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Molecular Neuropsychiatry: Target Discovery for Mental Disorders

A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".

Deadline for manuscript submissions: 31 July 2026 | Viewed by 148

Special Issue Editors


E-Mail Website
Guest Editor
1. Department of Medicine and Health Technology Faculty of Health Sciences, Aalborg University, DK-9260 Gistrup, Denmark
2. National Centre for Register-based Research, Department of Public Health, Aarhus University, DK-8000 Aarhus C, Denmark
Interests: artificial intelligence; epidemiology; genetics; statistics

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Guest Editor Assistant
Department of Clinical Medicine, Aarhus University, DK-8000 Aarhus C, Denmark
Interests: genetic predisposition; environmental exposure; neuropsychiatric disorders

Special Issue Information

Dear Colleagues,

We are excited to announce a call for submissions for a Special Issue titled “Molecular Neuropsychiatry: Target Discovery for Mental Disorders.” Neuropsychiatric disorders—including major psychiatric illnesses, neurodevelopmental conditions, and neurodegenerative diseases—represent a substantial and growing global health burden. Elucidating the molecular and cellular mechanisms underlying these complex disorders is essential for the development of innovative diagnostic approaches and effective, targeted therapeutic strategies.

Recent advances have highlighted the critical roles of brain–immune interactions, intricate molecular and signaling networks, synaptic plasticity, and large-scale transcriptomic studies that have identified dysregulated genes and pathways associated with neuropsychiatric conditions. Despite this progress, significant challenges remain in translating molecular discoveries into clinically actionable targets and precision treatments. This Special Issue aims to provide a comprehensive platform for cutting-edge research and critical reviews that advance our understanding of molecular mechanisms in neuropsychiatric disorders.

In this Special Issue, topics of interest include, but are not limited to, the following:

  • Genetic and epigenetic regulation in neuropsychiatric disorders;
  • Non-coding RNAs and their role in brain function and disease progression;
  • Neuroinflammatory and neuroendocrine mechanisms;
  • Synaptic plasticity and dysregulated neural signaling pathways;
  • Biomarker discovery for diagnosis, prognosis, and therapeutic response;
  • Neuroimaging and molecular correlates of psychiatric disorders;
  • Pharmacogenomics and molecular targets for precision therapeutics;
  • Environmental and lifestyle influences on molecular pathways in mental health;
  • Molecular mechanisms underlying comorbidity across neuropsychiatric disorders. 

Dr. Fenfen Ge
Guest Editor

Dr. Yue Wang
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular targets
  • neuropsychiatric disorders
  • genetic and epigenetic regulation
  • transcriptomics
  • pharmacogenomics
  • brain–immune interactions
  • neural circuits and synaptic plasticity
  • biomarker discovery
  • omics approaches
  • precision psychiatry

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Published Papers

This special issue is now open for submission.
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