pulmonary embolism; venous thrombosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnosis and Management of Fungal Infections: Recent Advances and Coming Challenges

edited by Emily Avitan-Hersh

submission deadline 31 Aug 2025 | Viewed by 181 | Submission Open

Keywords: fungal infection diagnosis; management strategies; antifungal therapy; collaborative care; diagnostic techniques

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Traumatology: The Essential Role of Imaging in Diagnosis and Management

edited by

Meng-Yu Wu

and

Jui-Yuan Chung

submission deadline 31 Aug 2025 | Viewed by 179 | Submission Open

Keywords: traumatology; injury; mortality; functional outcomes; prehospital care; triage

(This special issue belongs to the Section Medical Imaging and Theranostics)

Innovative Advances in Diagnosis Through Artificial Intelligence

edited by Jorge Mateo Sotos

submission deadline 31 Aug 2025 | Viewed by 177 | Submission Open

Keywords: artificial intelligence; medical diagnostics; predictive analytics; machine learning; deep learning; digital pathology; early disease detection; personalized medicine; smart healthcare

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Artificial Intelligence and Big Data in Digestive Healthcare

edited by Hélder Cardoso and

Miguel Mascarenhas

submission deadline 31 Aug 2025 | Viewed by 176 | Submission Open

Keywords: artificial intelligence; big data; digestive system diseases; digestive system neoplasms; electronic health records; endoscopy; precision medicine

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Prenatal Diagnosis: From Morphological Evaluation to Genetic Testing

edited by

Antonio Pizzuti

and

Gioia Mastromoro

submission deadline 31 Aug 2025 | Viewed by 173 | Submission Open

Keywords: prenatal diagnosis; fetal ultrasound (US); fetal magnetic resonance imaging (MRI); chromosomal microarray analysis; next-generation sequencing; exome sequencing; genome sequencing; non-invasive prenatal screening; non-invasive prenatal diagnosis

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Application of Cone Beam Computed Tomography for Maxillofacial Diseases, Third Edition

edited by

Yiu Yan Leung

submission deadline 31 Aug 2025 | Viewed by 157 | Submission Open

Keywords: cone-beam computed tomography; imaging; radiology; oral and maxillofacial surgery; dentistry; diagnosis; risk management; 3D printing; artificial intelligence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Game-Changing Concepts in Reproductive Health

edited by Mark I. Evans and Christian R. Macedonia

submission deadline 31 Aug 2025 | Viewed by 107 | Submission Open

Keywords: pregnancy; artificial intelligence; prenatal diagnosis; genetic sequencing; diagnostic tests; screening tests; public policy; electronic fetal monitoring; introducing new technologies

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Current Trends and Future Directions in Radiotheragnostic Research: A Special Issue in Collaboration with ISRT 2025

edited by

Kalevi Kairemo

submission deadline 31 Aug 2025 | Viewed by 106 | Submission Open

Keywords: precision oncology; oncology; positron emission tomography; radionuclide therapy; targeted therapy; targeted alpha therapy; PSMA; prostate cancer; neuroendocrine neoplasms; somatostatin analogs; daughter radionuclides; dosimetry; small-scale/micro-dosimetry; radiobiology; target chemistry

(This special issue belongs to the Section Medical Imaging and Theranostics)

Eye Diseases: Diagnosis and Management—2nd Edition

edited by

Ramin Khoramnia

submission deadline 30 Sep 2025 | 20 articles | Viewed by 37197 | Submission Open

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Deep Learning in Medical and Biomedical Image Processing

edited by

Shuyue Guan

submission deadline 30 Sep 2025 | 8 articles | Viewed by 24655 | Submission Open

Keywords: deep learning; medical and biomedical image processing; model explainability and evaluation; generative model; machine learning

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Machine-Learning-Based Disease Diagnosis and Prediction

edited by Fakhar Abbas

submission deadline 30 Sep 2025 | 16 articles | Viewed by 24454 | Submission Open

Keywords: development and validation of machine learning models for disease diagnosis and prediction; integration of multimodal data (e.g.; imaging; genomic; and clinical) for enhanced diagnostic accuracy; artificial intelligence in healthcare; ethical and regulatory considerations in the deployment of machine learning for healthcare applications; case studies and applications of machine learning in specific disease domains (e.g.; cancer; cardiovascular diseases; and neurodegenerative disorders); comparative studies and benchmarking of machine learning approaches for disease diagnosis and prediction; healthcare analytics; bioinformatics; medical imaging analysis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

New Diagnostic and Testing Strategies for Infectious Diseases

edited by

Fernanda De-Paris

submission deadline 30 Sep 2025 | 8 articles | Viewed by 18539 | Submission Open

Keywords: infectious diseases diagnosis; clinical laboratory techniques; molecular biology; infection control; virulence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Imaging Diagnosis in Abdomen, 2nd Edition

edited by

Piero Boraschi

and

Francescamaria Donati

submission deadline 30 Sep 2025 | 8 articles | Viewed by 18463 | Submission Open

Keywords: ultrasound computed tomography; MR imaging; PET imaging diagnosis; oncologic imaging; therapeutic response assessment; biomarkers; multidisciplinary management

(This special issue belongs to the Section Medical Imaging and Theranostics)

Respiratory Diseases: Diagnosis and Management

edited by Ori Wand and

Shimon Izhakian

submission deadline 30 Sep 2025 | 12 articles | Viewed by 17994 | Submission Open

