Bioinformatics in Human Disease Network Analysis
A special issue of Current Issues in Molecular Biology (ISSN 1467-3045). This special issue belongs to the section "Bioinformatics and Systems Biology".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 3
Special Issue Editor
Special Issue Information
Dear Colleagues,
Disease diagnosis and treatment are at the center of human health research. A lot of effort has gone into study of individual diseases, which has had great success in many cases, tracing back down to certain genes or even certain SNPs as the culprit at the molecular biology level. Yet, genes are not isolated entities in the cell; rather, genes—via their product proteins—interact with one another to fulfill cellular functions in many biochemical processes, and these interactions form a network with genes and proteins as nodes and interactions as edges; malfunction in one node has the potential to affect other nodes, manifesting as multiple symptoms. At the clinical level, comorbidity, which is the co-occurrence of two or more diseases, is observed and presents special challenges to disease diagnosis and treatment.
This Special Issue focuses on bioinformatics solutions to disease in the context of network analysis at both the genotype and phenotype levels, and anything in between, to shed light on the diagnosis and treatment of comorbid diseases. While original research is the main focus of this issue, technical notes on tools and software and review articles surveying state-of-the-art solutions, techniques, and resources, such as databases, are also welcome.
Dr. Li Liao
Guest Editor
Manuscript Submission Information
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Keywords
- human interactome
- comorbidity
- disease network
- disease interaction
- genotype
- gene–gene interaction
- graph analysis
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