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Molecular Insights and Unique Characteristics in Adolescent and Young Adult Oncology

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 October 2025

Special Issue Editor


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Guest Editor
Pediatric Oncology Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy
Interests: clinical pharmacology; antineoplastic drugs; clinical trial; pediatric drugs
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue addresses the critical gap in oncology research for patients aged 15–39 years, a population that often falls between established pediatric and adult treatment paradigms. Recent molecular and genomic studies have revealed distinct biological characteristics of malignancies in this age group at the molecular level, warranting dedicated research attention.

The AYA (Adolescent and Young Adult) oncology population presents with unique tumor biology, molecular signatures, treatment responses, and survival outcomes that differ from both pediatric and older adult patients. Despite comprising approximately 5% of all cancer diagnoses, survival improvements in this age group have lagged behind those observed in pediatric and older adult populations. This Special Issue aims to highlight recent molecular advances in understanding these age-specific differences and translate them into improved clinical outcomes.

Dr. Antonio Ruggiero
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • adolescent
  • young adult
  • biology
  • treatment
  • outcome

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Published Papers

This special issue is now open for submission.
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