Scoliosis and Spinal Disorders: Molecular Biomarkers and Therapeutic Strategies
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Medicine".
Deadline for manuscript submissions: 31 October 2026 | Viewed by 695
Editor
Interests: molecular signaling in orthopaedic diseases; pathophysiology of osteoarthritis; biomarkers and pathological background of non-union fractures; bone metabolism basis of fragility fractures and management; pathophysiology and molecular basis of spinal deformities and spinal cord Injuries
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent research has unveiled significant findings regarding intracellular signaling events during Scoliotic and Spinal deformities’ development and progression in several pathologies. Current studies focus on the microscopic and macroscopic examination of the contribution of several molecules, such as cytokines, chemokines, growth factors, protein receptors and hormones, in intracellular signal transduction cascades. They aim to reveal potential therapeutic targets for the prevention and management of Scoliotic and Spinal disorders, along with biomarker indices to characterize the disease severity and effectiveness of the applied treatment. Nevertheless, the complexity of the molecular processes involved in Scoliotic and Spinal deformities’ pathogenesis and progression means that they remain little understood.
This Special Issue of CIMB aims to provide preclinical and clinical evidence on the pathophysiology of Spinal diseases and demonstrate potential therapeutic or diagnostic applications based on recent experimental advancements. Original research and review articles will be considered if they clearly add value to the available body of literature. These articles’ thematic scope should comprise the clinical, diagnostic, prognostic and therapeutic aspects of these disorders and their molecular background.
The topics of interest include, but are not limited to, the following:
- In vitro experimental discoveries regarding the molecular signaling in Scoliosis and other Spinal deformities;
- The results from in vivo and animal model experiments investigating the functional role of intracellular molecules;
- Examinations of the expression of cytokines or growth factors that may be used as biomarkers for prognostic or diagnostic purposes;
- Studies that investigate the relationship between Spinal deformities’ clinical characteristics and specific biochemical pathways;
- Potential target therapies for the management of Scoliosis and Spinal malformations;
- The metabolic basis of Scoliosis progression.
We look forward to receiving your contributions.
Dr. Angelos Kaspiris
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Current Issues in Molecular Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- intracellular interactions during the progression of spinal disorders
- molecular signaling in scoliosis
- growth factor expression in spinal disorders and deformities
- biomarkers
- molecular-driven treatment
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
