Molecular Mechanisms, Diet and Therapeutic Interventions in Neurological Disorders
A Special Issue of Current Issues in Molecular Biology (ISSN 1467-3045) belonging to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 2681
Editors
Interests: aging; nutrition; inflammation nutraceuticals; longevity; centenarians
Special Issues, Collections and Topics in MDPI journals
Interests: alzheimer; neurodegeneration; nutrition; neurobiology; neuroprotection
Special Issue Information
Dear Colleagues,
Neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative conditions, are characterized by complex molecular changes involving inflammation, mitochondrial dysfunction, impaired proteostasis, and metabolic imbalance. Emerging evidence suggests that diet and targeted nutritional interventions can influence several of these pathogenic pathways, affecting neuronal resilience and systemic bioenergetics. Specifically, dietary patterns such as the Mediterranean diet and fasting-mimicking regimens show promise in modulating oxidative stress, insulin signalling, autophagy, and neuroinflammatory processes. Advances in high-sensitivity plasma biomarkers now allow for more accurate assessment of the molecular effects of nutritional and lifestyle interventions during early disease stages. This Special Issue will compile frontier research exploring the molecular mechanisms linking diet, metabolism, and neurodegeneration, with a focus on translational biomarkers and therapeutic options. We invite original research articles, reviews, and methodological studies that examine how dietary strategies and metabolic interventions can aid prevention, early detection, and disease modification in neurological disorders.
Dr. Giulia Accardi
Dr. Francesco Cacciabaudo
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- neurodegeneration
- metabolic interventions
- intermittent fasting
- Mediterranean diet
- molecular biomarkers
- neuroinflammation
- mitochondrial dysfunction
- precision nutrition
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