Molecular and Immunological Research on Colorectal Cancer: Pathogenesis, Microenvironment, and Future Therapies
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Biochemistry, Molecular and Cellular Biology".
Deadline for manuscript submissions: 30 April 2026
Special Issue Editor
Interests: colorectal cancer pathogenesis; helminth infections and cancer; immunology and inflammation; biotherapeutic development
Special Issue Information
Dear Colleagues,
Colorectal cancer (CRC) is a significant global health concern, driven by intricate interactions among genetic, epigenetic, immunological, and environmental factors. This Special Issue seeks to showcase recent advances in understanding the molecular mechanisms of CRC pathogenesis and progression, including the aggressive behavior of cancer cells. We also aim to highlight research on tumor microenvironment dynamics, inflammation-related signaling pathways, and the influence of microorganisms on chemotherapy response. We welcome original research and review articles that investigate novel biomarkers, therapeutic targets, and biotherapeutic strategies, as well as studies exploring immune modulation and the role of microbiota in CRC development. By embracing multidisciplinary perspectives, this issue aspires to deepen our understanding of CRC biology and inspire innovative approaches to its diagnosis, treatment, and prevention.
Dr. Mónica G Mendoza-Rodríguez
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- colorectal cancer (CRC)
- tumor microenvironment
- chemotherapy resistance
- inflammation-related signalling
- biotherapeutics
- immune response
- cancer progression
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