Keywords: interstitial lung diseases; chronic obstructive pulmonary disease; asthma; COVID-19; lung cancer; interventional pulmonology

(This special issue belongs to the Section Clinical Diagnosis and Prognosis)

Advances in Endoscopy

edited by

Emanuele Sinagra

and

Francesco Vito Mandarino

submission deadline 30 Sep 2025 | 6 articles | Viewed by 12123 | Submission Open

(This special issue belongs to the Section Medical Imaging and Theranostics)

Periodontal Disease: Diagnosis and Management

edited by

Francesco D’Ambrosio

submission deadline 30 Sep 2025 | 7 articles | Viewed by 12073 | Submission Open

Keywords: periodontal disease; periodontitis; management; diagnosis; biomarker; periodontology

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Advances in Laboratory Markers of Human Disease

edited by

Mina Hur

submission deadline 30 Sep 2025 | 8 articles | Viewed by 10688 | Submission Open

Keywords: laboratory biomarkers; genomic; proteomics; molecular diagnostics; clinical chemistry

(This special issue belongs to the Section Clinical Laboratory Medicine)

Challenges in Urology: From the Diagnosis to the Management

edited by

and

submission deadline 30 Sep 2025 | 6 articles | Viewed by 9883 | Submission Open

Keywords: challenges; complications; rare; surgery; cancer

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

The Future of Diagnostics: Exploring the Role of Artificial Intelligence in Medicine

edited by

Shang-Ming Zhou

, Neil Vaughan and Jiaxiang Zhang

submission deadline 30 Sep 2025 | 3 articles | Viewed by 8214 | Submission Open

Keywords: diagnostics; artificial intelligence; medicine; healthcare; future

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Imaging for the Diagnosis of Obstetric and Gynecological Diseases

edited by

Nicolae Gica

submission deadline 30 Sep 2025 | 5 articles | Viewed by 8093 | Submission Open

Keywords: diagnosis; imaging; gynecology and obstetrics; gynecological cancer; hysteroscopy; ovarian disease

(This special issue belongs to the Section Medical Imaging and Theranostics)

Diagnostic Imaging in Gastrointestinal and Liver Diseases

edited by

Ruxandra Mare

and

Ioan Sporea

submission deadline 30 Sep 2025 | 5 articles | Viewed by 6948 | Submission Open

Keywords: ultrasonography; elastography; multiparametric ultrasound; contrast-enhanced ultrasound; endoscopic ultrasound; contrast-enhanced endoscopic ultrasound; computer tomography; magnetic resonance imaging; gastrointestinal diseases; diffuse liver disease; focal liver lesions

(This special issue belongs to the Section Medical Imaging and Theranostics)

Advanced Musculoskeletal Imaging in Clinical Diagnostics

edited by

Hans-Jonas Meyer

submission deadline 30 Sep 2025 | 5 articles | Viewed by 5722 | Submission Open

Keywords: musculoskeletal imaging; cancer imaging; textural analysis; radiomics; MRI; CT; PET

(This special issue belongs to the Section Medical Imaging and Theranostics)

New Trends in the Diagnosis of Gynecological and Obstetric Diseases

edited by

Razvan Socolov

and Laurentiu Pirtea

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5672 | Submission Open

Keywords: obstetrics and gynecology diagnostics; screening; artificial intelligence; test accuracy

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Recent Advances in Breast Cancer Imaging

edited by

Tim Duong

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5488 | Submission Open

Keywords: breast cancer; neoadjuvant chemotherapy; axillary lymph nodes; molecular subtypes; hormonal receptor positive; medical oncology; breast surgery; breast cancer metastasis; pathological complete response; breast cancer recurrence

(This special issue belongs to the Section Medical Imaging and Theranostics)

Recent Advancements in the Diagnostics of Prostatitis

edited by

Alberto Trinchieri

and

Florian Wagenlehner

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5391 | Submission Open

Keywords: prostatitis; diagnostics; biomarkers; microbiology; imaging technologies; MRI; ultrasound; precision medicine; inflammatory proteins; genetic markers; artificial intelligence

(This special issue belongs to the Section Diagnostic Microbiology and Infectious Disease)

Artificial Intelligence in the Diagnostics of Dental Diseases, 2nd Edition

edited by Hakan Turkkahraman

submission deadline 30 Sep 2025 | 4 articles | Viewed by 5365 | Submission Open

Keywords: artificial intelligence; machine learning; neural networks; dental diseases; clinical decision support systems; medical diagnosis

(This special issue belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)

Diagnosis and Management of Metabolic Bone Diseases: 2nd Edition

edited by

Patryk Lipiński

and

Anna Tylki-Szymańska

submission deadline 30 Sep 2025 | 5 articles | Viewed by 4787 | Submission Open

Keywords: inborn errors of metabolism; inherited metabolic diseases; bone metabolism/health; short stature; skeletal; disturbances in calcium and phosphorus metabolism; hypophosphatemic rickets; hypophosphatasia

(This special issue belongs to the Section Pathology and Molecular Diagnostics)

Diagnostic Imaging in Neurological Diseases

edited by

Daniele Coraci

submission deadline 30 Sep 2025 | 8 articles | Viewed by 4701 | Submission Open

Keywords: diagnostic imaging; neurological diseases/disorders; central nervous system; imaging techniques; magnetic resonance imaging (MRI); positron emission tomography (PET); diagnostic modalities

(This special issue belongs to the Section Medical Imaging and Theranostics)

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