Advances in Pharmacotherapeutic Strategies to Prevent Tumor Development, Progression and Treatment Resistance, 3rd Edition
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 30 September 2026 | Viewed by 1783
Editor
Interests: tumor microenvironment; cell–cell signaling; cell metabolism; hypoxia; oxidative stress; drug repurposing; ovarian cancer; breast cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Recent advances in our understanding of the molecular mechanisms underlying cancer progression have promoted the de novo development of novel small molecules and facilitated drug repositioning, complementing contemporary therapeutic approaches for enhancing patient survival. Pharmacotherapeutics that target nonredundant pathways in tumor cells required for proliferation, survival, and unchecked self-renewal capacity have provided additional strategies for improving the standard of care in treating many forms of cancer. Moreover, appreciating the importance of targeting the stromal compartment (e.g., immune cells, fibroblasts, and adipocytes) has further exposed therapeutic liabilities in the tumor microenvironment, which may present additional options for preventing tumor cell growth and suppressing cancer cell resistance to therapeutics. Further identification and elaboration of necessary intracellular pathways and cell–cell signaling mechanisms may improve new pharmacotherapeutic approaches for preventing tumor development, progression, and treatment resistance.
This Special Issue of Current Issues in Molecular Biology is open for the submission of both original research articles and review articles focused on the advances in our understanding of actionable pharmacologic mechanisms for preventing cancer development and progression. Identifying and elaborating on these mechanisms may provide a path forward in improving patient care and outcomes.
To read the first and second volumes of our Special Issue, please click the following links:
https://www.mdpi.com/journal/cimb/special_issues/TH355V0O5G
https://www.mdpi.com/journal/cimb/special_issues/4637044RT6
Dr. Peter C. Hart
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cancer
- therapeutic resistance
- drug tolerance
- mechanisms of tumor development
- mechanisms of tumor progression
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